63 Publications (Page 1 of 3)
A new Down syndrome rat model races forward
Trends in Genetics. | Journal Article
Increased dosage and treatment time of Epigallocatechin-3-gallate (EGCG) negatively affects skeletal parameters in normal mice and Down syndrome mouse models
Raza, JamalLaCombe, JonathanPatel, RoshniBlackwell, MatthewThomas, Jared RSloan, KourtneyWallace, Joseph M and Roper, Randall J
PLOS ONE. | Journal Article
Current Analysis of Skeletal Phenotypes in Down Syndrome
Current Osteoporosis Reports. | Journal Article
Influence of allelic differences in Down syndrome
Roper, Randall JRoper, Randall JHawley, LauraHawley, LauraGoodlett, Charles R and Goodlett, Charles R
Progress in brain research, vol. 251, pp. 29, 2020-00-00. | Journal Article
Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome
Thomas, Jared RLaCombe, JonathanLong, RachelLana-Elola, EvaWatson-Scales, SheonaWallace, Joseph MFisher, Elizabeth M.CTybulewicz, Victor L.J and Roper, Randall J
Bone. | Journal Article
Skeletal dynamics of Down syndrome: A developing perspective
LaCombe, Jonathan M. and Roper, Randall J.
Bone, vol. 133, pp. 115215. | Journal Article
Clinical identification of feeding and swallowing disorders in 0–6 month old infants with Down syndrome
Stanley, Maria AStanley, Maria AStanley, Maria AShepherd, NicoleShepherd, NicoleShepherd, NicoleDuvall, NicholeDuvall, NicholeDuvall, NicholeJenkinson, Sandra BJenkinson, Sandra BJenkinson, Sandra BJalou, Hasnaa EJalou, Hasnaa EJalou, Hasnaa EGivan, Deborah CGivan, Deborah CGivan, Deborah CSteele, Gregory HSteele, Gregory HSteele, Gregory HDavis, CharleneDavis, CharleneDavis, CharleneBull, Marilyn JBull, Marilyn JBull, Marilyn JWatkins, Donna UWatkins, Donna UWatkins, Donna URoper, Randall JRoper, Randall J and Roper, Randall J
American Journal of Medical Genetics Part A, vol. 179, (no. 2), pp. 182, February 2019. | Journal Article
Down syndrome mouse models have an abnormal enteric nervous system
Schill, Ellen M.Wright, Christina M.Jamil, AlishaLaCombe, Jonathan M.Roper, Randall J. and Heuckeroth, Robert O.
JCI Insight. | Journal Article
Usage of and attitudes about green tea extract and Epigallocathechin-3-gallate (EGCG) as a therapy in individuals with Down syndrome
Long, RachelLong, RachelDrawbaugh, Montana LDrawbaugh, Montana LDavis, Charlene MDavis, Charlene MGoodlett, Charles RGoodlett, Charles RWilliams, Jane RWilliams, Jane RRoper, Randall J and Roper, Randall J
Complementary Therapies in Medicine, vol. 45, pp. 241, August 2019. | Journal Article
Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes
Stringer, MeganStringer, M.Stringer, MeganAbeysekera, IrushiAbeysekera, I.Abeysekera, IrushiThomas, J.Thomas, JaredThomas, JaredLaCombe, J.LaCombe, JonathanLaCombe, JonathanStancombe, KaileyStancombe, KaileyStancombe, K.Stewart, RobertStewart, RobertStewart, R.J.Dria, K.J.Dria, KarlDria, KarlWallace, JosephWallace, J.M.Wallace, JosephGoodlett, CharlesGoodlett, CharlesGoodlett, C.R.Roper, RandallRoper, R.J. and Roper, Randall
Physiology and Behavior, vol. 177, pp. 230-241. | Journal Article
Targeting trisomic treatments: optimizing Dyrk1a inhibition to improve Down syndrome deficits
Stringer, MeganStringer, MeganGoodlett, Charles RGoodlett, Charles R.Roper, Randall J and Roper, Randall J.
Molecular Genetics & Genomic Medicine, vol. 5, pp. 451–465. | Journal Article
Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model
Abeysekera, IrushiAbeysekera, I.Thomas, J.Thomas, JaredGeorgiadis, Taxiarchis MGeorgiadis, T.M.Berman, A.G.Berman, Alycia GHammond, Max AHammond, M.A.Dria, Karl JDria, K.J.Wallace, Joseph MWallace, J.M.Roper, R.J. and Roper, Randall J
Molecular Nutrition and Food Research, vol. 60, pp. 717-726. | Journal Article
Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome
McElyea, S.D.McElyea, Samantha DStarbuck, John MStarbuck, J.M.Tumbleson-Brink, Danika MTumbleson-Brink, D.M.Harrington, EmilyHarrington, E.Blazek, J.D.Blazek, Joshua DGhoneima, A.Ghoneima, AhmedKula, KatherineKula, K.Roper, Randall J and Roper, R.J.
