101 Publications (Page 2 of 5)
2013
Abstract 4639: Blockade of MDM2-mediated signaling in context of DNA damage increases E2F1 expression and enhances cell death in triple-negative breast cancer cellsTonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Pollok, Karen E and Pollok, Karen ECancer Research, vol. 73, (no. 8 Supplement), pp. 4639, 2013-04-15.
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Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation.Cheng, Ying-Hua⋅Hooker, R A⋅Nguyen, Khanh⋅Gerard-O'Riley, Rita⋅Waning, David L⋅Chitteti, Brahmananda R⋅Meijome, Tomas E⋅Chua, Hui L⋅Plett, Artur P⋅Orschell, Christie M⋅Srour, Edward F⋅Mayo, Lindsey D⋅Pavalko, Fredrick M⋅Bruzzaniti, Angela and Kacena, MelissaJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 28, (no. 6), pp. 1434-45, 2013/Jun.
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Serdemetan antagonizes the Mdm2-HIF1α axis leading to decreased levels of glycolytic enzymes.Lehman, Jason A⋅Hauck, Paula M⋅Gendron, Jaimie M⋅Batuello, Christopher N⋅Eitel, Jacob A⋅Albig, Allan⋅Kadakia, Madhavi P and Mayo, Lindsey DPloS one, vol. 8, (no. 9), pp. e74741, 2013.
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Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways.Wang, Haiyan⋅Wang, Haiyan⋅Cai, Shanbao⋅Cai, Shanbao⋅Ernstberger, Aaron⋅Ernstberger, Aaron⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Wang, Michael Z⋅Wang, Michael Z⋅Cai, Wenjing⋅Cai, Wenjing⋅Goebel, W Scott⋅Goebel, W S⋅Czader, Magdalena B⋅Czader, Magdalena B⋅Crean, Colin⋅Crean, Colin⋅Suvannasankha, Attaya⋅Suvannasankha, Attaya⋅Shokolenkoc, Inna⋅Shokolenkoc, Inna⋅Wilson, Glenn L⋅Wilson, Glenn L⋅Baluyut, Arthur R⋅Baluyut, Arthur R⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Pollok, Karen E and Pollok, Karen EClinical cancer research : an official journal of the American Association for Cancer Research, vol. 19, (no. 10), pp. 2699-709, 2013/May/15.
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2012
Abstract 4671: Assessment of molecular processes relative to DNA damage response using primary human hematopoietic cells exposed to high-dose chemotherapyWang, Haiyan⋅Wang, Haiyan⋅Cai, Shanbao⋅Cai, Shanbao⋅Cai, Wenjing⋅Cai, Wenjing⋅Ernstberger, Aaron G⋅Ernstberger, Aaron G⋅Wang, Michael Z⋅Wang, Michael Z⋅Shokolenko, Inna⋅Shokolenko, Inna⋅Wilson, Glenn⋅Wilson, Glenn⋅Goebel, W. Scott⋅Goebel, W. Scott⋅Baluyut, Arthur R⋅Baluyut, Arthur R⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Pollok, Karen E and Pollok, Karen ECancer Research, vol. 72, (no. 8 Supplement), pp. 4671, 2012-04-15.
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Directing p53 to induce autophagy.Mayo, Lindsey DCell cycle (Georgetown, Tex.), vol. 11, (no. 18), pp. 3353-4, 2012/Sep/15.
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Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growthZhang, YiWei⋅Zhang, Qi⋅Zeng, Shelya X⋅Zhang, Yu⋅Mayo, Lindsey D and Lu, HuaCancer Biology & Therapy, vol. 13, (no. 10), pp. 924, 8/1/2012.
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Integration of DNA damage and repair with murine double-minute 2 (mdm2) in tumorigenesis.Lehman, Jason A and Mayo, Lindsey DInternational journal of molecular sciences, vol. 13, (no. 12), pp. 16373-86, 2012.
