23 Publications
2019
Timing s everything in light, location, and cells.
Blood. | Journal Article
2017
DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms
O’leary, Heather Ann⋅O’leary, Heather Ann⋅O’leary, Heather Ann⋅O’Leary, H A⋅Capitano, M⋅Capitano, Maegan⋅Capitano, Maegan⋅Capitano, Maegan⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, S⋅Cooper, Scott⋅Mantel, Charlie⋅Mantel, Charlie⋅Mantel, C⋅Mantel, Charlie⋅Boswell, H. Scott⋅Boswell, H. Scott⋅Boswell, H S⋅Boswell, H. Scott⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, R⋅Ramdas, B⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Chan, Rebecca⋅Chan, R⋅Chan, Rebecca⋅Chan, Rebecca⋅Deng, Lisa⋅Deng, Lisa⋅Deng, Lisa⋅Deng, L⋅Qu, Cheng-Kui⋅Qu, Cheng-Kui⋅Qu, Cheng-Kui⋅Qu, C-K⋅Broxmeyer, H E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E and Broxmeyer, Hal E
Leukemia, vol. 31, pp. 2468–2478. | Journal Article
 
High-dose sitagliptin for systemic inhibition of dipeptidylpeptidase-4 to enhance engraftment of single cord umbilical cord blood transplantation
Farag, Sherif S⋅Farag, Sherif S⋅Farag, Sherif S⋅Farag, Sherif S.⋅Farag, Sherif S⋅Farag, Sherif S⋅Farag, Sherif S⋅Farag, Sherif S⋅Nelson, Robert⋅Nelson, Robert⋅Nelson, Robert⋅Nelson, Robert⋅Nelson, Robert⋅Nelson, Robert⋅Nelson, Robert⋅Nelson, Robert⋅Cairo, Mitchell S⋅Cairo, Mitchell S⋅Cairo, Mitchell S⋅Cairo, Mitchell S⋅Cairo, Mitchell S⋅Cairo, Mitchell S⋅Cairo, Mitchell S⋅Cairo, Mitchell S.⋅O’Leary, Heather A.⋅O'Leary, Heather A⋅O'Leary, Heather A⋅O'Leary, Heather A⋅O'Leary, Heather A⋅O'Leary, Heather A⋅O'Leary, Heather A⋅O'Leary, Heather A⋅Zhang, Shuhong⋅Zhang, Shuhong⋅Zhang, Shuhong⋅Zhang, Shuhong⋅Zhang, Shuhong⋅Zhang, Shuhong⋅Zhang, Shuhong⋅Zhang, Shuhong⋅Huntley, Carol⋅Huntley, Carol⋅Huntley, Carol⋅Huntley, Carol⋅Huntley, Carol⋅Huntley, Carol⋅Huntley, Carol⋅Huntley, Carol⋅Delgado, David⋅Delgado, David⋅Delgado, David⋅Delgado, David⋅Delgado, David⋅Delgado, David⋅Delgado, David⋅Delgado, David⋅Schwartz, Jennifer⋅Schwartz, Jennifer⋅Schwartz, Jennifer⋅Schwartz, Jennifer⋅Schwartz, Jennifer⋅Schwartz, Jennifer⋅Schwartz, Jennifer⋅Schwartz, Jennifer⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Abonour, Rafat⋅Abonour, Rafat⋅Abonour, Rafat⋅Abonour, Rafat⋅Abonour, Rafat⋅Abonour, Rafat⋅Abonour, Rafat⋅Abonour, Rafat⋅Robertson, Michael⋅Robertson, Michael⋅Robertson, Michael⋅Robertson, Michael⋅Robertson, Michael⋅Robertson, Michael⋅Robertson, Michael⋅Robertson, Michael⋅Broxmeyer, Hal⋅Broxmeyer, Hal⋅Broxmeyer, Hal⋅Broxmeyer, Hal⋅Broxmeyer, Hal⋅Broxmeyer, Hal⋅Broxmeyer, Hal and Broxmeyer, Hal
Oncotarget, vol. 8. | Journal Article
 
