90 Publications (Page 3 of 4)
2012
Cigarette Smoke-Induced CXCR3 Receptor Up-Regulation Mediates Endothelial Apoptosis
Green, Linden A⋅Petrusca, Daniela⋅Rajashekhar, Gangaraju⋅Gianaris, Tom⋅Schweitzer, Kelly S⋅Wang, Liang⋅Justice, Matthew J⋅Petrache, Irina and Clauss, Matthias A
American Journal of Respiratory Cell and Molecular Biology, vol. 47, (no. 6), pp. 807-14, Dec 2012. | Journal Article
 
Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases.
Lockett, Angelia D⋅Lockett, A.D.⋅Van Demark, M.⋅Van Demark, Mary⋅Gu, Y.⋅Gu, Yuan⋅Schweitzer, K.S.⋅Schweitzer, Kelly S⋅Sigua, Ninotchka⋅Sigua, N.⋅Kamocki, Krzysztof⋅Kamocki, K.⋅Fijalkowska, I.⋅Fijalkowska, Iwona⋅Garrison, J.⋅Garrison, Jana⋅Fisher, Amanda J⋅Fisher, A.J.⋅Serban, Karina⋅Serban, K.⋅Wise, R.A.⋅Wise, Robert A⋅Flotte, Terence R⋅Flotte, T.R.⋅Mueller, Christian⋅Mueller, C.⋅Presson Jr., R.G.⋅Presson, Robert G⋅Petrache, H.I.⋅Petrache, Horia I⋅Tuder, Rubin M⋅Tuder, R.M.⋅Petrache, Irina and Petrache, I.
Molecular medicine (Cambridge, Mass.), vol. 18, (no. 1), pp. 445-54, 2012. | Journal Article
 
LC3 as a potential therapeutic target in hypoxia-induced pulmonary hypertension.
Lahm, Tim and Petrache, Irina
Autophagy, vol. 8, (no. 7), pp. 1146-7, 2012/Jul/1. | Journal Article
 
Pathogenesis of chronic obstructive pulmonary disease
Tuder, Rubin M and Petrache, Irina
Journal of Clinical Investigation, vol. 122, (no. 8), pp. 2749-55, Aug 2012. | Journal Article
 
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
Yoshida, Toshinori⋅Mett, Igor⋅Bhunia, Anil K⋅Bowman, Joel⋅Perez, Mario⋅Zhang, Li⋅Gandjeva, Aneta⋅Zhen, Lijie⋅Chukwueke, Ugonma⋅Mao, Tianzhi⋅Richter, Amy⋅Brown, Emile⋅Ashush, Hagit⋅Notkin, Natalie⋅Gelfand, Anna⋅Thimmulappa, Rajesh K⋅Rangasamy, Tirumalai⋅Sussan, Thomas⋅Cosgrove, Gregory⋅Mouded, Majd⋅Shapiro, Steven D⋅Petrache, Irina⋅Biswal, Shyam S⋅Feinstein, Elena and Tuder, Rubin M
Nature, vol. 489, (no. 7417), pp. 767-773A, Sep 27, 2012. | Journal Article
2011
Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking.
Schweitzer, Kelly S⋅SCHWEITZER, Kelly S⋅Schweitzer, Kelly S⋅Schweitzer, Kelly S⋅Johnstone, Brian⋅Johnstone, Brian H⋅JOHNSTONE, Brian H⋅Johnstone, Brian H⋅Garrison, Jana⋅Garrison, Jana⋅Garrison, Jana⋅KAMOCKI, Krzysztof⋅Rush, Natalia I⋅Rush, Natalia I⋅Rush, Natalia I⋅BROWN, Mary Beth⋅Cooper, Scott⋅PRESSON, Robert G⋅Cooper, Scott⋅Cooper, Scott⋅Traktuev, Dmitry O⋅Traktuev, Dmitry O⋅BROXMEYER, Hal E⋅Traktuev, Dmitry O⋅Feng, Dongni⋅Feng, Dongni⋅Feng, Dongni⋅MARCH, Keith L⋅PETRACHE, Irina⋅Adamowicz, Jeremy J⋅Adamowicz, Jeremy J⋅Adamowicz, Jeremy J⋅Van Demark, Mary⋅Van Demark, Mary⋅Van Demark, Mary⋅GARRISON, Jana⋅Fisher, Amanda J⋅Fisher, Amanda J⋅RUSH, Natalia I⋅Fisher, Amanda J⋅Kamocki, Krzysztof⋅Kamocki, Krzysztof⋅COOPER, Scott⋅Kamocki, Krzysztof⋅Brown, Mary Beth⋅Brown, Mary B⋅Brown, Mary Beth⋅TRAKTUEV, Dmitry O⋅Presson, Robert G⋅FENG, DONGNI⋅Presson, Jr, Robert G⋅Presson, Jr, Robert G⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅ADAMOWICZ, Jeremy J⋅VAN DEMARK, Mary⋅March, Keith L⋅March, Keith L⋅March, Keith L⋅Petrache, Irina⋅Petrache, Irina⋅Petrache, Irina and FISHER, Amanda J
American journal of respiratory and critical care medicine, vol. 183, (no. 2), pp. 215-25, 2011/Jan/15. | Journal Article
 
