Dr. Tao Lu has an extensive background in signaling transduction, molecular and cellular biology, biochemistry, genetics, and pharmacology with specific expertise in NF-kB signaling, post-translational modification, cancer epigenetics, and drug discovery.
My research centers on the multi-functional transcription factor nuclear factor kB (NFkB). Since many cancers are characterized by constitutive activation of NFkB, my recent work has focused on investigating the causes of constitutive activation of NFkB in cancer and to develop and use novel forward genetic screening methods to identify regulators of NFkB. I expect this research to lead to new strategies for the prevention and treatment of cancer.
My research focuses on addressing how NF-κB is regulated and how this regulation contributes to tumorigenesis
Research:
- Epigenetic Regulation of NF-kB in cancer and inflammatory disease
- Using Validation-based insertional mutagenesis (VBIM) technique to discover novel genes
Research: Cellular and Molecular Metabolism