23 Publications
2021
Prostaglandin E2 Regulates Bipotent Monocyte-Dendritic Progenitor Cell Lineage-Commitment.
Singh, Pratibha and Pelus, Louis M
Stem cell reviews and reports, vol. 17, (no. 6), pp. 2338-2346, December 2021. | Journal Article
2020
Aging-Related Reduced Expression of CXCR4 on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects.
Singh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaKacena, Melissa AKacena, Melissa AKacena, Melissa AKacena, Melissa AOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MPelus, Louis MPelus, Louis MPelus, Louis M and Pelus, Louis M
Stem cell reviews and reports, vol. 16, (no. 4), pp. 684-692, August 2020. | Journal Article
 
A Single Radioprotective Dose of Prostaglandin E2 Blocks Irradiation-Induced Apoptotic Signaling and Early Cycling of Hematopoietic Stem Cells.
Patterson, Andrea MLiu, LiqiongSampson, Carol HPlett, P ArturLi, HonggeSingh, PratibhaMohammad, Khalid SHoggatt, JonathanCapitano, Maegan LOrschell, Christie M and Pelus, Louis M
Stem cell reports, vol. 15, (no. 2), pp. 358-373, August 11, 2020. | Journal Article
 
CXCR4 expression in the bone marrow microenvironment is required for hematopoietic stem and progenitor cell maintenance and early hematopoietic regeneration after myeloablation.
Singh, PratibhaSingh, PratibhaSingh, PratibhaMohammad, Khalid SMohammad, Khalid SMohammad, Khalid SPelus, Louis MPelus, Louis M and Pelus, Louis M
Stem cells (Dayton, Ohio), vol. 38, (no. 7), pp. 849-859, July 2020. | Journal Article
 
Optimizing and Profiling Prostaglandin E2 as a Medical Countermeasure for the Hematopoietic Acute Radiation Syndrome.
Patterson, Andrea MWu, TongChua, Hui LinSampson, Carol HFisher, AlexaSingh, PratibhaGuise, Theresa AFeng, HailinMuldoon, JessicaWright, LauraPlett, P ArturPelus, Louis M and Orschell, Christie M
Radiation research, December 10, 2020. | Journal Article
2019
Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass
Maupin, Kevin AMaupin, Kevin AMaupin, Kevin AMaupin, Kevin AMaupin, Kevin AHimes, Evan RHimes, Evan RHimes, Evan RHimes, Evan RHimes, Evan RPlett, Artur PPlett, Artur PPlett, Artur PPlett, Artur PPlett, Artur PChua, Hui LinChua, Hui LinChua, Hui LinChua, Hui LinChua, Hui LinSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaGhosh, JoydeepGhosh, JoydeepGhosh, JoydeepGhosh, JoydeepGhosh, JoydeepMohamad, Safa FMohamad, Safa FMohamad, Safa FMohamad, Safa FMohamad, Safa FAbeysekera, IrushiAbeysekera, IrushiAbeysekera, IrushiAbeysekera, IrushiAbeysekera, IrushiFisher, AlexaFisher, AlexaFisher, AlexaFisher, AlexaFisher, AlexaSampson, CarolSampson, CarolSampson, CarolSampson, CarolSampson, CarolHong, Jung-MinHong, Jung-MinHong, Jung-MinHong, Jung-MinHong, Jung-MinChildress, PaulChildress, PaulChildress, PaulChildress, PaulChildress, PaulAlvarez, MartaAlvarez, MartaAlvarez, MartaAlvarez, MartaAlvarez, MartaSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FBruzzaniti, AngelaBruzzaniti, AngelaBruzzaniti, AngelaBruzzaniti, AngelaBruzzaniti, AngelaPelus, Louis MPelus, Louis MPelus, Louis MPelus, Louis MPelus, Louis MOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MKacena, Melissa AKacena, Melissa AKacena, Melissa AKacena, Melissa A and Kacena, Melissa A
Bone, vol. 127, pp. 459, October 2019. | Journal Article
2018
Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell
Hoggatt, JonathanHoggatt, JonathanHoggatt, JonathanSingh, PratibhaSingh, PratibhaSingh, PratibhaTate, Tiffany ATate, Tiffany ATate, Tiffany AChou, Bin-KuanChou, Bin-KuanChou, Bin-KuanDatari, Shruti RDatari, Shruti RDatari, Shruti RFukuda, SeijiFukuda, SeijiFukuda, SeijiLiu, LiqiongLiu, LiqiongLiu, LiqiongKharchenko, Peter VKharchenko, Peter VKharchenko, Peter VSchajnovitz, AmirSchajnovitz, AmirSchajnovitz, AmirBaryawno, NinibBaryawno, NinibBaryawno, NinibMercier, Francois EMercier, Francois EMercier, Francois EBoyer, JosephBoyer, JosephBoyer, JosephGardner, JasonGardner, JasonGardner, JasonMorrow, Dwight MMorrow, Dwight MMorrow, Dwight MScadden, David TScadden, David TScadden, David TPelus, Louis MPelus, Louis M and Pelus, Louis M
Cell, vol. 172, (no. 1-2), pp. 204.e10, 2018-01-11. | Journal Article
 
