Our current interest is the function of a single gene, let-7-Complex, which encodes three different and highly conserved microRNAs (mir-100, let-7 and miR-125).
The Sokol lab exploits the genetically tractable fly model system to study the heterochronic pathway, which includes the LIN-28 RNA binding protein and the let-7 microRNA and controls stem cell fate and differentiation in response to environmental cues.
Projects:
- Translational control of stem cell behavior
- microRNAs in stem cell fate and differentiation
- Uncovering microRNA pathways.
Research:
- Regulatory RNA pathways in Stem cells and differentiation.
Subject Area:
Research Interests:
- regulatory RNA pathways in stem cells and differentiation.