113 Publications (Page 3 of 5)
2002
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro.
Galli, AndreaCrabb, David WCeni, ElisabettaSalzano, RenataMello, TommasoSvegliati-Baroni, GianlucaRidolfi, FrancescoTrozzi, LucianoSurrenti, Calogero and Casini, Alessandro
Gastroenterology, vol. 122, (no. 7), pp. 1924-40, 2002/Jun. | Journal Article
 
Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP).
You, MinFischer, MonikaDeeg, Mark A and Crabb, David W
The Journal of biological chemistry. , vol. 277, (no. 32), pp. 29342-7, 2002/Aug/9. | Journal Article
 
Transcriptional control of the human aldehyde dehydrogenase 2 promoter by hepatocyte nuclear factor 4: inhibition by cyclic AMP and COUP transcription factors.
You, MinFischer, MonikaCho, Won K and Crabb, David
Archives of biochemistry and biophysics, vol. 398, (no. 1), pp. 79-86, 2002/Feb/1. | Journal Article
2001
Alcohol and retinoids.
Crabb, David WPinairs, JHasanadka, RFang, MLeo, M ALieber, C STsukamoto, HMotomura, KMiyahara, TOhata, MBosron, WSanghani, SKedishvili, NShiraishi, HYokoyama, HMiyagi, MIshii, HBergheim, IMenzl, IParlesak, A and Bode, C
Alcoholism, clinical and experimental research. , vol. 25, (no. 5 Suppl ISBRA), pp. 207S-217S, 2001/May. | Journal Article
 
Alcohol and retinoids.
Crabb, D WPinairs, JHasanadka, RFang, MLeo, M ALieber, C STsukamoto, HMotomura, KMiyahara, TOhata, MBosron, WSanghani, SKedishvili, NShiraishi, HYokoyama, HMiyagi, MIshii, HBergheim, IMenzl, IParlesak, A and Bode, C
Alcoholism, clinical and experimental research, vol. 25, (no. 5 Suppl ISBRA), pp. 207S-217S, May 2001. | Journal Article
 
Alcoholic liver disease.
Lumeng, Lawrence and Crabb, David W
Current opinion in gastroenterology, vol. 17, (no. 3), pp. 211-20, 2001/May. | Journal Article
 
Genetic and environmental influences on alcohol metabolism in humans.
Li, Ting KaiYin, S JCrabb, David WO'Connor, S and Ramchandani, Vijay A
Alcoholism, clinical and experimental research, vol. 25, (no. 1), pp. 136-44, 2001/Jan. | Journal Article
 
Peroxisome proliferator-activated receptors (PPAR) and the mitochondrial aldehyde dehydrogenase (ALDH2) promoter in vitro and in vivo.
Crabb, David WPinaire, JChou, W YSissom, SPeters, Jeffrey MHarris, R A and Stewart, M
Alcoholism, clinical and experimental research. , vol. 25, (no. 7), pp. 945-52, 2001/Jul. | Journal Article
 
The Transcriptional and DNA Binding Activity of Peroxisome Proliferator-activated Receptor alpha Is Inhibited by Ethanol Metabolism A NOVEL MECHANISM FOR THE DEVELOPMENT OF ETHANOL-INDUCED FATTY LIVER
Galli, A.Pinaire, J.Fischer, M.Dorris, R. and Crabb, David W
Journal of Biological Chemistry, vol. 276, (no. 1), pp. 68-75, 2001. | Journal Article
2000
Alcoholic liver disease.
Lumeng, Lawrence and Crabb, David W
Current opinion in gastroenterology, vol. 16, (no. 3), pp. 208-18, 2000/May. | Journal Article
 
Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells.
Galli, ACrabb, David WPrice, DCeni, ESalzano, RSurrenti, C and Casini, A
Hepatology (Baltimore, Md.), vol. 31, (no. 1), pp. 101-8, 2000/Jan. | Journal Article
 
