203 Publications (Page 4 of 9)
2009
Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells
Vascotto, Carlo⋅Cesaratto, Laura⋅Zeef, Leo A⋅Deganuto, Marta⋅D'Ambrosio, Chiara⋅Scaloni, Andrea⋅Romanello, Milena⋅Damante, Giuseppe⋅Taglialatela, Giulio⋅Delneri, Daniela⋅Kelley, Mark R⋅Mitra, Sankar⋅Quadrifoglio, Franco and Tell, Gianluca
Proteomics., vol. 9, (no. 4), pp. 1058-1074, 2009. | Journal Article
 
Going ape as an approach to cancer therapeutics.
Bapat, Aditi⋅Bapat, Aditi⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Kelley, Mark and Kelley, Mark R
Antioxidants & redox signaling, vol. 11, (no. 3), pp. 651-68, 2009/Mar. | Journal Article
 
Role of Ape1 and Base Excision Repair in the Radiation Response and Heat-radiosensitization of HeLa Cells
Batuello, Christopher N⋅Batuello, Christopher N⋅Kelley, Mark R⋅Kelley, Mark R⋅Dynlacht, Joseph R and Dynlacht, Joseph R
Anticancer research, vol. 29, (no. 4), pp. 1325, 2009-04-01. | Journal Article
 
Role of Ape1 and base excision repair in the radioresponse and heat-radiosensitization of HeLa Cells.
Batuello, Christopher N⋅Kelley, Mark R and Dynlacht, Joseph R
Anticancer research, vol. 29, (no. 4), pp. 1319-25, 2009/Apr. | Journal Article
 
Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: Use of APE1 small molecule inhibitors to delineate APE1 functions
Jiang, Yanlin⋅Jiang, Y.⋅Guo, C.⋅Guo, Chunlu⋅Fishel, Melissa L⋅Fishel, ML⋅Wang, ZY⋅Wang, Zheng-Yu⋅Vasko, Michael R⋅Vasko, Michael R⋅Kelley, Mark R and Kelley, Mark R
DNA Repair, vol. 8, (no. 11), pp. 1273-1282, 2009. | Journal Article
 
Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation.
Reed, April M⋅Reed, April M⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Kelley, Mark R and Kelley, Mark
Future oncology (London, England), vol. 5, (no. 5), pp. 713-26, 2009/Jun. | Journal Article
 
The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme
Tell, G.⋅Quadrifoglio, F.⋅Tiribelli, C. and Kelley, Mark R
Antioxidants and Redox Signaling, vol. 11, (no. 3), pp. 601-619, 2009. | Journal Article
2008
DNA Repair Proteins as Molecular Targets for Cancer Therapeutics
Kelley, Mark R⋅Kelley, Mark⋅Fishel, Melissa L and Fishel, Melissa
Anti-Cancer Agents in Medicinal Chemistry, vol. 8, (no. 4), pp. 417-425, 2008. | Journal Article
 
Enhancement of Cisplatin [cis-Diammine Dichloroplatinum (II)] Cytotoxicity by O6-Benzylguanine Involves Endoplasmic Reticulum Stress
Rabik, Cara⋅Rabik, Cara A⋅Rabik, Cara⋅Fishel, Melissa⋅Fishel, Melissa L⋅Fishel, Melissa⋅Holleran, Julianne⋅Holleran, Julianne⋅Holleran, Julianne L⋅Kasza, Kristen⋅Kasza, Kristen⋅Kasza, Kristen⋅Kelley, Mark⋅Kelley, Mark R⋅Kelley, Mark⋅Egorin, Merrill⋅Egorin, Merrill⋅Egorin, Merrill J⋅Dolan, M.⋅Dolan, M. and Dolan, M. E
Journal of Pharmacology and Experimental Therapeutics, vol. 327, (no. 2), pp. 452, 20081101. | Journal Article
 
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
Georgiadis, Millie M⋅Luo, M.⋅Gaur, RK⋅Delaplane, S.⋅Li, Xiaoman and Kelley, Mark R
Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, vol. 643, (no. 1-2), pp. 54-63, 2008. | Journal Article
 
Implications of apurinic/apyrimidinic endonuclease in reactive oxygen signaling response after cisplatin treatment of dorsal root ganglion neurons.
Jiang, Yanlin⋅Guo, Chunlu⋅Vasko, Michael R and Kelley, Mark
Cancer research, vol. 68, (no. 15), pp. 6425-34, 2008/Aug/1. | Journal Article
 
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, ML⋅He, Ying⋅He, Ying⋅He, Y.⋅Reed, April M⋅Reed, April M⋅Reed, AM⋅Chin-Sinex, Helen⋅Chin-Sinex, H.⋅Chin-Sinex, Helen⋅Hutchins, Gary D⋅Hutchins, Gd⋅Hutchins, Gary D⋅Mendonca, Marc S⋅Mendonca, MS⋅Mendonca, Marc S⋅Kelley, Mark R⋅Kelley, Mark R and Kelley, Mark R
DNA Repair, vol. 7, (no. 2), pp. 177-186, 2008. | Journal Article
 
Role of the Multifunctional DNA Repair and Redox Signaling Protein Ape1/Ref-1 in Cancer and Endothelial Cells: Small-Molecule Inhibition of the Redox Function of Ape1
Luo, M.⋅Luo, Meihua⋅Delaplane, Sarah⋅Delaplane, S.⋅Jiang, Aihua⋅Jiang, A.⋅Reed, April⋅Reed, A.⋅He, Y.⋅He, Ying⋅Fishel, Melissa⋅Fishel, M.⋅Nyland, 2nd, Rodney L⋅Nyland, RL I⋅Borch, Richard F⋅Borch, Rich F⋅Qiao, X.⋅Qiao, Xiaoxi⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Kelley, Mark R and Kelley, Mark R
Antioxidants and Redox Signaling, vol. 10, (no. 11), pp. 1853-1867, 2008. | Journal Article
2007
Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress.
Deganuto, Marta⋅Deganuto, M.⋅Pittis, Maria G⋅Pittis, M.G.⋅Pines, Alex⋅Pines, A.⋅Dominissini, Silvia⋅Dominissini, S.⋅Kelley, Mark⋅Kelley, M.R.⋅Garcia, R.⋅Garcia, Rodolfo⋅Quadrifoglio, F.⋅Quadrifoglio, Franco⋅Bembi, Bruno⋅Bembi, B.⋅Tell, Gianluca and Tell, G.
Journal of cellular physiology, vol. 212, (no. 1), pp. 223-35, 2007/Jul. | Journal Article
 
Altering DNA base excision repair: Use of nuclear and mitochondrial-targeted N-methylpurine DNA glycosylase to sensitize astroglia to chemotherapeutic agents
Harrison, