110 Publications (Page 2 of 5)
2017
Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form
Collier, Timothy J⋅Srivastava, Kinshuk R⋅Justman, Craig⋅Grammatopoulous, Tom⋅Hutter-Paier, Birgit⋅Prokesch, Manuela⋅Havas, Daniel⋅Rochet, Jean-Christophe⋅Liu, Fang⋅Jock, Kevin⋅de Oliveira, Patrícia⋅Stirtz, Georgia L⋅Dettmer, Ulf⋅Sortwell, Caryl E⋅Feany, Mel B⋅Lansbury, Peter⋅Lapidus, Lisa and Paumier, Katrina L
Neurobiology of Disease, vol. 106, pp. 204, October 2017. | Journal Article
 
Pikuni-Blackfeet traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms.
de Rus Jacquet, Aurélie⋅Tambe, Mitali Arun⋅Ma, Sin Ying⋅McCabe, George P⋅Vest, Jay Hansford C and Rochet, Jean-Christophe
Journal of ethnopharmacology, January 11, 2017. | Journal Article
 
β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease
Mittal, Shuchi⋅Mittal, Shuchi⋅Bjornevik, Kjetil⋅Bjørnevik, Kjetil⋅Im, Doo Soon⋅Im, Doo Soon⋅Flierl, Adrian⋅Flierl, Adrian⋅Dong, Xianjun⋅Dong, Xianjun⋅Locascio, Joseph J.⋅Locascio, Joseph J⋅Abo, Kristine M⋅Abo, Kristine M.⋅Long, Elizabeth⋅Long, Elizabeth⋅Jin, Ming⋅Jin, Ming⋅Xu, Bing⋅Xu, Bing⋅al.⋅Xiang, Yang K⋅Rochet, Jean-Christophe⋅Engeland, Anders⋅Rizzu, Patrizia⋅Heutink, Peter⋅Bartels, Tim⋅Selkoe, Dennis J⋅Caldarone, Barbara J⋅Glicksman, Marcie A⋅Khurana, Vikram⋅Schüle, Birgitt⋅Park, David S⋅Riise, Trond and Scherzer, Clemens R
Science (New York, N.Y.), vol. 357, (no. 6354), pp. 898, 2017-09-01. | Journal Article
2016
Effect of Acidic pH on the Stability of Alpha-Synuclein Dimers
Lv, Zhengjian⋅Krasnoslobodtsev, Alexey V⋅Zhang, Yuliang⋅Ysselstein, Daniel⋅Rochet, Jean-Christophe⋅Blanchard, Scott C and Lyubchenko, Yuri L
Biophysical Journal, vol. 110, (no. 3), pp. 552a, 2016-02-16. | Journal Article
 
Printed optics: phantoms for quantitative deep tissue fluorescence imaging
Bentz, Brian Z⋅Bentz, Brian Z⋅Bentz, Brian Z⋅Bowen, Anna G⋅Bowen, Anna G⋅Bowen, Anna G⋅Lin, Dergan⋅Lin, Dergan⋅Lin, Dergan⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Huston, Davin H⋅Huston, Davin H⋅Huston, Davin H⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Webb, Kevin J⋅Webb, Kevin J and Webb, Kevin J
Optics letters, vol. 41, (no. 22), pp. 5233, 2016-Nov-15. | Journal Article
 
Printed optics: phantoms for quantitative deep tissue fluorescence imaging: publisher's note
Bentz, Brian Z⋅Bentz, Brian Z⋅Bentz, Brian Z⋅Bowen, Anna G⋅Bowen, Anna G⋅Bowen, Anna G⋅Lin, Dergan⋅Lin, Dergan⋅Lin, Dergan⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Huston, Davin H⋅Huston, Davin H⋅Huston, Davin H⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Webb, Kevin J⋅Webb, Kevin J and Webb, Kevin J
Optics letters, vol. 41, (no. 23), pp. 5575, 2016-Dec-01. | Journal Article
2015
Cu(II) promotes amyloid pore formation
Zhang, Hangyu⋅Rochet, Jean-Christophe and Stanciu, Lia A
Biochemical and Biophysical Research Communications, vol. 464, (no. 1), pp. 347, 2015-08-14. | Journal Article
 
Direct Detection of [alpha]-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis
Lv, Zhengjian⋅Krasnoslobodtsev, Alexey⋅Zhang, Yuliang⋅Ysselstein, Daniel⋅Rochet, Jean-Christophe⋅Blanchard, Scott and Lyubchenko, Yuri
Biophysical Journal, vol. 108, (no. 8), pp. 2038, 20150421. | Journal Article
 
Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis
Lv, Zhengjian⋅Lv, Zhengjian⋅Krasnoslobodtsev, Alexey V⋅Krasnoslobodtsev, Alexey V⋅Zhang, Yuliang⋅Zhang, Yuliang⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Blanchard, Scott C⋅Blanchard, Scott C⋅Lyubchenko, Yuri L and Lyubchenko, Yuri L
Biophysical Journal, vol. 108, (no. 8), pp. 2047, 2015-04-21. | Journal Article
 
Effects of impaired membrane interactions on α-synuclein aggregation and neurotoxicity.
Ysselstein, Daniel⋅Ysselstein, Daniel⋅Joshi, Mehul⋅Joshi, Mehul⋅Mishra, Vartika⋅Mishra, Vartika⋅Griggs, Amy⋅Griggs, Amy M⋅Asiago, Josephat⋅Asiago, Josephat M⋅Mc Cabe, George P⋅McCabe, George⋅Stanciu, Lia⋅Stanciu, Lia A⋅Post, Carol⋅Post, Carol Beth⋅Rochet, Jean-Christophe and Rochet, Jean-Christophe
Neurobiology of disease, vol. 79, pp. 150-163, July 2015. | Journal Article
 
Expression and Transport of α-Synuclein at the Blood-Cerebrospinal Fluid Barrier and Effects of Manganese Exposure
Bates, Christopher A⋅Fu, Sherleen⋅Ysselstein, Daniel⋅Rochet, Jean-Christophe and Zheng, Wei
ADMET & DMPK, vol. 3, (no. 1), pp. 33, 2015. | Journal Article
 
Hsp31 Is a Stress Response Chaperone That Intervenes in the Protein Misfolding Process
Tsai, Chai-Jui⋅Tsai, Chai-Jui⋅Aslam, Kiran⋅Aslam, Kiran⋅Drendel, Holli M⋅Drendel, Holli M⋅Asiago, Josephat M⋅Asiago, Josephat M⋅Goode, Kourtney M⋅Goode, Kourtney M⋅Paul, Lake N⋅Paul, Lake N⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Hazbun, Tony R and Hazbun, Tony R
The Journal of biological chemistry, vol. 290, (no. 41), pp. 24834, 2015-Oct-09. | Journal Article
 
Single Molecule Fluorescence Assay of Alpha Synuclein Dimerization
Lv, Zhengjian⋅Krasnoslobodtsev, Alexey V⋅Zhang, Yuliang⋅Ysselstein, Daniel⋅Rochet, Jean-Christophe⋅Blanchard, Scott and Lyubchenko, Yuri L
Biophysical Journal, vol. 108, (no. 2), pp. 63a, 2015-01-27. | Journal Article
2014
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is selectively toxic to primary dopaminergic neurons in vitro.
Griggs, Amy M⋅Agim, Zeynep S⋅Mishra, Vartika R⋅Tambe, Mitali A⋅Director-Myska, Alison E⋅Turteltaub, Kenneth W⋅Mc Cabe, George P⋅Rochet, Jean-Christophe and Cannon, Jason R
Toxicological sciences : an official journal of the Society of Toxicology, vol. 140, (no. 1), pp. 179-189, July 2014. | Journal Article
 
Combinatorial Polarized TIRF-AFM Study of Membrane Reorganization by Alpha-Synuclein and Human Prion Protein
Kurylowicz, Martin⋅Vanderlee, Gillian⋅Ysselstein, Daniel⋅Walsh, Patrick⋅Yau, Jason⋅Sharpe, Simon⋅Rochet, Jean-Christophe and Yip, Christopher M
Biophysical Journal, vol. 106, (no. 2), pp. 302a, 2014-01-28. | Journal Article
 
Nepalese traditional medicine and symptoms related to Parkinsonx[superscript three]s disease and other disorders: Patterns of the usage of plant resources along the Himalayan altitudinal range
Jacquet, AureLie⋅Subedi, Rupa⋅Ghimire, Suresh and Rochet, Jean-Christophe
Journal of Ethnopharmacology, vol. 153, (no. 1), pp. 178, 20140411. | Journal Article
 
Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease.
Strathearn, Katherine E⋅Yousef, Gad⋅Grace, Mary⋅Roy, Susan L⋅Tambe, Mitali A⋅Ferruzzi, Mario G⋅Wu, Qing-Li⋅Simon, James E⋅Lila, Mary A and Rochet, Jean-Christophe
Brain research, vol. 1555, pp. 60-77, 2014/Mar/25. | Journal Article
 
Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways
Anandhan, A.⋅Anandhan, Annadurai⋅Rodriguez-Rocha, H.⋅Rodriguez-Rocha, Humberto⋅Bohovych, I.⋅Bohovych, Iryna⋅Griggs, A.M.⋅Griggs, Amy⋅Zavala Flores, L.⋅Zavala-Flores, Laura⋅Reyes-Reyes, E.M.⋅Reyes-Reyes, Elsa⋅Seravalli, J.⋅Seravalli, Javier⋅Stanciu, Lia⋅Stanciu, L.A.⋅Lee, J.⋅Lee, Jaekwon⋅Rochet, J.-C.⋅Rochet, Jean-Christophe⋅Khalimonchuk, O.⋅Khalimonchuk, Oleh⋅Franco, R. and Franco, Rodrigo
Neurobiology of Disease, vol. 81, pp. 92, 2014. | Journal Article
 
Targeting the Intrinsically Disordered Structural Ensemble of [alpha]-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson's Disease
Tóth, Gergely⋅Toth, Gergely⋅Gardai, Shyra⋅Gardai, Shyra J⋅Zago, Wagner⋅Zago, Wagner⋅Bertoncini, Carlos W⋅Bertoncini, Carlos⋅Cremades, Nunilo⋅Cremades, Nunilo⋅Roy, Susan⋅Roy, Susan L⋅Tambe, Mitali A⋅Tambe, Mitali⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Galvagnion, Celine⋅Galvagnion, Celine⋅Skibinski, Gaia⋅Skibinski, Gaia⋅Finkbeiner, Steven⋅Finkbeiner, Steven⋅Bova, Michael⋅Bova, Michael⋅Regnstrom, Karin⋅Regnstrom, Karin⋅Chiou, San-San⋅Chiou, San-San⋅Johnston, Jennifer⋅Johnston, Jennifer⋅Callaway, Kari⋅Callaway, Kari⋅Anderson, John⋅Anderson, John P⋅Jobling, Michael⋅Jobling, Michael F⋅Buell, Alexander K⋅Buell, Alexander⋅Yednock, Ted A⋅Yednock, Ted⋅Knowles, Tuomas⋅Knowles, Tuomas P⋅Vendruscolo, Michele⋅Vendruscolo, Michele⋅Christodoulou, John⋅Christodoulou, John⋅Dobson, Christopher M⋅Dobson, Christopher⋅Schenk, Dale⋅Schenk, Dale⋅McConlogue, Lisa and McConlogue, Lisa
PLoS ONE, vol. 9, (no. 2), pp. e87133, 20140214. | Journal Article
2013
In Vitro Study of [alpha]-Synuclein Protofibrils by Cryo-EM Suggests a Cu^sup 2+^-Dependent Aggregation Pathway
Zhang, Hangyu⋅Griggs, Amy⋅Rochet, Jean-Christophe and Stanciu, Lia
Biophysical Journal, vol. 104, (no. 12), pp. 2706, 20130618. | Journal Article
 
In vitro study of α-synuclein protofibrils by cryo-EM suggests a Cu(2+)-dependent aggregation pathway
Zhang, Hangyu⋅Griggs, Amy⋅Rochet, Jean-Christophe and Stanciu, Lia A
Biophysical journal, vol. 104, (no. 12), pp. 2706, 2013-Jun-18. | Journal Article
 
In Vitro Study of α-Synuclein Protofibrils by Cryo-EM Suggests a Cu2+-Dependent Aggregation Pathway
Zhang, Hangyu⋅Griggs, Amy⋅Rochet, Jean-Christophe and Stanciu, Lia A
Biophysical Journal, vol. 104, (no. 12), pp. 2713, 2013-06-18. | Journal Article
 
Reusable photocatalytic titanium dioxide–cellulose nanofiber films
Snyder, Alexandra⋅Bo, Zhenyu⋅Moon, Robert⋅Rochet, Jean-Christophe and Stanciu, Lia
Journal of Colloid And Interface Science, vol. 399, pp. 98, 2013-06-01. | Journal Article
 
Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons.
Tardiff, Daniel F⋅Jui, Nathan T⋅Khurana, Vikram⋅Tambe, Mitali A⋅Thompson, Michelle L⋅Chung, Chee Y⋅Kamadurai, Hari B⋅Kim, Hyoung T⋅Lancaster, Alex⋅Caldwell, Kim A⋅Caldwell, Guy⋅Rochet, Jean-Christophe⋅Buchwald, Stephen L and Lindquist, Susan
Science (New York, N.Y.), vol. 342, (no. 6161), pp. 979-83, 2013/Nov/22. | Journal Article
 
α‑Synuclein Misfolding Assessed with Single Molecule AFM Force Spectroscopy: Effect of Pathogenic Mutations
Krasnoslobodtsev, Alexey V⋅Volkov, Ivan L⋅Asiago, Josephat M⋅Hindupur, Jagadish⋅Rochet, Jean-Christophe and Lyubchenko, Yuri L
Biochemistry, vol. 52, (no. 42), pp. 7386, 20131022. | Journal Article