101 Publications (Page 2 of 5)
2013
Abstract 4639: Blockade of MDM2-mediated signaling in context of DNA damage increases E2F1 expression and enhances cell death in triple-negative breast cancer cells
Tonsing-Carter, EvaTonsing-Carter, EvaShannon, Harlan EShannon, Harlan EBailey, Barbara JBailey, Barbara JMayo, Lindsey DMayo, Lindsey DPollok, Karen E and Pollok, Karen E
Cancer Research, vol. 73, (no. 8 Supplement), pp. 4639, 2013-04-15. | Journal Article
 
Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation.
Cheng, Ying-HuaHooker, R ANguyen, KhanhGerard-O'Riley, RitaWaning, David LChitteti, Brahmananda RMeijome, Tomas EChua, Hui LPlett, Artur POrschell, Christie MSrour, Edward FMayo, Lindsey DPavalko, Fredrick MBruzzaniti, Angela and Kacena, Melissa
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 28, (no. 6), pp. 1434-45, 2013/Jun. | Journal Article
 
Serdemetan antagonizes the Mdm2-HIF1α axis leading to decreased levels of glycolytic enzymes.
Lehman, Jason AHauck, Paula MGendron, Jaimie MBatuello, Christopher NEitel, Jacob AAlbig, AllanKadakia, Madhavi P and Mayo, Lindsey D
PloS one, vol. 8, (no. 9), pp. e74741, 2013. | Journal Article
 
Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways.
Wang, HaiyanWang, HaiyanCai, ShanbaoCai, ShanbaoErnstberger, AaronErnstberger, AaronBailey, Barbara JBailey, Barbara JWang, Michael ZWang, Michael ZCai, WenjingCai, WenjingGoebel, W ScottGoebel, W SCzader, Magdalena BCzader, Magdalena BCrean, ColinCrean, ColinSuvannasankha, AttayaSuvannasankha, AttayaShokolenkoc, InnaShokolenkoc, InnaWilson, Glenn LWilson, Glenn LBaluyut, Arthur RBaluyut, Arthur RMayo, Lindsey DMayo, Lindsey DPollok, Karen E and Pollok, Karen E
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 19, (no. 10), pp. 2699-709, 2013/May/15. | Journal Article
2012
Abstract 4671: Assessment of molecular processes relative to DNA damage response using primary human hematopoietic cells exposed to high-dose chemotherapy
Wang, HaiyanWang, HaiyanCai, ShanbaoCai, ShanbaoCai, WenjingCai, WenjingErnstberger, Aaron GErnstberger, Aaron GWang, Michael ZWang, Michael ZShokolenko, InnaShokolenko, InnaWilson, GlennWilson, GlennGoebel, W. ScottGoebel, W. ScottBaluyut, Arthur RBaluyut, Arthur RMayo, Lindsey DMayo, Lindsey DPollok, Karen E and Pollok, Karen E
Cancer Research, vol. 72, (no. 8 Supplement), pp. 4671, 2012-04-15. | Journal Article
 
Directing p53 to induce autophagy.
Mayo, Lindsey D
Cell cycle (Georgetown, Tex.), vol. 11, (no. 18), pp. 3353-4, 2012/Sep/15. | Journal Article
 
Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growth
Zhang, YiWeiZhang, QiZeng, Shelya XZhang, YuMayo, Lindsey D and Lu, Hua
Cancer Biology & Therapy, vol. 13, (no. 10), pp. 924, 8/1/2012. | Journal Article
 
Integration of DNA damage and repair with murine double-minute 2 (mdm2) in tumorigenesis.
Lehman, Jason A and Mayo, Lindsey D
International journal of molecular sciences, vol. 13, (no. 12), pp. 16373-86, 2012. | Journal Article
 
Megakaryocytes Regulate Expression of Pyk2 Isoforms and Caspase-mediated Cleavage of Actin in Osteoblasts
Kacena, Melissa AKacena, MelissaEleniste, Pierre PEleniste, Pierre PCheng, Ying-HuaCheng, Ying-HuaHuang, SuHuang, SuShivanna, MaheshShivanna, MaheshMeijome, Tomas EMeijome, Tomas EMayo, Lindsey DMayo, Lindsey DBruzzaniti, Angela and Bruzzaniti, Angela
The Journal of biological chemistry, vol. 287, (no. 21), pp. 17268, 2012-May-18. | Journal Article
2011
Abstract 2543: Humanized bone-marrow mouse model as a pre-clinical tool to assess therapy-mediated hematotoxicity
Cai, ShanbaoCai, ShanbaoWang, HaiyanWang, HaiyanBailey, BarbaraBailey, BarbaraErnstberger, AaronErnstberger, AaronJuliar, Beth EJuliar, Beth ESinn, Anthony LSinn, Anthony LChan, Rebecca JChan, Rebecca JJones, David RJones, David RMayo, Lindsey DMayo, Lindsey DBaluyut, Arthur RBaluyut, Arthur RGoebel, W SGoebel, W SPollok, Karen E and Pollok, Karen E
Cancer Research, vol. 71, (no. 8 Supplement), pp. 2543, 2011-04-15. | Journal Article
 
c-Abl phosphorylation of Mdm2 facilitates Mdm2-Mdmx complex formation.
Waning, David LLehman, Jason ABatuello, Christopher N and Mayo, Lindsey D
The Journal of biological chemistry, vol. 286, (no. 1), pp. 216-22, 2011/Jan/7. | Journal Article
 
Humanized Bone Marrow Mouse Model as a Preclinical Tool to Assess Therapy-Mediated Hematotoxicity
Cai, ShanbaoCai, ShanbaoWang, HaiyanWang, HaiyanBailey, BarbaraBailey, BarbaraErnstberger, AaronErnstberger, AaronJuliar, Beth EJuliar, Beth ESinn, Anthony LSinn, Anthony LChan, Rebecca JChan, Rebecca JJones, David RJones, David RMayo, Lindsey DMayo, Lindsey DBaluyut, Arthur RBaluyut, Arthur RGoebel, W SGoebel, W ScottPollok, Karen E and Pollok, Karen E
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 17, (no. 8), pp. 2206, 2011-Apr-15. | Journal Article
 
Induction of apoptotic genes by a p73-phosphatase and tensin homolog (p73-PTEN) protein complex in response to genotoxic stress.
Lehman, Jason AWaning, David LBatuello, Christopher NCipriano, RockyKadakia, Madhavi P and Mayo, Lindsey D
The Journal of biological chemistry, vol. 286, (no. 42), pp. 36631-36640, October 21, 2011. | Journal Article
2010
Abstract 5069: c-Abl contributes to Mdm2-Mdmx complex formation protecting p53 levels
Waning, David L and Mayo, Lindsey D
Cancer Research, vol. 70, (no. 8 Supplement), pp. 5069, 2010-04-15. | Journal Article
 
Abstract 5373: Modulation of temozolomide-mediated DNA damage in glioblastoma multiforme by the HDM2 antagonist, nutlin3
Wang, HaiyanWang, HaiyanWang, HaiyanCai, ShanbaoCai, ShanbaoCai, ShanbaoBailey, Barbara JBailey, Barbara JBailey, Barbara JSinn, Anthony LSinn, Anthony LSinn, Anthony LSilver, Jayne MSilver, Jayne MSilver, Jayne MMinto, Robert EMinto, Robert EMinto, Robert EGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MLong, Eric CLong, Eric CLong, Eric CSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DPollok, Karen EPollok, Karen E and Pollok, Karen E
Cancer Research, vol. 70, (no. 8 Supplement), pp. 5373, 2010-04-15. | Journal Article
 
Abstract 5373: Modulation of temozolomide-mediated DNA damage in glioblastoma multiforme by the HDM2 antagonist, nutlin3
Wang, HaiyanWang, HaiyanWang, HaiyanCai, ShanbaoCai, ShanbaoCai, ShanbaoBailey, Barbara JBailey, Barbara JBailey, Barbara JSinn, Anthony LSinn, Anthony LSinn, Anthony LSilver, Jayne MSilver, Jayne MSilver, Jayne MMinto, Robert EMinto, Robert EMinto, Robert EGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MLong, Eric CLong, Eric CLong, Eric CSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DPollok, Karen EPollok, Karen E and Pollok, Karen E
Cancer Research, vol. 70, (no. 8 Supplement), pp. 5373, 2010-04-15. | Journal Article
 