Utility of CRISPR/Cas9 systems in hematology research.
Experimental hematology. | Journal Article
2016
508. IL-33/ST2 Triggering of IL-9-Secreting T Cells: From Proteomics to Therapeutics
Ramadan, Abdulraouf⋅Ramadan, Abdulraouf⋅Ramadan, Abdulraouf⋅Ramadan, Abdulraouf⋅Ramadan, Abdulraouf⋅Zhang, Jilu⋅Zhang, Jilu⋅Zhang, Jilu⋅Zhang, Jilu⋅Zhang, Jilu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Zaid, Mohammad Abu⋅Taylor, Lauren⋅Taylor, Lauren⋅Taylor, Lauren⋅Taylor, Lauren⋅Taylor, Lauren⋅O'Leary, Heather A⋅O'Leary, Heather A⋅O'Leary, Heather A⋅O'Leary, Heather A⋅O’Leary, Heather A.⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E.⋅Broxmeyer, Hal E⋅Kaplan, Mark H.⋅Kaplan, Mark H⋅Kaplan, Mark H⋅Kaplan, Mark H⋅Kaplan, Mark H⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Paczesny, Sophie⋅Paczesny, Sophie and Paczesny, Sophie
Molecular Therapy, vol. 24, pp. S202–S203. | Journal Article
 
Dipeptidyl peptidase 4 (DPP4) truncated factors manifest distinct regulatory functions compared to their full length forms and DPP4 is altered by, and modulates stem cell response to, extra physiologic oxygen shock/stress (EPHOSS)
O'Leary, Heather⋅O’Leary, Heather⋅Jiang, Guanglong⋅Jiang, Guanglong⋅Lai, Xianyin⋅Lai, Xianyin⋅McNamara, Tom⋅McNamara, Tom⋅Li, Sujun⋅Li, Sujun⋅Mantel, Charlie⋅Mantel, Charlie⋅Cooper, Scott⋅Cooper, Scott⋅Hangoc, Giao⋅Hangoc, Giao⋅Lee, ManRyul⋅Lee, ManRyul⋅Boswell, H.⋅Boswell, H. Scott⋅Witzmann, Frank⋅Witzmann, Frank⋅Li, Lang⋅Li, Lang⋅Broxmeyer, Hal and Broxmeyer, Hal
Experimental Hematology, vol. 44, pp. S93–S94. | Journal Article
 
ID: 95: IL-33/ST2 TRIGGERING OF IL-9–SECRETING T CELLS: FROM PROTEOMICS TO THERAPEUTICS
Ramadan, A⋅Zhang, J⋅Zaid, M Abu⋅Taylor, L⋅O’Leary, H⋅Kapur, R⋅Hanenberg, H⋅Broxmeyer, HE⋅Kaplan, MH and Paczesny, S
Journal of Investigative Medicine, vol. 64, pp. 948.1–948. | Journal Article
2015
Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock
Mantel, Charlie R⋅Mantel, Charlie R.⋅Mantel, Charlie R⋅Mantel, Charlie R⋅O’Leary, Heather A.⋅O'Leary, Heather A⋅O’Leary, Heather A⋅O’Leary, Heather A⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R.⋅Huang, XinXin⋅Huang, Xin Xin⋅Huang, XinXin⋅Huang, XinXin⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Hangoc, Giao⋅Hangoc, Giao⋅Hangoc, Giao⋅Hangoc, Giao⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Srour, Edward F⋅Srour, Edward F.⋅Srour, Edward F⋅Srour, Edward F⋅Lee, Man Ryul⋅Lee, Man Ryul⋅Lee, Man Ryul⋅Lee, Man Ryul⋅Messina-Graham, Steven⋅Messina-Graham, Steven⋅Messina-Graham, Steven⋅Messina-Graham, Steven⋅Haas, David M⋅Haas, David M⋅Haas, David M.⋅Haas, David M⋅Falah, Nadia⋅Falah, Nadia⋅Falah, Nadia⋅Falah, Nadia⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M.⋅Pelus, Louis M⋅Bardeesy, Nabeel⋅Bardeesy, Nabeel⋅Bardeesy, Nabeel⋅Bardeesy, Nabeel⋅Fitamant, Julien⋅Fitamant, Julien⋅Fitamant, Julien⋅Fitamant, Julien⋅Ivan, Mircea⋅Ivan, Mircea⋅Ivan, Mircea⋅Ivan, Mircea⋅Kim, Kye-Seong⋅Kim, Kye-Seong⋅Kim, Kye-Seong⋅Kim, Kye-Seong⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E.⋅Broxmeyer, Hal E and Broxmeyer, Hal E
Cell, vol. 161, pp. 1553–1565. | Journal Article
 