Survivin Is Required for Mouse and Human Bone Marrow Mesenchymal Stromal Cell Function
Singh, PratibhaSingh, PratibhaFukuda, SeijiFukuda, SeijiLiu, LiqiongLiu, LiqiongChitteti, Brahmananda ReddyChitteti, Brahmananda ReddyPelus, Louis M and Pelus, Louis M
STEM CELLS, vol. 36, (no. 1), pp. 129, January 2018. | Journal Article
2017
IFN-1 Bid crosstalk: foe or friend to stem cells
Singh, Pratibha and Pelus, Louis M
Stem cell investigation, vol. 4, pp. 18, 2017-00-00. | Journal Article
 
Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells
Singh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaHoggatt, JonathanHoggatt, JonathanHoggatt, JonathanHoggatt, JonathanHoggatt, JonathanHoggatt, JonathanKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MKamocka, Malgorzata MMohammad, Khalid SMohammad, Khalid SMohammad, Khalid SMohammad, Khalid SMohammad, Khalid SMohammad, Khalid SSaunders, Mary RSaunders, Mary RSaunders, Mary RSaunders, Mary RSaunders, Mary RSaunders, Mary RLi, HonggeLi, HonggeLi, HonggeLi, HonggeLi, HonggeLi, HonggeSpeth, JenniferSpeth, JenniferSpeth, JenniferSpeth, JenniferSpeth, JenniferSpeth, JenniferCarlesso, NadiaCarlesso, NadiaCarlesso, NadiaCarlesso, NadiaCarlesso, NadiaCarlesso, NadiaGuise, Theresa AGuise, Theresa AGuise, Theresa AGuise, Theresa AGuise, Theresa AGuise, Theresa APelus, Louis MPelus, Louis MPelus, Louis MPelus, Louis MPelus, Louis M and Pelus, Louis M
The Journal of clinical investigation, vol. 127, (no. 12), pp. 4540, 2017-12-01. | Journal Article
2016
Internal Tandem Duplication in FLT3 Attenuates Proliferation and Regulates Resistance to the FLT3 Inhibitor AC220 by Modulating p21Cdkn1a and Pbx1 in Hematopoietic Cells
Abe, MarikoAbe, MarikoPelus, Louis MPelus, Louis MSingh, PratibhaSingh, PratibhaHirade, TomohiroHirade, TomohiroOnishi, ChieOnishi, ChiePurevsuren, JamiyanPurevsuren, JamiyanTaketani, TakeshiTaketani, TakeshiYamaguchi, SeijiYamaguchi, SeijiFukuda, Seiji and Fukuda, Seiji
PloS one, vol. 11, (no. 7), pp. e0158290, 2016-00-00. | Journal Article
 
Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell
Hoggatt, JonathanHoggatt, JonathanSingh, PratibhaSingh, PratibhaTate, TiffanyTate, TiffanyKharchenko, Peter VKharchenko, Peter VSchajnovitz, AmirSchajnovitz, AmirBarawnyo, NinibBarawnyo, NinibMercier, FrancoisMercier, FrancoisMorrow, DwightMorrow, DwightScadden, David TScadden, David TPelus, Louis M and Pelus, Louis M
Blood, vol. 128, (no. 22), pp. 368, 2016-12-02. | Journal Article
2014
Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment.
Speth, JenniferHoggatt, JonathanSingh, Pratibha and Pelus, Louis M
Blood, vol. 123, (no. 2), pp. 203-7, 2014/Jan/9. | Journal Article
 
Survivin Modulates Genes with Divergent Molecular Functions and Regulates Proliferation of Hematopoietic Stem Cells through Evi-1
Fukuda, SeijiFukuda, SeijiHoggatt, JonathanHoggatt, JonathanSingh, PratibhaSingh, PratibhaAbe, MarikoAbe, MarikoSpeth, JenniferSpeth, JenniferHu, PeirongHu, PeirongConway, EdwardConway, EdwardNucifora, GiuseppinaNucifora, GiuseppinaYamaguchi, SeijiYamaguchi, SeijiPelus, Louis and Pelus, Louis
2014. | Journal Article
2013
Differential stem- and progenitor-cell trafficking by prostaglandin E2.
Hoggatt, JonathanMohammad, Khalid SSingh, PratibhaHoggatt, Amber FChitteti, Brahmananda RSpeth, JenniferHu, PeirongPoteat, Bradley AStilger, Kayla NFerraro, FrancescaSilberstein, LevWong, Frankie KFarag, Sherif SCzader, MagdalenaMilne, Ginger LBreyer, Richard MSerezani, Carlos HScadden, DavidGuise, Theresa ASrour, Edward F and Pelus, Louis M
Nature, vol. 495, (no. 7441), pp. 365-9, 2013/Mar/21. | Journal Article
 
Differential Stem and Progenitor Cell Trafficking by Prostaglandin E2
Hoggatt, JonathanHoggatt, JonathanHoggatt, JonathanHoggatt, JonathanHoggatt, JonathanHoggatt, JonathanMohammad, KhalidMohammad, KhalidMohammad, KhalidMohammad, KhalidMohammad, KhalidMohammad, KhalidSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaHoggatt, AmberHoggatt, AmberHoggatt, AmberHoggatt, AmberHoggatt, AmberHoggatt, AmberChitteti, BrahmanandaChitteti, BrahmanandaChitteti, BrahmanandaChitteti, BrahmanandaChitteti, BrahmanandaChitteti, BrahmanandaSpeth, JenniferSpeth, JenniferSpeth, JenniferSpeth, JenniferSpeth, JenniferSpeth, JenniferHu, PeirongHu, PeirongHu, PeirongHu, PeirongHu, PeirongHu, PeirongPoteat, BradleyPoteat, BradleyPoteat, BradleyPoteat, BradleyPoteat, BradleyPoteat, BradleyStilger, KaylaStilger, KaylaStilger, KaylaStilger, KaylaStilger, KaylaStilger, KaylaFerraro, FrancescaFerraro, FrancescaFerraro, FrancescaFerraro, FrancescaFerraro, FrancescaFerraro, FrancescaSilberstein, LevSilberstein, LevSilberstein, LevSilberstein, LevSilberstein, LevSilberstein, LevWong, FrankieWong, FrankieWong, FrankieWong, FrankieWong, FrankieWong, FrankieFarag, SherifFarag, SherifFarag, SherifFarag, SherifFarag, SherifFarag, SherifCzader, MagdalenaCzader, MagdalenaCzader, MagdalenaCzader, MagdalenaCzader, MagdalenaCzader, MagdalenaMilne, GingerMilne, GingerMilne, GingerMilne, GingerMilne, GingerMilne, GingerBreyer, RichardBreyer, RichardBreyer, RichardBreyer, RichardBreyer, RichardBreyer, RichardSerezani, CarlosSerezani, CarlosSerezani, CarlosSerezani, CarlosSerezani, CarlosSerezani, CarlosScadden, DavidScadden, DavidScadden, DavidScadden, DavidScadden, DavidScadden, DavidGuise, TheresaGuise, TheresaGuise, TheresaGuise, TheresaGuise, TheresaGuise, TheresaSrour, EdwardSrour, EdwardSrour, EdwardSrour, EdwardSrour, EdwardSrour, EdwardPelus, LouisPelus, LouisPelus, LouisPelus, LouisPelus, Louis and Pelus, Louis
2013. | Journal Article
 