The retinoid X receptor response element in the human aldehyde dehydrogenase 2 promoter is antagonized by the chicken ovalbumin upstream promoter family of orphan receptors.
Pinaire, JHasanadka, RFang, MicheleChou, W YStewart, Mark JKruijer, W and Crabb, David W
Archives of biochemistry and biophysics, vol. 380, (no. 1), pp. 192-200, 2000/Aug/1. | Journal Article
 
The role of hepatic peroxisome proliferator-activated receptors (PPARs) in health and disease.
Everett, LGalli, A and Crabb, D
Liver, vol. 20, (no. 3), pp. 191-199, June 2000. | Journal Article
1999
Alcohol and medication interactions
Crabb, David W
(pp. 40-54). 1999
 
Alcohol and medication interactions.
Weathermon, R and Crabb, David W
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, vol. 23, (no. 1), pp. 40-54, 1999. | Journal Article
 
An A/G polymorphism in the promoter of mitochondrial aldehyde dehydrogenase (ALDH2): effects of the sequence variant on transcription factor binding and promoter strength.
Chou, W YStewart, Mark JCarr, L GZheng, DStewart, T RWilliams, APinaire, J and Crabb, David W
Alcoholism, clinical and experimental research, vol. 23, (no. 6), pp. 963-8, 1999/Jun. | Journal Article
 
Pathogenesis of alcoholic liver disease: newer mechanisms of injury.
Crabb, David W
The Keio journal of medicine, vol. 48, (no. 4), pp. 184-8, 1999/Dec. | Journal Article
 
Sensitivity of virally-driven luciferase reporter plasmids to members of the steroid/thyroid/retinoid family of nuclear receptors
Everett, LM and Crabb, David W
Journal of Steroid Biochemistry and Molecular Biology, vol. 70, (no. 4-6), pp. 197-201, 1999. | Journal Article
1998
Binding and activation of the human aldehyde dehydrogenase 2 promoter by hepatocyte nuclear factor 4.
Stewart, Mark JDipple, Katrina MEstonius, MatsNakshatri, HEverett, L M and Crabb, David W
Biochimica et biophysica acta, vol. 1399, (no. 2-3), pp. 181-6, 1998/Aug/20. | Journal Article
 
High-level expression of RXRalpha and the presence of endogenous ligands contribute to expression of a peroxisome proliferator-activated receptor-responsive gene in hepatoma cells.
Galli, AStewart, MDorris, R and Crabb, David W
Archives of biochemistry and biophysics, vol. 354, (no. 2), pp. 288-94, 1998/Jun/15. | Journal Article
 
Studies on the enzymology of aldehyde dehydrogenase-2 in genetically modified HeLa cells.
Crabb, D and Xiao, Q
Alcoholism, clinical and experimental research, vol. 22, (no. 4), pp. 780-781, June 1998. | Journal Article
1997
A direct repeat (DR-1) element in the first exon modulates transcription of the preproenkephalin A gene
Chan, Rebecca MStewart, Mark J and Crabb, David W
Molecular Brain Research, vol. 45, (no. 1), pp. 50-58, 1997. | Journal Article
 
First pass metabolism of ethanol: gastric or hepatic, mountain or molehill?
Crabb, David W
Hepatology (Baltimore, Md.), vol. 25, (no. 5), pp. 1292-4, 1997/May. | Journal Article
 
Structural and mechanistic aspects of a new family of dehydrogenases, the beta-hydroxyacid dehydrogenases.
Hawes, John WHarper, Edwin TCrabb, David W and Harris, R A
Advances in experimental medicine and biology, vol. 414, pp. 395-402, 1997. | Journal Article
 
Studies on the dominant negative effect of the ALDH2*2 allele.
Xiao, QWeiner, Henry and Crabb, David W
Advances in experimental medicine and biology, vol. 414, pp. 187-94, 1997. | Journal Article