Dihydroceramide-based response to hypoxia.
Devlin, Cecilia M⋅Lahm, Tim⋅Hubbard, Walter C⋅Van Demark, Mary⋅Wang, Kevin C⋅Wu, Xue⋅Bielawska, Alicja⋅Obeid, Lina M⋅Ivan, Mircea and Petrache, Irina
The Journal of biological chemistry, vol. 286, (no. 44), pp. 38069-78, 2011/Nov/4. | Journal Article
 
Involvement of ceramide in cell death responses in the pulmonary circulation.
Petrache, Irina⋅Petrache, Irina⋅Petrusca, Daniela N⋅Petrusca, Daniela N⋅Bowler, Russell⋅Bowler, Russell P⋅Kamocki, Krzysztof and Kamocki, Krzysztof
Proceedings of the American Thoracic Society, vol. 8, (no. 6), pp. 492-6, 2011/Nov. | Journal Article
 
Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice.
Clauss, Matthias A⋅Voswinckel, Robert⋅Rajashekhar, Gangaraju⋅Sigua, Ninotchka L⋅Fehrenbach, Heinz⋅Rush, Natalia I⋅Schweitzer, Kelly S⋅Yildirim, Ali Ö⋅Kamocki, Krzysztof⋅Fisher, Amanda J⋅Gu, Yuan⋅Safadi, Bilal⋅Nikam, Sandeep⋅Hubbard, Walter C⋅Tuder, Rubin M⋅Twigg, Homer L⋅Presson, Robert G⋅Sethi, Sanjay and Petrache, Irina
The Journal of clinical investigation, vol. 121, (no. 6), pp. 2470-9, 2011/Jun. | Journal Article
 
Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides.
Schweitzer, Kelly S⋅Schweitzer, Kelly S⋅Hatoum, Hadi⋅Hatoum, Hadi⋅Brown, Mary Beth⋅Brown, Mary B⋅Gupta, Mehak⋅Gupta, Mehak⋅Justice, Matthew J⋅Justice, Matthew J⋅Beteck, Besem⋅Beteck, Besem⋅Van Demark, Mary⋅Van Demark, Mary⋅Gu, Yuan⋅Gu, Yuan⋅Presson, Robert G⋅Presson, Jr, Robert G⋅Hubbard, Walter C⋅Hubbard, Walter C⋅Petrache, Irina and Petrache, Irina
American journal of physiology. Lung cellular and molecular physiology, vol. 301, (no. 6), pp. L836-46, 2011/Dec. | Journal Article
 
Periostin Regulates Goblet Cell Metaplasia in a Model of Allergic Airway Inflammation
Sehra, Sarita⋅Sehra, Sarita⋅Yao, Weiguo⋅Yao, Weiguo⋅Nguyen, Evelyn T⋅Nguyen, Evelyn T⋅Ahyi, Ayele-Nati N⋅Ahyi, Ayele-Nati N⋅Tuana, Florencia M Barbé⋅Barbe Tuana, Florencia M⋅Ahlfeld, Shawn K⋅Ahlfeld, Shawn K⋅Snider, Paige⋅Snider, Paige⋅Tepper, Robert S⋅Tepper, Robert S⋅Petrache, Irina⋅Petrache, Irina⋅Conway, Simon J⋅Conway, Simon⋅Kaplan, Mark H and Kaplan, Mark H
Journal of Immunology, vol. 186, (no. 8), pp. 4959-4966, 2011. | Journal Article
 
Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact.
Presson Jr., R.G.⋅Presson, Robert G⋅Brown, Mary B⋅Fisher, Amanda J⋅Sandoval, Ruben M⋅Dunn, Kenneth W⋅Lorenz, Kevin S⋅Delp, Edward J⋅Salama, Paul⋅Molitoris, Bruce A and Petrache, Irina
The American journal of pathology, vol. 179, (no. 1), pp. 75-82, 2011/Jul. | Journal Article
2010
Lung disease associated with alpha1-antitrypsin deficiency.
Tuder, Rubin M⋅Janciauskiene, Sabina M and Petrache, Irina
Proceedings of the American Thoracic Society, vol. 7, (no. 6), pp. 381-6, 2010/Nov. | Journal Article
 
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema.
Yoshida, Toshinori⋅Mett, Igor⋅Bhunia, Anil K⋅Bowman, Joel⋅Perez, Mario⋅Zhang, Li⋅Gandjeva, Aneta⋅Zhen, Lijie⋅Chukwueke, Ugonma⋅Mao, Tianzhi⋅Richter, Amy⋅Brown, Emile⋅Ashush, Hagit⋅Notkin, Natalie⋅Gelfand, Anna⋅Thimmulappa, Rajesh K⋅Rangasamy, Tirumalai⋅Sussan, Thomas⋅Cosgrove, Gregory⋅Mouded, Majd⋅Shapiro, Steven D⋅Petrache, Irina⋅Biswal, Shyam S⋅Feinstein, Elena and Tuder, Rubin M
Nature medicine, vol. 16, (no. 7), pp. 767-73, 2010/Jul. | Journal Article
 
Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages.
Petrusca, Daniela N⋅Petrusca, Daniela N⋅Gu, Yuan⋅Gu, Yuan⋅Adamowicz, Jeremy J⋅Adamowicz, Jeremy J⋅Rush, Natalia I⋅Rush, Natalia I⋅Hubbard, Walter C⋅Hubbard, Walter C⋅Smith, Patricia A⋅Smith, Patricia A⋅Berdyshev, Evgeni V⋅Berdyshev, Evgeni V⋅Birukov, Konstantin⋅Birukov, Konstantin G⋅Lee, Chao-Hung⋅Lee, Chao-Hung⋅Tuder, Rubin M⋅Tuder, Rubin M⋅Twigg, Homer L⋅Twigg, 3rd, Homer L⋅Vandivier, R. W⋅Vandivier, R William⋅Petrache, Irina and Petrache, Irina
The Journal of biological chemistry, vol. 285, (no. 51), pp. 40322-32, 2010/Dec/17. | Journal Article
 
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema.
Diab, Khalil J⋅Adamowicz, Jeremy J⋅Kamocki, Krzysztof⋅Rush, Natalia I⋅Garrison, Jana⋅Gu, Yuan⋅Schweitzer, Kelly S⋅Skobeleva, Anastasia⋅Rajashekhar, Gangaraju⋅Hubbard, Walter C⋅Berdyshev, Evgeny and Petrache, Irina
American journal of respiratory and critical care medicine, vol. 181, (no. 4), pp. 344-52, 2010/Feb/15. | Journal Article
2009
A monoclonal rat anti-mouse EMAP II antibody that functionally neutralizes pro- and mature-EMAP II in vitro.
Rajashekhar, Gangaraju⋅Mitnacht-Kraus, Rita⋅Ispe, Ute⋅Garrison, Jana⋅Hou, Yonghao⋅Taylor, Brian⋅Petrache, Irina⋅Vestweber, Dietmar and Clauss, Matthias A
Journal of immunological methods, vol. 350, (no. 1-2), pp. 22-8, 2009/Oct/31. | Journal Article
 
CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis.
Noe, Julie⋅Petrusca, Daniela⋅Rush, Natalia⋅Deng, Ping⋅VanDemark, Mary⋅Berdyshev, Evgeny⋅Gu, Yuan⋅Smith, Patricia⋅Schweitzer, Kelly S⋅Pilewsky, Joseph⋅Natarajan, Viswanathan⋅Xu, Zao C⋅Obukhov, Alexander G and Petrache, Irina
American journal of respiratory cell and molecular biology, vol. 41, (no. 3), pp. 314-23, 2009/Sep. | Journal Article
 
Mechanism of alpha-1 antitrypsin endocytosis by lung endothelium.
Sohrab, Sadaf⋅Sohrab, Sadaf⋅Petrusca, Daniela N⋅Petrusca, Daniela N⋅Lockett, Angelia D⋅Lockett, Angelia D⋅Schweitzer, Kelly S⋅Schweitzer, Kelly S⋅Rush, Natalia I⋅Rush, Natalia I⋅Gu, Yuan⋅Gu, Yuan⋅Kamocki, Krzysztof⋅Kamocki, Krzysztof⋅Garrison, Jana⋅Garrison, Jana⋅Petrache, Irina and Petrache, Irina
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol. 23, (no. 9), pp. 3149-58, 2009/Sep. | Journal Article
 
Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency.
Petrache, Irina⋅Hajjar, Joud and Campos, Michael
Biologics : targets & therapy, vol. 3, pp. 193-204, 2009. | Journal Article
 
Type V collagen-induced oral tolerance plus low-dose cyclosporine prevents rejection of MHC class I and II incompatible lung allografts.
Yamada, Yoshito⋅Sekine, Yasuo⋅Yoshida, Shigetoshi⋅Yasufuku, Kazuhiro⋅Petrache, Irina⋅Benson, Heather L⋅Brand, David⋅Yoshino, Ichiro and Wilkes, David S
Journal of immunology (Baltimore, Md. : 1950), vol. 183, (no. 1), pp. 237-45, 2009/Jul/1. | Journal Article
2008
Anti-type V collagen humoral immunity in lung transplant primary graft dysfunction.
Iwata, Takekazu⋅Philipovskiy, Alexander⋅Fisher, Amanda J⋅Presson, Robert G⋅Chiyo, Masako⋅Lee, Jae⋅Mickler, Elizabeth⋅Smith, Gerald N⋅Petrache, Irina⋅Brand, David B⋅Burlingham, William J⋅Gopalakrishnan, Bagavathi⋅Greenspan, Daniel S⋅Christie, Jason D and Wilkes, David S
Journal of immunology (Baltimore, Md. : 1950), vol. 181, (no. 8), pp. 5738-47, 2008/Oct/15. | Journal Article
 
Apoptotic sphingolipid signaling by ceramides in lung endothelial cells.
Medler, Terry⋅Medler, Terry R⋅Petrusca, Daniela N⋅Petrusca, Daniela⋅Lee, Patty⋅Lee, Patty J⋅Hubbard, Walter C⋅Hubbard, Walter⋅Berdyshev, Evgeny⋅Berdyshev, Evgeny⋅Skirball, Jarrett⋅Skirball, Jarrett⋅Kamocki, Krzysztof⋅Kamocki, Krzysztof⋅Schuchman, Edward⋅Schuchman, Edward⋅Tuder, Rubin⋅Tuder, Rubin M⋅Petrache, Irina and Petrache, Irina
American journal of respiratory cell and molecular biology, vol. 38, (no. 6), pp. 639-46, 2008/Jun. | Journal Article
 
HIV associated pulmonary emphysema: a review of the literature and inquiry into its mechanism
Petrache, Irina⋅Diab, K.⋅Knox, Ken S⋅Twigg, Homer L⋅Stephens, R. S⋅Flores, Sonia and Tuder, Rubin M
Thorax, vol. 63, (no. 5), pp. 463-469, 2008. | Journal Article
 
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide
Petrache, Irina⋅Medler, Terry R⋅Richter, Amy T⋅Kamocki, Krzysztof⋅Chukwueke, Ugonma⋅Zhen, Lijie⋅Gu, Yuan⋅Adamowicz, Jeremy⋅Schweitzer, Kelly S⋅Hubbard, Walter C⋅Berdyshev, Evgeny V⋅Lungarella, Giuseppe and Tuder, Rubin M
American Journal of Physiology, vol. 295, (no. 1), Jul 2008. | Journal Article