37 Publications (Page 1 of 2)
2020
Alveolar Bone Protection by Targeting the SH3BP2‐SYK Axis in Osteoclasts
Kittaka, MizuhoYoshimoto, TetsuyaSchlosser, CollinRottapel, RobertKajiya, MikihitoKurihara, HidemiReichenberger, Ernst J and Ueki, Yasuyoshi
Journal of Bone and Mineral Research, vol. 35, (no. 2), pp. 395, February 2020. | Journal Article
 
Investigating global gene expression changes in a murine model of cherubism
Sharma, TulikaSharma, TulikaSharma, TulikaSharma, TulikaCotney, JustinCotney, JustinCotney, JustinCotney, JustinSingh, VijenderSingh, VijenderSingh, VijenderSingh, VijenderSanjay, ArchanaSanjay, ArchanaSanjay, ArchanaSanjay, ArchanaReichenberger, Ernst JReichenberger, Ernst JReichenberger, Ernst JReichenberger, Ernst JUeki, YasuyoshiUeki, YasuyoshiUeki, YasuyoshiUeki, YasuyoshiMaye, PeterMaye, PeterMaye, Peter and Maye, Peter
Bone, vol. 135, pp. 115315, June 2020. | Journal Article
 
Microbe-Dependent Exacerbated Alveolar Bone Destruction in Heterozygous Cherubism Mice
Kittaka, MizuhoYoshimoto, TetsuyaSchlosser, CollinKajiya, MikihitoKurihara, HidemiReichenberger, Ernst J and Ueki, Yasuyoshi
JBMR Plus, pp. e10352, 2020-04-14. | Journal Article
 
Optineurin regulates osteoblastogenesis through STAT1
Mizuno, NoriyoshiIwata, TomoyukiOhsawa, RyosukeOuhara, KazuhisaMatsuda, ShinjiKajiya, MikihitoMatsuda, YukikoKume, KodaiTada, YuiMorino, HiroyukiYoshimoto, TetsuyaUeki, YasuyoshiMihara, KeichiroSotomaru, YusukeTakeda, KatsuhiroMunenaga, SyuichiFujita, TsuyoshiKawaguchi, HiroyukiShiba, HidekiKawakami, Hideshi and Kurihara, Hidemi
Biochemical and Biophysical Research Communications, vol. 525, (no. 4), pp. 894, 2020-05-14. | Journal Article
 
RANKL-independent osteoclastogenesis in the SH3BP2 cherubism mice.
Kittaka, MizuhoYoshimoto, TetsuyaHoffman, HenryLevitan, Marcus Evan and Ueki, Yasuyoshi
Bone reports, vol. 12, pp. 100258, June 2020. | Journal Article
2019
Epigenetic regulation of NfatC1 transcription and osteoclastogenesis by nicotinamide phosphoribosyl transferase in the pathogenesis of arthritis
Li, XuananIslam, ShamimaXiong, MinNsumu, Ndona NLee, Jr, Mark WZhang, Li QinUeki, YasuyoshiHeruth, Daniel PLei, Guanghua and Ye, Shui Qing
Cell death discovery, vol. 5, (no. 1), pp. 62, 2019-00-00. | Journal Article
 
Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL- Fas lpr Mice
Nagasu, AkikoMukai, TomoyukiIseki, MasanoriKawahara, KyokoTsuji, ShokoNagasu, HajimeUeki, YasuyoshiIshihara, KatsuhikoKashihara, Naoki and Morita, Yoshitaka
Cells, vol. 8, (no. 5), 2019-04-30. | Journal Article
 
Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Faslpr Mice
Nagasu, AkikoMukai, TomoyukiIseki, MasanoriKawahara, KyokoTsuji, ShokoNagasu, HajimeUeki, YasuyoshiIshihara, KatsuhikoKashihara, Naoki and Morita, Yoshitaka
Cells, vol. 8, (no. 5), pp. 402, 2019-04-30. | Journal Article
2018
Cherubism Mice Also Deficient in c‐Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts
Kittaka, MizuhoMayahara, KotoeMukai, TomoyukiYoshimoto, TetsuyaYoshitaka, TeruhitoGorski, Jeffrey P and Ueki, Yasuyoshi
Journal of Bone and Mineral Research, vol. 33, (no. 1), pp. 181, January 2018. | Journal Article
 
Mouse Cre Models for the Study of Bone Diseases
Dallas, SarahXie, YixiaShiflett, Lora and Ueki, Yasuyoshi
Current Osteoporosis Reports, vol. 16, (no. 4), pp. 477, 20180800. | Journal Article
 
