95 Publications (Page 1 of 4)
Identification and characterization of Hand2 upstream genomic enhancers active in developing stomach and limbs. Developmental Dynamics
. | Journal Article
Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis. Development
. | Journal Article
Neonatal Deletion of Hand1 and Hand2 within Murine Cardiac Conduction System Reveals a Novel Role for HAND2 in Rhythm Homeostasis. Journal of Cardiovascular Development and Disease
Single cell evaluation of endocardial HAND2 gene regulatory networks reveals critical HAND2 dependent pathways impacting cardiac morphogenesis.
Deletion of a Hand1 lncRNA-Containing Septum Transversum Enhancer Alters lncRNA Expression but Is Not Required for Hand1 Expression
Journal of Cardiovascular Development and Disease. | Journal Article
HAND transcription factors cooperatively specify the aorta and pulmonary trunk
Developmental Biology. | Journal Article
Mechanisms Underlying Cardiomyocyte Development: Can We Exploit Them to Regenerate the Heart?
Current Cardiology Reports. | Journal Article
HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure
Firulli, Beth AFirulli, Beth AFirulli, Beth AGeorge, Rajani MGeorge, Rajani MGeorge, Rajani MHarkin, JadeHarkin, JadeHarkin, JadeToolan, Kevin PToolan, Kevin PToolan, Kevin PGao, HongyuGao, HongyuGao, HongyuLiu, YunlongLiu, YunlongLiu, YunlongZhang, WenjunZhang, WenjunZhang, WenjunField, Loren JField, Loren JField, Loren JLiu, YingLiu, YingLiu, YingShou, WeinianShou, WeinianShou, WeinianPayne, Ronald MarkPayne, Ronald MarkPayne, Ronald MarkRubart-von der Lohe, MichaelRubart-von der Lohe, MichaelRubart-von der Lohe, MichaelFirulli, Anthony BFirulli, Anthony B and Firulli, Anthony B
Cardiovascular Research, vol. 116, (no. 3), pp. 618, 20200301. | Journal Article
Mis-Expression of a Cranial Neural Crest Cell-Specific Gene Program in Cardiac Neural Crest Cells Modulates HAND Factor Expression, Causing Cardiac Outflow Tract Phenotypes
Vincentz, Joshua WClouthier, David E and Firulli, Anthony B
Journal of cardiovascular development and disease, vol. 7, (no. 2), pp. 13, 2020-Apr-20. | Journal Article
SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects
Durbin, Matthew D.O’Kane, JamesLorentz, SamuelFirulli, Anthony B. and Ware, Stephanie M.
Developmental Biology, vol. 464, pp. 124–136. | Journal Article
The heart of the neural crest: cardiac neural crest cells in development and regeneration
Development. | Journal Article
Hand Factors in Cardiac Development
George, Rajani M and Firulli, Anthony B
The Anatomical Record, vol. 302, (no. 1), pp. 107, January 2019. | Journal Article
Partially Penetrant Cardiac Neural Crest Defects in Hand1 Phosphomutant Mice: Dimer Choice That Is Not So Critical
Firulli, Beth and Firulli, Anthony
Pediatric Cardiology, vol. 40, (no. 7), pp. 1344, 20191000. | Journal Article
Twist1 Inactivation in Dmp1-Expressing Cells Increases Bone Mass but Does Not Affect the Anabolic Response to Sclerostin Neutralization
Lewis, Karl JLewis, Karl JChoi, Roy BChoi, Roy B-JPemberton, Emily ZPemberton, Emily ZBullock, Whitney ABullock, Whitney AFirulli, Anthony BFirulli, Anthony BRobling, Alexander G and Robling, Alexander G
International Journal of Molecular Sciences, vol. 20, (no. 18), 2019. | Journal Article
Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function
Vincentz, JoshuaVincentz, JoshuaFirulli, BethFirulli, BethToolan, KevinToolan, KevinArking, DanArking, DanSotoodehnia, NonaSotoodehnia, NonaWan, JuyiWan, JuyiChen, Peng ShengChen, Peng-ShengGier-de Vries, CorrieGier-de Vries, CorrieChristoffels, VincentChristoffels, VincentLohe, MichaelLohe, MichaelFirulli, Anthony and Firulli, Anthony
Circulation research, vol. 125, (no. 6), pp. 589, 2019. | Journal Article