Human Molecular Genetics, vol. 25, pp. 4856-4869. | Journal Article
Abnormal mineralization of the Ts65Dn Down syndrome mouse appendicular skeleton begins during embryonic development in a Dyrk1a-independent manner.
Blazek, Joshua DMalik, Ahmed MTischbein, MaeveArbones, Maria LMoore, Clara S and Roper, Randall J
Mechanisms of development, vol. 136, pp. 133-142, May 2015. | Journal Article
Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model.
Stringer, MeganAbeysekera, IrushiDria, Karl JRoper, Randall J and Goodlett, Charles R
Pharmacology, biochemistry, and behavior, vol. 138, pp. 70-79, November 2015. | Journal Article
Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic.
Goffinski, AlidaGoffinski, AlidaStanley, Maria AStanley, Maria AShepherd, NicoleShepherd, NicoleDuvall, NicholeDuvall, NicholeJenkinson, Sandra BJenkinson, Sandra BDavis, CharleneDavis, CharleneBull, Marilyn JBull, Marilyn JRoper, Randall J and Roper, Randall J
American journal of medical genetics. Part A, vol. 167A, (no. 2), pp. 324-330, February 2015. | Journal Article
Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a.
Blazek, Joshua DAbeysekera, IrushiLi, Jiliang and Roper, Randall J
Human molecular genetics, vol. 24, (no. 20), pp. 5687-5696, October 15, 2015. | Journal Article
Commonality in Down and fetal alcohol syndromes.
Solzak, Jeffrey PLiang, YunZhou, Feng C and Roper, Randall
Birth defects research. Part A, Clinical and molecular teratology, vol. 97, (no. 4), pp. 187-97, 2013/Apr. | Journal Article
Non-trisomic homeobox gene expression during craniofacial development in the Ts65Dn mouse model of Down syndrome.
Billingsley, Cherie NAllen, Jared RBaumann, Douglas DDeitz, Samantha LBlazek, Joshua DNewbauer, AbbyDarrah, AndrewLong, Brad CYoung, BrandonClement, MarkDoerge, R W and Roper, Randall J
American journal of medical genetics. Part A, vol. 161A, (no. 8), pp. 1866-1874, August 2013. | Journal Article
Trying out genes for size: Experiential learning in the high school classroom
Blazek, J.D.Blazek, JoshuaCooper, GaryCooper, G.L.Judd, MariahJudd, M.V.Roper, R.J.Roper, RandallMarrs, Kathleen and Marrs, K.A.
American Biology Teacher, vol. 75, pp. 657-662. | Journal Article
Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice.
Blazek, Joshua DGaddy, AnnaMeyer, RachelRoper, Randall and Li, Jiliang
Bone, vol. 48, (no. 2), pp. 275-80, 2011/Feb. | Journal Article
Erratum: Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn (Mammalian Genome DOI: 10.1007/s00335-011- 9357-z)
Reinholdt, LauraReinholdt, L.G.Ding, YuemingDing, Y.Gilbert, Griffith JGilbert, G.J.Czechanski, AnneCzechanski, A.Solzak, J.P.Solzak, Jeffrey PRoper, R.J.Roper, Randall JJohnson, M.T.Johnson, Mark TDonahue, Leah RDonahue, L.R.Lutz, CathleenLutz, C.Davisson, Muriel T and Davisson, M.T.
Mammalian Genome, vol. 22. | Journal Article
Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn
Reinholdt, LauraDing, YuemingGilbert, Griffith TCzechanski, AnneSolzak, Jeffrey PRoper, RandallJohnson, Mark TDonahue, Leah RLutz, Cathleen and Davisson, Muriel T
Mammalian Genome, vol. 22, (no. 11-12), pp. 685-691, 2011. | Journal Article
Trisomic and Allelic Differences Influence Phenotypic Variability During Development of Down Syndrome Mice
Deitz, Samantha L and Roper, Randall
Genetics, vol. 189, (no. 4), pp. 1487-95, Dec 2011. | Journal Article
Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome.
Blazek, Joshua DBillingsley, Cherie NNewbauer, Abby and Roper, Randall
Developmental dynamics : an official publication of the American Association of Anatomists, vol. 239, (no. 6), pp. 1645-53, 2010/Jun. | Journal Article