Despite the large focus on the role of estrogen, progesterone, and testosterone acting through their respective receptors, reproduction is also affected by other NRs; however, how NR signaling in other cell types and organs influence reproduction is poorly understood.
Previous studies have highlighted roles of NRs directly in the germline; however, it remains to be determined how the actions of NRs in peripheral tissues indirectly influence oogenesis.
Research areas:
- Developmental Mechanisms and Regulation in Eukaryotic Systems
- Eukaryotic Cell Biology, Cytoskeleton, and Signaling
Research:
- Nuclear receptors as a model
- Nuclear receptors as a model to understand oogenesis
- The Drosophila ovary as a model
Most studies have focused on how an individual nuclear receptor acts within a specific cell type or tissue itself to control transcripts that directly influence that tissue of interest.
Research Interests:
- physiological control of reproduction through inter-organ communication