The importance of hypoxia and extra physiologic oxygen shock/stress for collection and processing of stem and progenitor cells to understand true physiology/pathology of these cells ex vivo
Broxmeyer, Hal E⋅Broxmeyer, Hal⋅Broxmeyer, Hal E.⋅O’Leary, Heather⋅O Leary, Heather A⋅O’Leary, Heather A.⋅Huang, Xinxin⋅Huang, Xinxin⋅Huang, Xinxin⋅Mantel, Charlie⋅Mantel, Charlie and Mantel, Charlie
Current Opinion in Hematology, pp. 1. | Journal Article
2014
DPP4 regulates in vitro and in vivo hematopoiesis mediated by myelosuppressive chemokines
Broxmeyer, Hal⋅Broxmeyer, Hal⋅Cooper, Scott⋅Cooper, Scott⋅Campbell, Timothy⋅Campbell, Timothy⋅O'Leary, Heather⋅O’Leary, Heather⋅Hangoc, Giao and Hangoc, Giao
Experimental Hematology, vol. 42, pp. S25. | Journal Article
 
DPP4 truncation alters the signaling and functional activity of GM-CSF and LL-3 in normal and leukemic hematopoietic cells
O'Leary, Heather⋅O’Leary, Heather⋅Mantel, Charlie⋅Mantel, Charlie⋅Lee, Man⋅Lee, Man Ryul⋅Lai, Xianyin⋅Lai, Xianyin⋅Cooper, Scott⋅Cooper, Scott⋅Hangoc, Giao⋅Hangoc, Giao⋅Boswell, H. Scott⋅Boswell, H.⋅Broxmeyer, Hal and Broxmeyer, Hal
Experimental Hematology, vol. 42, pp. S55. | Journal Article
2013
Concise review: role of DEK in stem/progenitor cell biology. Stem cells (Dayton, Ohio)
Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Mor-Vaknin, Nirit⋅Mor‐Vaknin, Nirit⋅Kappes, Ferdinand⋅Kappes, Ferdinand⋅Legendre, Maureen⋅Legendre, Maureen⋅Saha, Anjan K⋅Saha, Anjan K⋅Ou, Xuan⋅Ou, Xuan⋅O'Leary, Heather⋅O'Leary, Heather⋅Capitano, Maegan⋅Capitano, Maegan⋅Cooper, Scott⋅Cooper, Scott⋅Markovitz, David M and Markovitz, David
Stem cells (Dayton, Ohio). | Journal Article
 
Contribution of electromechanical coupling between Kv and Ca v1.2 channels to coronary dysfunction in obesity.
Berwick, Zachary⋅Berwick, Zachary⋅Berwick, Z.C.⋅Berwick, Zachary C⋅Dick, Gregory⋅Dick, Gregory⋅Dick, G.M.⋅Dick, Gregory M⋅O'Leary, Heather A⋅O’Leary, H.A.⋅O’Leary, Heather⋅O’Leary, Heather⋅Bender, Shawn⋅Bender, Shawn B⋅Bender, Shawn⋅Bender, S.B.⋅Goodwill, Adam G⋅Goodwill, Adam⋅Goodwill, Adam⋅Goodwill, A.G.⋅Moberly, S.P.⋅Moberly, Steven⋅Moberly, Steven⋅Moberly, Steven P⋅Owen, Meredith⋅Owen, Meredith K⋅Owen, M.K.⋅Owen, Meredith⋅Miller, Steven⋅Miller, Steven⋅Miller, S.J.⋅Miller, Steven J⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Obukhov, A.G.⋅Obukhov, Alexander G⋅Tune, J.D.⋅Tune, Johnathan⋅Tune, Johnathan and Tune, Johnathan D
Basic research in cardiology. | Journal Article
 
Implications of DPP4 modification of proteins that regulate stem/progenitor and more mature cell types
Ou, Xuan⋅Ou, X.⋅O'Leary, Heather A⋅O’Leary, H. A.⋅Broxmeyer, Hal E and Broxmeyer, H. E.
Blood, vol. 122, pp. 161–169. | Journal Article
 