Pharmacological inhibition of tankyrase induces bone loss in mice by increasing osteoclastogenesis
Fujita, ShunichiMukai, TomoyukiMito, TakafumiKodama, ShokoNagasu, AkikoKittaka, MizuhoSone, TerukiUeki, Yasuyoshi and Morita, Yoshitaka
Bone, vol. 106, pp. 166, January 2018. | Journal Article
 
Rescue of a cherubism bone marrow stromal culture phenotype by reducing TGF[beta] signaling
Liu, YalingSharma, TulikaChen, I-PingReichenberger, ErnstUeki, YasuyoshiArif, YumnaParisi, Daniel and Maye, Peter
Bone, vol. 111, pp. 28, 20180601. | Journal Article
 
Second‐Generation SYK Inhibitor Entospletinib Ameliorates Fully Established Inflammation and Bone Destruction in the Cherubism Mouse Model
Yoshimoto, TetsuyaHayashi, TatsuhideKondo, ToshioKittaka, MizuhoReichenberger, Ernst J and Ueki, Yasuyoshi
Journal of Bone and Mineral Research, vol. 33, (no. 8), pp. 1519, August 2018. | Journal Article
2016
Molecular and Cellular Pathogenesis of Cherubism
Ueki, Yasuyoshi and Ueki, Yasuyoshi
Clinical calcium, vol. 26, (no. 6), pp. 918, 2016-Jun. | Journal Article
2015
Loss of SH3 Domain–Binding Protein 2 Function Suppresses Bone Destruction in Tumor Necrosis Factor–Driven and Collagen‐Induced Arthritis in Mice
Mukai, TomoyukiMukai, TomoyukiGallant, RichardGallant, RichardIshida, ShuIshida, ShuKittaka, MizuhoKittaka, MizuhoYoshitaka, TeruhitoYoshitaka, TeruhitoFox, David AFox, David AMorita, YoshitakaMorita, YoshitakaNishida, KeiichiroNishida, KeiichiroRottapel, RobertRottapel, RobertUeki, Yasuyoshi and Ueki, Yasuyoshi
Arthritis & Rheumatology, vol. 67, (no. 3), pp. 667, March 2015. | Journal Article
2014
Enhanced TLR-MYD88 Signaling Stimulates Autoinflammation in SH3BP2 Cherubism Mice and Defines the Etiology of Cherubism
Yoshitaka, TeruhitoYoshitaka, TeruhitoMukai, TomoyukiMukai, TomoyukiKittaka, MizuhoKittaka, MizuhoAlford, Lisa MAlford, Lisa MMasrani, SalomeMasrani, SalomeIshida, ShuIshida, ShuYamaguchi, KenYamaguchi, KenYamada, MotohikoYamada, MotohikoMizuno, NoriyoshiMizuno, NoriyoshiOlsen, Bjorn ROlsen, Bjorn RReichenberger, Ernst JReichenberger, Ernst JUeki, Yasuyoshi and Ueki, Yasuyoshi
Cell Reports, vol. 8, (no. 6), pp. 1766, 2014-09-25. | Journal Article
 
Etanercept Administration to Neonatal SH3BP2 Knock-In Cherubism Mice Prevents TNF-[alpha]-Induced Inflammation and Bone Loss
Yoshitaka, TeruhitoYoshitaka, TeruhitoIshida, ShuIshida, ShuMukai, TomoyukiMukai, TomoyukiKittaka, MizuhoKittaka, MizuhoReichenberger, ErnstReichenberger, Ernst JUeki, Yasuyoshi and Ueki, Yasuyoshi
Journal of Bone and Mineral Research, vol. 29, (no. 5), pp. 1170, 20140501. | Journal Article
 
SH3BP2 Cherubism Mutation Potentiates TNF-[alpha]-Induced Osteoclastogenesis via NFATc1 and TNF-[alpha]-Mediated Inflammatory Bone Loss
Mukai, TomoyukiMukai, TomoyukiIshida, ShuIshida, ShuIshikawa, RemiIshikawa, RemiYoshitaka, TeruhitoYoshitaka, TeruhitoKittaka, MizuhoKittaka, MizuhoGallant, RichardGallant, RichardLin, Yi-LingLin, Yi-LingRottapel, RobertRottapel, RobertBrotto, MarcoBrotto, MarcoReichenberger, ErnstReichenberger, Ernst JUeki, Yasuyoshi and Ueki, Yasuyoshi
Journal of Bone and Mineral Research, vol. 29, (no. 12), pp. 2618, 20141201. | Journal Article
 