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Megakaryocytes Regulate Expression of Pyk2 Isoforms and Caspase-mediated Cleavage of Actin in OsteoblastsKacena, Melissa A⋅Kacena, Melissa⋅Eleniste, Pierre P⋅Eleniste, Pierre P⋅Cheng, Ying-Hua⋅Cheng, Ying-Hua⋅Huang, Su⋅Huang, Su⋅Shivanna, Mahesh⋅Shivanna, Mahesh⋅Meijome, Tomas E⋅Meijome, Tomas E⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Bruzzaniti, Angela and Bruzzaniti, AngelaThe Journal of biological chemistry, vol. 287, (no. 21), pp. 17268, 2012-May-18.
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2011
Abstract 2543: Humanized bone-marrow mouse model as a pre-clinical tool to assess therapy-mediated hematotoxicityCai, Shanbao⋅Cai, Shanbao⋅Wang, Haiyan⋅Wang, Haiyan⋅Bailey, Barbara⋅Bailey, Barbara⋅Ernstberger, Aaron⋅Ernstberger, Aaron⋅Juliar, Beth E⋅Juliar, Beth E⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Jones, David R⋅Jones, David R⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Baluyut, Arthur R⋅Baluyut, Arthur R⋅Goebel, W S⋅Goebel, W S⋅Pollok, Karen E and Pollok, Karen ECancer Research, vol. 71, (no. 8 Supplement), pp. 2543, 2011-04-15.
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c-Abl phosphorylation of Mdm2 facilitates Mdm2-Mdmx complex formation.Waning, David L⋅Lehman, Jason A⋅Batuello, Christopher N and Mayo, Lindsey DThe Journal of biological chemistry, vol. 286, (no. 1), pp. 216-22, 2011/Jan/7.
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Humanized Bone Marrow Mouse Model as a Preclinical Tool to Assess Therapy-Mediated HematotoxicityCai, Shanbao⋅Cai, Shanbao⋅Wang, Haiyan⋅Wang, Haiyan⋅Bailey, Barbara⋅Bailey, Barbara⋅Ernstberger, Aaron⋅Ernstberger, Aaron⋅Juliar, Beth E⋅Juliar, Beth E⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Jones, David R⋅Jones, David R⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Baluyut, Arthur R⋅Baluyut, Arthur R⋅Goebel, W S⋅Goebel, W Scott⋅Pollok, Karen E and Pollok, Karen EClinical cancer research : an official journal of the American Association for Cancer Research, vol. 17, (no. 8), pp. 2206, 2011-Apr-15.
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Induction of apoptotic genes by a p73-phosphatase and tensin homolog (p73-PTEN) protein complex in response to genotoxic stress.Lehman, Jason A⋅Waning, David L⋅Batuello, Christopher N⋅Cipriano, Rocky⋅Kadakia, Madhavi P and Mayo, Lindsey DThe Journal of biological chemistry, vol. 286, (no. 42), pp. 36631-36640, October 21, 2011.
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2010
Abstract 5069: c-Abl contributes to Mdm2-Mdmx complex formation protecting p53 levelsWaning, David L and Mayo, Lindsey DCancer Research, vol. 70, (no. 8 Supplement), pp. 5069, 2010-04-15.
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Abstract 5373: Modulation of temozolomide-mediated DNA damage in glioblastoma multiforme by the HDM2 antagonist, nutlin3Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Cai, Shanbao⋅Cai, Shanbao⋅Cai, Shanbao⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, Jayne M⋅Minto, Robert E⋅Minto, Robert E⋅Minto, Robert E⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Pollok, Karen E⋅Pollok, Karen E and Pollok, Karen ECancer Research, vol. 70, (no. 8 Supplement), pp. 5373, 2010-04-15.
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Abstract 5373: Modulation of temozolomide-mediated DNA damage in glioblastoma multiforme by the HDM2 antagonist, nutlin3Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Cai, Shanbao⋅Cai, Shanbao⋅Cai, Shanbao⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, Jayne M⋅Minto, Robert E⋅Minto, Robert E⋅Minto, Robert E⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Pollok, Karen E⋅Pollok, Karen E and Pollok, Karen ECancer Research, vol. 70, (no. 8 Supplement), pp. 5373, 2010-04-15.