The role of dipeptidyl peptidase 4 in hematopoiesis and transplantation
O'Leary, Heather⋅O’Leary, Heather⋅Ou, Xuan⋅Ou, Xuan⋅Broxmeyer, Hal E and Broxmeyer, Hal E.
Current Opinion in Hematology, vol. 20, pp. 314–319. | Journal Article
2012
Bone marrow osteoblast damage by chemotherapeutic agents.
Rellick, Stephanie L⋅Rellick, Stephanie L⋅O'Leary, Heather⋅O'Leary, Heather⋅Piktel, Debbie⋅Piktel, Debbie⋅Walton, Cheryl⋅Walton, Cheryl⋅Fortney, James E⋅Fortney, James E⋅Akers, Stephen M⋅Akers, Stephen M⋅Martin, Karen H⋅Martin, Karen H⋅Denvir, James⋅Denvir, James⋅Boskovic, Goran⋅Boskovic, Goran⋅Primerano, Donald A⋅Primerano, Donald A⋅Vos, Jeffrey⋅Vos, Jeffrey⋅Bailey, Nathanael⋅Bailey, Nathanael G⋅Gencheva, Marieta⋅Gencheva, Marieta⋅Gibson, Laura F and Gibson, Laura F
PloS one. | Journal Article
 
Dipeptidylpeptidase 4 negatively regulates colony-stimulating factor activity and stress hematopoiesis
Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Hoggatt, Jonathan⋅Hoggatt, Jonathan⋅Hoggatt, Jonathan⋅O'leary, Heather A⋅O'leary, Heather A⋅O'Leary, Heather A⋅O’Leary, Heather A⋅Mantel, Charlie⋅Mantel, Charlie R⋅Mantel, Charlie⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Messina-Graham, Steven⋅Messina-graham, Steven⋅Messina-Graham, Steven⋅Messina-graham, Steven⋅Hangoc, Giao⋅Hangoc, Giao⋅Hangoc, Giao⋅Farag, Sherif S⋅Farag, Sherif⋅Farag, Sherif⋅Rohrabaugh, Sara L⋅Rohrabaugh, Sara L⋅Rohrabaugh, Sara L⋅Ou, Xuan⋅Ou, Xuan⋅Ou, Xuan⋅Speth, Jennifer⋅Speth, Jennifer⋅Speth, Jennifer⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Campbell, Timothy B⋅Campbell, Timothy B and Campbell, Timothy B
Nature Medicine, vol. 18, pp. 1786–1796. | Journal Article
2010
Neurotrophins regulate bone marrow stromal cell IL-6 expression through the MAPK pathway.
Rezaee, Fariba⋅Rellick, Stephanie L⋅Piedimonte, Giovanni⋅Akers, Stephen M⋅O'Leary, Heather A⋅Martin, Karen H⋅Craig, Michael and Gibson, Laura F
PloS one. | Journal Article
 
VE-cadherin and PECAM-1 enhance ALL migration across brain microvascular endothelial cell monolayers.
Akers, Stephen M⋅O'Leary, Heather A⋅Minnear, Fred L⋅Craig, Michael⋅Vos, Jeffrey⋅Coad, James E and Gibson, Laura F
Experimental hematology. | Journal Article
 
VE-cadherin Regulates Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Sensitivity to Apoptosis.
O'Leary, Heather⋅Akers, Stephen M⋅Piktel, Debra⋅Walton, Cheryl⋅Fortney, James E⋅Martin, Karen H⋅Craig, Michael⋅Coad, James E and Gibson, Laura F
Cancer microenvironment : official journal of the International Cancer Microenvironment Society. | Journal Article
2009
Modulation of Philadelphia Chromosome-Positive Hematological Malignancies by the Bone Marrow Microenvironment
Wang, Lin⋅O’Leary, Heather and Gibson, Laura F.
(pp. 427–452). Springer New York
 
Neurotrophins Regulate Bone Marrow Stromal Cell IL-6 Expression through the MAPK Pathway.
Rezaee, F⋅Rellick, SL⋅Akers, SM⋅O’Leary, HA⋅Piedimonte, G and Gibson, LF
American Thoracic Society. | Conference Proceeding
2007
Ph+/VE-cadherin+ identifies a stem cell like population of acute lymphoblastic leukemia sustained by bone marrow niche cells.
Wang, Lin⋅O'Leary, Heather⋅Fortney, James and Gibson, Laura F
Blood. | Journal Article