SH3BP2 Gain-Of-Function Mutation Exacerbates Inflammation and Bone Loss in a Murine Collagen-Induced Arthritis Model
Mukai, TomoyukiMukai, TomoyukiGallant, RichardGallant, RichardIshida, ShuIshida, ShuYoshitaka, TeruhitoYoshitaka, TeruhitoKittaka, MizuhoKittaka, MizuhoNishida, KeiichiroNishida, KeiichiroFox, David AFox, David AMorita, YoshitakaMorita, YoshitakaUeki, Yasuyoshi and Ueki, Yasuyoshi
PloS one, vol. 9, (no. 8), pp. e105518, 2014-00-00. | Journal Article
2013
Bone marrow transplantation improves autoinflammation and inflammatory bone loss in SH3BP2 knock-in cherubism mice
Yoshitaka, TeruhitoYoshitaka, TeruhitoKittaka, MizuhoKittaka, MizuhoIshida, ShuIshida, ShuMizuno, NoriyoshiMizuno, NoriyoshiMukai, TomoyukiMukai, TomoyukiUeki, Yasuyoshi and Ueki, Yasuyoshi
Bone, vol. 71, pp. 209, 2013. | Journal Article
2011
Clonal overgrowth of esophageal smooth muscle cells in diffuse leiomyomatosis-Alport syndrome caused by partial deletion in COL4A5 and COL4A6 genes
Oohashi, ToshitakaOohashi, ToshitakaNaito, IchiroNaito, IchiroUeki, YasuyoshiUeki, YasuyoshiYamatsuji, TomokiYamatsuji, TomokiPermpoon, RattiyaPermpoon, RattiyaTanaka, NoriakiTanaka, NoriakiNaomoto, YoshioNaomoto, YoshioNinomiya, Yoshifumi and Ninomiya, Yoshifumi
Matrix Biology, vol. 30, (no. 1), pp. 8, January 2011. | Journal Article
 
Loss of Tankyrase-Mediated Destruction of 3BP2 Is the Underlying Pathogenic Mechanism of Cherubism
Levaot, NoamLevaot, NoamVoytyuk, OleksandrVoytyuk, OleksandrDimitriou, IoannisDimitriou, IoannisSircoulomb, FabriceSircoulomb, FabriceChandrakumar, ArunChandrakumar, ArunDeckert, MarcelDeckert, MarcelKrzyzanowski, Paul MKrzyzanowski, Paul MScotter, AndrewScotter, AndrewGu, ShengqingGu, ShengqingJanmohamed, SalimaJanmohamed, SalimaCong, FengCong, FengSimoncic, Paul DSimoncic, Paul DUeki, YasuyoshiUeki, YasuyoshiLa Rose, JoseLa Rose, JoseRottapel, Robert and Rottapel, Robert
Cell, vol. 147, (no. 6), pp. 1339, 2011. | Journal Article
2010
Cherubism gene Sh3bp2 is important for optimal bone formation, osteoblast differentiation, and function
Mukherjee, Padma MMukherjee, PadmaWang, Chiachien JWang, ChiachienChen, I PingChen, I.-PingJafarov, ToghrulJafarov, ToghrulOlsen, Bjorn ROlsen, BjornUeki, YasuyoshiUeki, YasuyoshiReichenberger, Ernst J and Reichenberger, Ernst
American Journal of Orthodontics and Dentofacial Orthopedics, vol. 138, (no. 2), pp. 140.e11, 2010. | Journal Article
 
Pro416Arg cherubism mutation in Sh3bp2 knock-in mice affects osteoblasts and alters bone mineral and matrix properties
Wang, ChiachienWang, Chiachien JChen, I PingChen, I.-PingKoczon-Jaremko, BoguslawaKoczon-Jaremko, BoguslawaBoskey, AdeleBoskey, Adele LUeki, YasuyoshiUeki, YasuyoshiKuhn, LiisaKuhn, LiisaReichenberger, Ernst and Reichenberger, Ernst J
Bone, vol. 46, (no. 5), pp. 1315, 2010. | Journal Article
2009
SH3BP2 is a Critical Regulator of Macrophage and Osteoclast Response to M-CSF and RANKL Stimulation
McMahon, MarkMcMahon, MarkUeki, Yasuyoshi and Ueki, Yasuyoshi
HSS Journal, vol. 5, (no. 1), pp. 50, 20090200. | Journal Article