192 Publications (Page 1 of 8)
2023
Engineering Metastability into a Virus-like Particle to Enable Triggered Dissociation. Journal of the American Chemical Society
. | Journal Article
 
New tricks for old molecules: A newly discovered modality for CAMs may yet lead to an HBV cure. Hepatology
. | Journal Article
 
Structure of the Hepatitis B virus capsid quasi-6-fold with a trapped C-terminal domain reveals capsid movements associated with domain exit. Journal of Biological Chemistry
. | Journal Article
2022
Core Protein-Directed Antivirals and Importin \upbeta Can Synergistically Disrupt HBV Capsids
Kim, ChristineBarnes, Lauren F.Schlicksup, Christopher J.Patterson, Angela J.Bothner, Brian B.Jarrold, Martin F.Wang, Che-Yen Joseph and Zlotnick, Adam
Journal of Virology. | Journal Article
 
Core Protein-Directed Antivirals and Importin \upbeta Can Synergistically Disrupt Hepatitis B Virus Capsids
Kim, ChristineBarnes, Lauren F.Schlicksup, Christopher J.Patterson, Angela J.Bothner, BrianJarrold, Martin F.Wang, Che-Yen Joseph and Zlotnick, Adam
Journal of Virology, vol. 96. | Journal Article
 
Hysteresis in Hepatitis B Virus (HBV) Requires Assembly of Near-Perfect Capsids
Biochemistry. | Journal Article
 
In-Plane, In-Series Nanopores with Circular Cross Sections for Resistive-Pulse Sensing
Zhang, MiHarms, Zachary D.Greibe, TineStarr, Caleb A.Zlotnick, Adam and Jacobson, Stephen C.
ACS Nano. | Journal Article
 
Nomenclature of HBV core protein-targeting antivirals. Nature Reviews Gastroenterology & Hepatology
2021
Asymmetrizing an icosahedral virus capsid by hierarchical assembly of subunits with designed asymmetry
Zhang, MiZhang, MiLyktey, Nicholas ALyktey, Nicholas AJarrold, Martin FJarrold, Martin FJacobson, Stephen CJacobson, Stephen CZlotnick, Adam and Zlotnick, Adam
Nature Communications. | Journal Article
 
Core Protein-Directed Antivirals and Importinβ Can Synergistically Disrupt HBV Capsids
 
Disassembly of Single Virus Capsids Monitored in Real Time with Multicycle Resistive-Pulse Sensing
Analytical Chemistry. | Journal Article
 
HBV Core Protein Is in Flux between Cytoplasmic, Nuclear, and Nucleolar Compartments
mBio. | Journal Article
 
Virus self-assembly proceeds through contact-rich energy minima
Science Advances. | Journal Article
2020
Dynamics of Hepatitis B virus capsid protein dimer regulate assembly through an allosteric network
Patterson, AngelaZhao, ZhongchaoWaymire, ElizabethZlotnick, Adam and Bothner, Brian
ACS Chemical Biology. | Journal Article
 
Higher Resolution Charge Detection Mass Spectrometry
Analytical Chemistry. | Journal Article
 
Local stabilization of subunit-subunit contacts causes global destabilization of Hepatitis B virus capsids
Schlicksup, Christopher JohnLaughlin, PatrickDunkelbarger, StevenWang, Joseph Che-Yen and Zlotnick, Adam
ACS Chemical Biology. | Journal Article
 
Rapidly Forming Early Intermediate Structures Dictate the Pathway of Capsid Assembly
Asor, RoiSchlicksup, Christopher JohnZhao, ZhongchaoZlotnick, Adam and Raviv, Uri
Journal of the American Chemical Society. | Journal Article
 
Revealing in real-time a multistep assembly mechanism for SV40 virus-like particles
Science Advances. | Journal Article
 
The integrity of the intradimer interface of the Hepatitis B Virus capsid protein dimer regulates capsid self-assembly
Zhao, ZhongchaoHadden Perilla, J.A.Zlotnick, A.Wang, Joseph Che-YenSegura, Carolina PerezZhao, Z.Wang, J.C.-Y.Hadden-Perilla, Jodi ASegura, C.P. and Zlotnick, Adam
ACS Chemical Biology. | Journal Article
 
Uncovering the Self-Assembly Mechanism of Hepatitis B Virus at the Single-Molecule Level
Buzón, PedroMaity, SouravChristodoulis, PanagiotisWiertsema, Monique JDunkelbarger, StevenKim, ChristineWuite, Gijs JZlotnick, Adam and Roos, Wouter H
Biophysical Journal, vol. 118, (no. 3), pp. 200a, 2020-02-07. | Journal Article
2019
Analytical Techniques to Characterize the Structure, Properties, and Assembly of Virus Capsids
Kondylis, PanagiotisKondylis, PanagiotisSchlicksup, Christopher JSchlicksup, Christopher JZlotnick, AdamZlotnick, AdamJacobson, Stephen C and Jacobson, Stephen C
Analytical chemistry, vol. 91, (no. 1), pp. 636, 2019-Jan-02. | Journal Article
 
Assembly Reactions of Hepatitis B Capsid Protein into Capsid Nanoparticles Follow a Narrow Path Through a Complex Reaction Landscape
Asor, RoiAsor, RoiSelzer, LisaSelzer, LisaSchlicksup, Christopher JohnSchlicksup, Christopher JohnZhao, ZhongchaoZhao, ZhongchaoZlotnick, AdamZlotnick, AdamRaviv, Uri and Raviv, Uri
ACS nano, vol. 13, (no. 7), pp. 7626, 2019-Jun-07. | Journal Article
 
Competition between Normative and Drug-Induced Virus Self-Assembly Observed with Single-Particle Methods
Kondylis, PanagiotisKondylis, PanagiotisSchlicksup, Christopher JSchlicksup, Christopher JBrunk, Nicholas EBrunk, Nicholas EZhou, JinshengZhou, JinshengZlotnick, AdamZlotnick, AdamJacobson, Stephen C and Jacobson, Stephen C
Journal of the American Chemical Society, vol. 141, (no. 3), pp. 1260, 2019-Jan-23. | Journal Article
 
Evolution of Intermediates during Capsid Assembly of Hepatitis B Virus with Phenylpropenamide-Based Antivirals
Kondylis, PanagiotisKondylis, PanagiotisSchlicksup, Christopher JSchlicksup, Christopher JKaten, Sarah PKaten, Sarah PLee, Lye SiangLee, Lye SiangZlotnick, AdamZlotnick, AdamJacobson, Stephen C and Jacobson, Stephen C
ACS infectious diseases, vol. 5, (no. 5), pp. 777, 2019-May-10. | Journal Article
 
Identification of Chikungunya virus nucleocapsid core assembly modulators
Jones-Burrage, Sara E.Tan, ZhenningLi, LichunZlotnick, Adam and Mukhopadhyay, Suchetana
Cold Spring Harbor Laboratory