Abstract 17134: Variation Within a Left Ventricle-Specific Hand1 Enhancer Impairs Gata Transcription Factor Binding and Disrupts Ventricular Conduction System Development
Vincentz, JoshuaFirulli, BethToolan, KevinArking, DanSotoodehnia, NonaWan, JuyiChen, Peng-Shengde Gier-de Vries, CorrieChristoffels, VincentRubart-von der Lohe, Michael and Firulli, Anthony
Circulation, vol. 138, (no. Suppl_1 Suppl 1), pp. A17134, 2018-November-6. | Journal Article
Notch signaling regulates Hey2 expression in a spatiotemporal dependent manner during cardiac morphogenesis and trabecular specification
Miao, LianjieLi, JingjingLi, JunTian, XueyingLu, YangyangHu, SaiyangShieh, DavidKanai, RyanZhou, Bo-YangZhou, BinLiu, JiandongFirulli, Anthony BMartin, James FSinger, HaroldZhou, BinXin, Hongbo and Wu, Mingfu
Scientific reports, vol. 8, (no. 1), pp. 14, 2018-02-08. | Journal Article
Defective Hand1 phosphoregulation uncovers essential roles for Hand1 in limb morphogenesis
Firulli, Beth AFirulli, Beth AMilliar, HannahMilliar, HannahToolan, Kevin PToolan, Kevin PHarkin, JadeHarkin, JadeFuchs, Robyn KFuchs, Robyn KRobling, Alex GRobling, Alex GFirulli, Anthony B and Firulli, Anthony B
Development (Cambridge, England), vol. 144, (no. 13), pp. 2489, 2017-07-01. | Journal Article
Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function
Vincentz, Joshua WToolan, Kevin PZhang, Wenjun and Firulli, Anthony B
PLoS genetics, vol. 13, (no. 7), pp. e1006922, 2017-Jul. | Journal Article
Nkx2.5 regulates endothelin converting enzyme‐1 during pharyngeal arch patterning
Iklé, J.M.Iklé, Jennifer MIklé, Jennifer MTavares, Andre L. PTavares, A.L.P.Tavares, Andre LKing, MarisolKing, M.King, MarisolDing, HaileiDing, HaileiDing, H.Colombo, S.Colombo, SophieColombo, SophieFirulli, B.A.Firulli, Beth AFirulli, Beth AFirulli, Anthony BFirulli, Anthony BFirulli, A.B.Targoff, Kimara LTargoff, Kimara LTargoff, K.L.Yelon, DeborahYelon, D.Yelon, DeborahClouthier, D.E.Clouthier, David E and Clouthier, David E
genesis, vol. 55, (no. 3), pp. n/a, March 2017. | Journal Article
The HAND1 frameshift A126FS mutation does not cause hypoplastic left heart syndrome in mice
Firulli, Beth AToolan, Kevin PHarkin, JadeMillar, HannahPineda, Santiago and Firulli, Anthony B
Cardiovascular research, vol. 113, (no. 14), pp. 1742, 2017-Dec-01. | Journal Article
Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap
Vincentz, JoshuaCasasnovas, JoseBarnes, RalstonQue, JianwenClouthier, DavidWang, Jun and Firulli, Anthony
Proceedings of the National Academy of Sciences of the United States of America, vol. 113, (no. 27), pp. 7568, 20160705. | Journal Article
Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification
Li, JingjingLi, JingjingMiao, LianjieMiao, LianjieShieh, DavidShieh, DavidSpiotto, ErnestSpiotto, ErnestLi, JianLi, JianZhou, BinZhou, BinPaul, AntoniPaul, AntoniSchwartz, Robert JSchwartz, Robert JFirulli, Anthony BFirulli, Anthony BSinger, Harold ASinger, Harold AHuang, GuoyingHuang, GuoyingWu, Mingfu and Wu, Mingfu
Cell Reports, vol. 15, (no. 1), pp. 170, 2016-04-05. | Journal Article
Hand1 phosphoregulation within the distal arch neural crest is essential for craniofacial morphogenesis
Firulli, Beth AFirulli, Beth AFuchs, Robyn KFuchs, Robyn KVincentz, Joshua WVincentz, Joshua WClouthier, David EClouthier, David EFirulli, Anthony B and Firulli, Anthony B
Development (Cambridge, England), vol. 141, (no. 15), pp. 3061, 2014-Aug. | Journal Article
Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration
Schindler, Yocheved LSchindler, Yocheved LGarske, Kristina MGarske, Kristina MWang, JinhuWang, JinhuFirulli, Beth AFirulli, Beth AFirulli, Anthony BFirulli, Anthony BPoss, Kenneth DPoss, Kenneth DYelon, Deborah and Yelon, Deborah
Development (Cambridge, England), vol. 141, (no. 16), pp. 3122, 2014-Aug. | Journal Article