94 Publications (Page 1 of 4)
2023
Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis. Development
. | Journal Article
2022
Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis. Journal of Cardiovascular Development and Disease
 
Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis.
2021
Deletion of a Hand1 lncRNA-Containing Septum Transversum Enhancer Alters lncRNA Expression but Is Not Required for Hand1 Expression
Journal of Cardiovascular Development and Disease. | Journal Article
 
HAND transcription factors cooperatively specify the aorta and pulmonary trunk
Developmental Biology. | Journal Article
 
Mechanisms Underlying Cardiomyocyte Development: Can We Exploit Them to Regenerate the Heart?
Current Cardiology Reports. | Journal Article
2020
HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure
Firulli, Beth A⋅Firulli, Beth A⋅Firulli, Beth A⋅George, Rajani M⋅George, Rajani M⋅George, Rajani M⋅Harkin, Jade⋅Harkin, Jade⋅Harkin, Jade⋅Toolan, Kevin P⋅Toolan, Kevin P⋅Toolan, Kevin P⋅Gao, Hongyu⋅Gao, Hongyu⋅Gao, Hongyu⋅Liu, Yunlong⋅Liu, Yunlong⋅Liu, Yunlong⋅Zhang, Wenjun⋅Zhang, Wenjun⋅Zhang, Wenjun⋅Field, Loren J⋅Field, Loren J⋅Field, Loren J⋅Liu, Ying⋅Liu, Ying⋅Liu, Ying⋅Shou, Weinian⋅Shou, Weinian⋅Shou, Weinian⋅Payne, Ronald Mark⋅Payne, Ronald Mark⋅Payne, Ronald Mark⋅Rubart-von der Lohe, Michael⋅Rubart-von der Lohe, Michael⋅Rubart-von der Lohe, Michael⋅Firulli, Anthony B⋅Firulli, Anthony B and Firulli, Anthony B
Cardiovascular Research, vol. 116, (no. 3), pp. 618, 20200301. | Journal Article
 
Mis-Expression of a Cranial Neural Crest Cell-Specific Gene Program in Cardiac Neural Crest Cells Modulates HAND Factor Expression, Causing Cardiac Outflow Tract Phenotypes
Vincentz, Joshua W⋅Clouthier, David E and Firulli, Anthony B
Journal of cardiovascular development and disease, vol. 7, (no. 2), pp. 13, 2020-Apr-20. | Journal Article
 
SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects
Durbin, Matthew D.⋅O’Kane, James⋅Lorentz, Samuel⋅Firulli, Anthony B. and Ware, Stephanie M.
Developmental Biology, vol. 464, pp. 124–136. | Journal Article
 
The heart of the neural crest: cardiac neural crest cells in development and regeneration
Development. | Journal Article
2019
Hand Factors in Cardiac Development
George, Rajani M and Firulli, Anthony B
The Anatomical Record, vol. 302, (no. 1), pp. 107, January 2019. | Journal Article
 
Partially Penetrant Cardiac Neural Crest Defects in Hand1 Phosphomutant Mice: Dimer Choice That Is Not So Critical
Firulli, Beth and Firulli, Anthony
Pediatric Cardiology, vol. 40, (no. 7), pp. 1344, 20191000. | Journal Article
 
Twist1 Inactivation in Dmp1-Expressing Cells Increases Bone Mass but Does Not Affect the Anabolic Response to Sclerostin Neutralization
Lewis, Karl J⋅Lewis, Karl J⋅Choi, Roy B-J⋅Choi, Roy B⋅Pemberton, Emily Z⋅Pemberton, Emily Z⋅Bullock, Whitney A⋅Bullock, Whitney A⋅Firulli, Anthony B⋅Firulli, Anthony B⋅Robling, Alexander G and Robling, Alexander G
International Journal of Molecular Sciences, vol. 20, (no. 18), 2019. | Journal Article
 
Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function
Vincentz, Joshua⋅Vincentz, Joshua⋅Firulli, Beth⋅Firulli, Beth⋅Toolan, Kevin⋅Toolan, Kevin⋅Arking, Dan⋅Arking, Dan⋅Sotoodehnia, Nona⋅Sotoodehnia, Nona⋅Wan, Juyi⋅Wan, Juyi⋅Chen, Peng-Sheng⋅Chen, Peng Sheng⋅Gier-de Vries, Corrie⋅Gier-de Vries, Corrie⋅Christoffels, Vincent⋅Christoffels, Vincent⋅Lohe, Michael⋅Lohe, Michael⋅Firulli, Anthony and Firulli, Anthony
Circulation research, vol. 125, (no. 6), pp. 589, 2019. | Journal Article
2018
Abstract 17134: Variation Within a Left Ventricle-Specific Hand1 Enhancer Impairs Gata Transcription Factor Binding and Disrupts Ventricular Conduction System Development
Vincentz, Joshua⋅Firulli, Beth⋅Toolan, Kevin⋅Arking, Dan⋅Sotoodehnia, Nona⋅Wan, Juyi⋅Chen, Peng-Sheng⋅de Gier-de Vries, Corrie⋅Christoffels, Vincent⋅Rubart-von der Lohe, Michael and Firulli, Anthony
Circulation, vol. 138, (no. Suppl_1 Suppl 1), pp. A17134, 2018-November-6. | Journal Article
 
Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification
Miao, Lianjie⋅Li, Jingjing⋅Li, Jun⋅Tian, Xueying⋅Lu, Yangyang⋅Hu, Saiyang⋅Shieh, David⋅Kanai, Ryan⋅Zhou, Bo-Yang⋅Zhou, Bin⋅Liu, Jiandong⋅Firulli, Anthony B⋅Martin, James F⋅Singer, Harold⋅Zhou, Bin⋅Xin, Hongbo and Wu, Mingfu
Scientific reports, vol. 8, (no. 1), pp. 14, 2018-02-08. | Journal Article
2017
Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis
Firulli, Beth A⋅Firulli, Beth A⋅Milliar, Hannah⋅Milliar, Hannah⋅Toolan, Kevin P⋅Toolan, Kevin P⋅Harkin, Jade⋅Harkin, Jade⋅Fuchs, Robyn K⋅Fuchs, Robyn K⋅Robling, Alex G⋅Robling, Alex G⋅Firulli, Anthony B and Firulli, Anthony B
Development (Cambridge, England), vol. 144, (no. 13), pp. 2489, 2017-07-01. | Journal Article
 
Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function
Vincentz, Joshua W⋅Toolan, Kevin P⋅Zhang, Wenjun and Firulli, Anthony B
PLoS genetics, vol. 13, (no. 7), pp. e1006922, 2017-Jul. | Journal Article
 
Nkx2.5 regulates endothelin converting enzyme‐1 during pharyngeal arch patterning
Iklé, Jennifer M⋅Iklé, Jennifer M⋅Tavares, Andre L⋅Tavares, Andre L. P⋅King, Marisol⋅King, Marisol⋅Ding, Hailei⋅Ding, Hailei⋅Colombo, Sophie⋅Colombo, Sophie⋅Firulli, Beth A⋅Firulli, Beth A⋅Firulli, Anthony B⋅Firulli, Anthony B⋅Targoff, Kimara L⋅Targoff, Kimara L⋅Yelon, Deborah⋅Yelon, Deborah⋅Clouthier, David E and Clouthier, David E
genesis, vol. 55, (no. 3), pp. n/a, March 2017. | Journal Article
 
The HAND1 frameshift A126FS mutation does not cause hypoplastic left heart syndrome in mice
Firulli, Beth A⋅Toolan, Kevin P⋅Harkin, Jade⋅Millar, Hannah⋅Pineda, Santiago and Firulli, Anthony B
Cardiovascular research, vol. 113, (no. 14), pp. 1742, 2017-Dec-01. | Journal Article
2016
Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap
Vincentz, Joshua⋅Casasnovas, Jose⋅Barnes, Ralston⋅Que, Jianwen⋅Clouthier, David⋅Wang, Jun and Firulli, Anthony
Proceedings of the National Academy of Sciences of the United States of America, vol. 113, (no. 27), pp. 7568, 20160705. | Journal Article
 
Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification
Li, Jingjing⋅Li, Jingjing⋅Miao, Lianjie⋅Miao, Lianjie⋅Shieh, David⋅Shieh, David⋅Spiotto, Ernest⋅Spiotto, Ernest⋅Li, Jian⋅Li, Jian⋅Zhou, Bin⋅Zhou, Bin⋅Paul, Antoni⋅Paul, Antoni⋅Schwartz, Robert J⋅Schwartz, Robert J⋅Firulli, Anthony B⋅Firulli, Anthony B⋅Singer, Harold A⋅Singer, Harold A⋅Huang, Guoying⋅Huang, Guoying⋅Wu, Mingfu and Wu, Mingfu
Cell Reports, vol. 15, (no. 1), pp. 170, 2016-04-05. | Journal Article
2014
Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis
Firulli, Beth A⋅Firulli, Beth A⋅Fuchs, Robyn K⋅Fuchs, Robyn K⋅Vincentz, Joshua W⋅Vincentz, Joshua W⋅Clouthier, David E⋅Clouthier, David E⋅Firulli, Anthony B and Firulli, Anthony B
Development (Cambridge, England), vol. 141, (no. 15), pp. 3061, 2014-Aug. | Journal Article
 
Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration
Schindler, Yocheved L⋅Schindler, Yocheved L⋅Garske, Kristina M⋅Garske, Kristina M⋅Wang, Jinhu⋅Wang, Jinhu⋅Firulli, Beth A⋅Firulli, Beth A⋅Firulli, Anthony B⋅Firulli, Anthony B⋅Poss, Kenneth D⋅Poss, Kenneth D⋅Yelon, Deborah and Yelon, Deborah
Development (Cambridge, England), vol. 141, (no. 16), pp. 3122, 2014-Aug. | Journal Article
 
Hand2 Is an Essential Regulator for Two Notch-Dependent Functions within the Embryonic Endocardium
VanDusen, Nathan J⋅VanDusen, Nathan J⋅Casanovas, Jose⋅Casanovas, Jose⋅Vincentz, Joshua W⋅Vincentz, Joshua W⋅Firulli, Beth A⋅Firulli, Beth A⋅Osterwalder, Marco⋅Osterwalder, Marco⋅Lopez-Rios, Javier⋅Lopez-Rios, Javier⋅Zeller, Rolf⋅Zeller, Rolf⋅Zhou, Bin⋅Zhou, Bin⋅Grego-Bessa, Joaquim⋅Grego-Bessa, Joaquim⋅De La Pompa, José Luis⋅De La Pompa, José Luis⋅Shou, Weinian⋅Shou, Weinian⋅Firulli, Anthony B and Firulli, Anthony B
Cell Reports. | Journal Article