Inactivation of p53 signaling by p73 or PTEN ablation results in a transformed phenotype that remains susceptible to Nutlin-3 mediated apoptosis
Cipriano, RockyCipriano, RockyPatton, John TPatton, John TMayo, Lindsey DMayo, LindseyJackson, Mark W and Jackson, Mark
Cell Cycle, vol. 9, (no. 7), pp. 1379, 4/1/2010. | Journal Article
 
Inactivation of p53 signaling by p73 or PTEN ablation results in a transformed phenotype that remains susceptible to Nutlin-3 mediated apoptosis.
Cipriano, RockyCipriano, RockyPatton, John TPatton, John TMayo, Lindsey DMayo, LindseyJackson, Mark W and Jackson, Mark
Cell cycle (Georgetown, Tex.), vol. 9, (no. 7), pp. 1373-9, 2010/Apr/1. | Journal Article
 
TGF-[beta]1--induced expression of human Mdm2 correlates with late-stage metastatic breast cancer.(Research article)(transforming growth factors)
Araki, ShinakoAraki, ShinakoAraki, ShinakoAraki, ShinakoEitel, JacobEitel, JacobEitel, Jacob AEitel, Jacob ABatuello, ChristopherBatuello, Christopher NBatuello, ChristopherBatuello, Christopher NBijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehBijangi Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehXie, Xian JinXie, Xian-JinXie, Xian-JinXie, Xian-JinDanielpour, DavidDanielpour, DavidDanielpour, DavidDanielpour, DavidPollok, KarenPollok, Karen EPollok, Karen EPollok, KarenBoothman, DavidBoothman, DavidBoothman, David ABoothman, DavidMayo, Lindsey DMayo, LindseyMayo, Lindsey D and Mayo, Lindsey
Journal of Clinical Investigation, vol. 120, (no. 1), pp. 290, 20100101. | Journal Article
2009
Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.
Gama, VGomez, J AMayo, LindseyJackson, MarkDanielpour, DavidSong, KHaas, ArthurLaughlin, M J and Matsuyama, Shigemi
Cell death and differentiation, vol. 16, (no. 5), pp. 758-69, 2009/May. | Journal Article
 
PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells
Eitel, Jacob AEitel, Jacob ABijangi-Vishehsaraei, KhadijehBijangi-Vishehsaraei, KhadijehSaadatzadeh, M RSaadatzadeh, M. RezaBhavsar, Janak RMurphy, Michael PMurphy, Michael PPollok, Karen EPollok, Karen EMayo, Lindsey D and Mayo, Lindsey D
Cell Cycle, vol. 8, (no. 6), pp. 901, 3/15/2009. | Journal Article
 
Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domain
Yadavilli, SrideviMayo, Lindsey DHiggins, MaureenLain, SoniaHegde, Vijay and Deutsch, Walter A
DNA Repair, vol. 8, (no. 10), pp. 1224, 2009. | Journal Article
 
Up-Regulation of Hepatitis C Virus Replication and Production by Inhibition of MEK/ERK Signaling
Ndjomou, JeanNdjomou, JeanPark, In WooPark, In-wooLiu, YingLiu, YingMayo, Lindsey DMayo, Lindsey DHe, Johnny JHe, Johnny J and Jang, Sung K
PloS one, vol. 4, (no. 10), pp. e7498, 2009-Oct-16. | Journal Article
2008
Therapeutic considerations for Mdm2: not just a one trick pony
Lehman, Jason AEitel, Jacob ABatuello, Christopher N and Mayo, Lindsey D
Expert Opinion on Drug Discovery, vol. 3, (no. 11), pp. 1321, 11/1/2008. | Journal Article
2007
Hdm2 Is an Ubiquitin Ligase for the Anti-Apoptotic Protein Ku70
Gama, VivianGomez, Jose AMayo, Lindsey DHaas, Arthur L and Matsuyama, Shigemi
Blood, vol. 110, (no. 11), pp. 3347, 2007-11-16. | Journal Article