Prostaglandin E2 enhances long-term repopulation but does not permanently alter inherent stem cell competitiveness.
Hoggatt, JonathanMohammad, Khalid SSingh, Pratibha and Pelus, Louis M
Blood, vol. 122, (no. 17), pp. 2997-3000, 2013/Oct/24. | Journal Article
 
Recovery from hematopoietic injury by modulating prostaglandin E(2) signaling post-irradiation.
Hoggatt, JonathanSingh, PratibhaStilger, Kayla NPlett, P ASampson, Carol HChua, Hui LOrschell, Christie M and Pelus, Louis M
Blood cells, molecules & diseases, vol. 50, (no. 3), pp. 147-53, 2013/Mar. | Journal Article
2012
Blockade of prostaglandin E2 signaling through EP1 and EP3 receptors attenuates Flt3L-dependent dendritic cell development from hematopoietic progenitor cells.
Singh, PratibhaHoggatt, JonathanHu, PeirongSpeth, JenniferFukuda, SeijiBreyer, Richard M and Pelus, Louis M
Blood, vol. 119, (no. 7), pp. 1671-82, 2012/Feb/16. | Journal Article
2009
Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation.
Hoggatt, JonathanSingh, PratibhaSampath, Janardhan and Pelus, Louis M
Blood, vol. 113, (no. 22), pp. 5444-55, 2009/May/28. | Journal Article
 
Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal tandem duplication of Flt3.
Fukuda, SeijiSingh, PratibhaMoh, AkiraAbe, MarikoConway, Edward MBoswell, H SYamaguchi, SeijiFu, Xin Y and Pelus, Louis M
Blood, vol. 114, (no. 2), pp. 394-403, 2009/Jul/9. | Journal Article
2008
Vaccinia virus infection modulates the hematopoietic cell compartments in the bone marrow.
Singh, PratibhaSingh, PratibhaYao, YongxueYao, YongxueWeliver, AbigailWeliver, AbigailBroxmeyer, Hal EBroxmeyer, Hal EHong, Soon‐CheolHong, Soon-CheolChang, Cheong‐Hee and Chang, Cheong Hee
Stem cells (Dayton, Ohio), vol. 26, (no. 4), pp. 1009-1016, April 2008. | Journal Article
2007
Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II
Yao, YaoYao, YongxueLi, P.Li, PingSingh, P.Singh, PratibhaThiele, ATThiele, Allison TWilkes, David SWilkes, David SRenukaradhya, GJRenukaradhya, Gourapura JBrutkiewicz, Randy RBrutkiewicz, Randy RTravers, Jeffrey BTravers, Jeffrey BLuker, Gary DLuker, Gary DHong, SCHong, Soon-CheolBlum, Janice SBlum, Janice SChang, Cheong-Hee and Chang, Ch
Cellular Immunology, vol. 246, (no. 2), pp. 102, 2007. | Journal Article