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Inactivation of p53 signaling by p73 or PTEN ablation results in a transformed phenotype that remains susceptible to Nutlin-3 mediated apoptosisCipriano, Rocky⋅Cipriano, Rocky⋅Patton, John T⋅Patton, John T⋅Mayo, Lindsey D⋅Mayo, Lindsey⋅Jackson, Mark W and Jackson, MarkCell Cycle, vol. 9, (no. 7), pp. 1379, 4/1/2010.
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Inactivation of p53 signaling by p73 or PTEN ablation results in a transformed phenotype that remains susceptible to Nutlin-3 mediated apoptosis.Cipriano, Rocky⋅Cipriano, Rocky⋅Patton, John T⋅Patton, John T⋅Mayo, Lindsey D⋅Mayo, Lindsey⋅Jackson, Mark W and Jackson, MarkCell cycle (Georgetown, Tex.), vol. 9, (no. 7), pp. 1373-9, 2010/Apr/1.
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TGF-[beta]1--induced expression of human Mdm2 correlates with late-stage metastatic breast cancer.(Research article)(transforming growth factors)Araki, Shinako⋅Araki, Shinako⋅Araki, Shinako⋅Araki, Shinako⋅Eitel, Jacob⋅Eitel, Jacob⋅Eitel, Jacob A⋅Eitel, Jacob A⋅Batuello, Christopher⋅Batuello, Christopher N⋅Batuello, Christopher⋅Batuello, Christopher N⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Xie, Xian Jin⋅Xie, Xian-Jin⋅Xie, Xian-Jin⋅Xie, Xian-Jin⋅Danielpour, David⋅Danielpour, David⋅Danielpour, David⋅Danielpour, David⋅Pollok, Karen⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen⋅Boothman, David⋅Boothman, David⋅Boothman, David A⋅Boothman, David⋅Mayo, Lindsey D⋅Mayo, Lindsey⋅Mayo, Lindsey D and Mayo, LindseyJournal of Clinical Investigation, vol. 120, (no. 1), pp. 290, 20100101.
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2009
Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.Gama, V⋅Gomez, J A⋅Mayo, Lindsey⋅Jackson, Mark⋅Danielpour, David⋅Song, K⋅Haas, Arthur⋅Laughlin, M J and Matsuyama, ShigemiCell death and differentiation, vol. 16, (no. 5), pp. 758-69, 2009/May.
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PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cellsEitel, Jacob A⋅Eitel, Jacob A⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Saadatzadeh, M R⋅Saadatzadeh, M. Reza⋅Bhavsar, Janak R⋅Murphy, Michael P⋅Murphy, Michael P⋅Pollok, Karen E⋅Pollok, Karen E⋅Mayo, Lindsey D and Mayo, Lindsey DCell Cycle, vol. 8, (no. 6), pp. 901, 3/15/2009.
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Ribosomal protein S3: A multi-functional protein that interacts with both p53 and MDM2 through its KH domainYadavilli, Sridevi⋅Mayo, Lindsey D⋅Higgins, Maureen⋅Lain, Sonia⋅Hegde, Vijay and Deutsch, Walter ADNA Repair, vol. 8, (no. 10), pp. 1224, 2009.
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Up-Regulation of Hepatitis C Virus Replication and Production by Inhibition of MEK/ERK SignalingNdjomou, Jean⋅Ndjomou, Jean⋅Park, In Woo⋅Park, In-woo⋅Liu, Ying⋅Liu, Ying⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅He, Johnny J⋅He, Johnny J and Jang, Sung KPloS one, vol. 4, (no. 10), pp. e7498, 2009-Oct-16.
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2008
Therapeutic considerations for Mdm2: not just a one trick ponyLehman, Jason A⋅Eitel, Jacob A⋅Batuello, Christopher N and Mayo, Lindsey DExpert Opinion on Drug Discovery, vol. 3, (no. 11), pp. 1321, 11/1/2008.
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2007
Hdm2 Is an Ubiquitin Ligase for the Anti-Apoptotic Protein Ku70Gama, Vivian⋅Gomez, Jose A⋅Mayo, Lindsey D⋅Haas, Arthur L and Matsuyama, ShigemiBlood, vol. 110, (no. 11), pp. 3347, 2007-11-16.
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