151 Publications (Page 3 of 7)
2009
Alternative splicing of Na(V)1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T.
Jarecki, Brian W⋅Sheets, Patrick L⋅Xiao, Yucheng⋅Jackson, James O and Cummins, Theodore R
Channels (Austin, Tex.), vol. 3, (no. 4), pp. 259-67, 2009 Jul-Aug. | Journal Article
 
Alternative splicing of NaV1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T
Jarecki, Brian W⋅Sheets, Patrick L⋅Xiao, Yucheng⋅Jackson, James O and Cummins, Theodore R
Channels, vol. 3, (no. 4), pp. 269, 7/31/2009. | Journal Article
 
An Atypical Role for Collapsin Response Mediator Protein 2 (CRMP-2) in Neurotransmitter Release via Interaction with Presynaptic Voltage-gated Calcium Channels
Brittain, Joel M⋅Piekarz, Andrew D⋅Wang, Yuying⋅Kondo, Takako⋅Cummins, Theodore R and Khanna, Rajesh
Journal of Biological Chemistry, vol. 284, (no. 45), pp. 31375-31390, 2009. | Journal Article
 
Impact Of NaV1.7-PEPD Missense Mutations That Slow The Rate Of Inactivation On Sensory Neuronal Resurgent Sodium Currents
Jarecki, Brian W⋅Piekarz, Andrew D⋅Jackson, James O and Cummins, Theodore R
Biophysical Journal, vol. 96, (no. 3), pp. 663a, February 2009. | Journal Article
 
Transfection of rat or mouse neurons by biolistics or electroporation
Dib Hajj, Sulayman⋅Choi, Jin S⋅Macala, Lawrence J⋅Tyrrell, Lynda⋅Black, Joel A⋅Cummins, Theodore R and Waxman, Stephen G
Nature Protocols, vol. 4, (no. 8), pp. 1118-1126, 2009. | Journal Article
 
Voltage-clamp and current-clamp recordings from mammalian DRG neurons
Cummins, Theodore R⋅Rush, Anthony M⋅Estacion, Mark⋅Dib Hajj, Sulayman and Waxman, Stephen G
Nature Protocols, vol. 4, (no. 8), pp. 1103-1112, 2009. | Journal Article
 
Voltage-gated sodium channels in pain states: Role in pathophysiology and targets for treatment
Dib Hajj, Sulayman⋅Binshtok, AM⋅Cummins, Theodore R⋅Jarvis, MF⋅Samad, T. and Zimmermann, K.
Brain Research Reviews, vol. 60, (no. 1), pp. 65-83, 2009. | Journal Article
2008
Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine.
Sheets, Patrick L⋅Sheets, Patrick⋅Heers, Cara⋅Heers, Cara⋅Stoehr, Thomas⋅Stoehr, Thomas⋅Cummins, Theodore and Cummins, Theodore R
The Journal of pharmacology and experimental therapeutics, vol. 326, (no. 1), pp. 89-99, 2008/Jul. | Journal Article
 
Paroxysmal extreme pain disorder M1627K mutation in human Na[subscript v]1.7 renders DRG neurons hyperexcitable
Dib-Hajj, Sulayman⋅Estacion, Mark⋅Jarecki, Brian⋅Tyrrell, Lynda⋅Fischer, Tanya⋅Lawden, Mark⋅Cummins, Theodore and Waxman, Stephen
2008-09-19. | Journal Article
 
Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable.
Dib Hajj, Sulayman⋅Estacion, Mark⋅Jarecki, Brian W⋅Tyrrell, Lynda⋅Fischer, Tanya⋅Lawden, Mark⋅Cummins, Theodore R and Waxman, Stephen G
Molecular pain, vol. 4, pp. 37, 2008. | Journal Article
 
Paroxysmal extreme pain disorder mutations within the D3/S4-S5 linker of Nav1.7 cause moderate destabilization of fast inactivation.
Jarecki, Brian W⋅Sheets, Patrick L⋅Jackson, James O and Cummins, Theodore R
The Journal of physiology, vol. 586, (no. Pt 17), pp. 4137-53, 2008/Sep/1. | Journal Article
 
Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain ii voltage sensor in the closed configuration.
Xiao, Yucheng⋅Bingham, Jon Paul⋅Zhu, Weiguo⋅Moczydlowski, Edward⋅Liang, Songping and Cummins, Theodore R
The Journal of biological chemistry, vol. 283, (no. 40), pp. 27300-13, 2008/Oct/3. | Journal Article
 
Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells
Kondo, Takako⋅Sheets, Patrick L⋅Zopf, David A⋅Aloor, Heather L⋅Cummins, Theodore R⋅Chan, Rebecca J and Hashino, Eri
Proceedings of the National Academy of Sciences of the United States of America, vol. 105, (no. 15), Apr 15, 2008. | Journal Article
2007
A Na sub(v)1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity
Sheets, Patrick L⋅Jackson, James O⋅Waxman, Stephen G⋅Dib-Hajj, Sulayman D and Cummins, Theodore R
Journal of Physiology (London), vol. 581, (no. 3), pp. 1019-1031, 2007. | Journal Article
 
A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity.
Sheets, Patrick L⋅Jackson, James O⋅Waxman, Stephen G⋅Dib-Hajj, Sulayman D and Cummins, Theodore R
The Journal of physiology, vol. 581, (no. Pt 3), pp. 1019-31, 2007/Jun/15. | Journal Article
 
From genes to pain: [Na.sub.v]1.7 and human pain disorders
Dib-Hajj, Sulayman⋅Waxman, Stephen⋅Black, Joel and Cummins, Theodore
Trends in Neurosciences, vol. 30, (no. 11), pp. 555, 20071101. | Journal Article
 
From genes to pain: Na^sub v^1.7 and human pain disorders
Dib Hajj, Sulayman⋅Cummins, Theodore R⋅Black, Joel A and Waxman, Stephen G
Trends in Neurosciences, vol. 30, (no. 11), Nov 2007. | Journal Article
 
From genes to pain: Na v 1.7 and human pain disorders.
Dib Hajj, Sulayman⋅Cummins, Theodore R⋅Black, Joel A and Waxman, Stephen G
Trends in neurosciences, vol. 30, (no. 11), pp. 555-63, 2007/Nov. | Journal Article
 
Molecular Interactions of the Gating Modifier Toxin ProTx-II with Na@@dv@1.5: IMPLIED EXISTENCE OF A NOVEL TOXIN BINDING SITE COUPLED TO ACTIVATION
Smith, Jaime J⋅Cummins, Theodore R⋅Alphy, Sujith and Blumenthal, Kenneth M
Journal of Biological Chemistry, vol. 282, (no. 17), pp. 12687-12697, 2007. | Journal Article
 
Molecular Interactions of the Gating Modifier Toxin ProTx-II with Nav1.5
Smith, Jaime J⋅Cummins, Theodore R⋅Alphy, Sujith and Blumenthal, Kenneth M
Journal of Biological Chemistry, vol. 282, (no. 17), pp. 12697, 2007-04-27. | Journal Article
 
Molecular interactions of the gating modifier toxin ProTx-II with NaV 1.5: implied existence of a novel toxin binding site coupled to activation.
Smith, Jaime J⋅Cummins, Theodore R⋅Alphy, Sujith and Blumenthal, Kenneth M
The Journal of biological chemistry, vol. 282, (no. 17), pp. 12687-97, 2007/Apr/27. | Journal Article
 
Molecular Interactions of the Gating Modifier Toxin ProTx-II with Nav1.5: IMPLIED EXISTENCE OF A NOVEL TOXIN BINDING SITE COUPLED TO ACTIVATION
Smith, Jaime J⋅Cummins, Theodore R⋅Alphy, Sujith and Blumenthal, Kenneth M
Journal of biological chemistry., vol. 282, (no. 17), pp. 12687-12697, 2007. | Journal Article
 
Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons
Rush, Anthony M⋅Cummins, Theodore R and Waxman, Stephen G
Journal of Physiology (London), vol. 579, (no. 1), pp. 1-14, 2007. | Journal Article
 
Painful Research: Identification of a Small-Molecule Inhibitor that Selectively Targets Nav1.8 Sodium Channels
Rush, Anthony and Cummins, Theodore
Molecular Interventions, vol. 7, (no. 4), pp. 195, 20070801. | Journal Article
 
Setting up for the block: the mechanism underlying lidocaine's use-dependent inhibition of sodium channels.
Cummins, Theodore R
The Journal of physiology, vol. 582, (no. Pt 1), pp. 11, 2007/Jul/1. | Journal Article