Expertise

Research Interests:

  • Protein engineering with the goal of rescuing enzymes affected by disease causing mutations.

Research:

  • Dynamic Control of protein structure and function
  • Dynamic regulation of ligand binding by design of allosteric effectors
  • Modulation of hormone receptor specificity
  • Rescuing enzyme function using Fab chaperons
  • Generating bio-responsive nanostructures
  • Engineering Biosensors.
Communities
Biochemistry, Cellular Biochemistry, Molecular Biochemistry, Chemistry
Degrees
PhD, Duke University, Biochemistry, Protein Engineering, 2006
BS, Indiana University South Bend, Biological Sciences, 2000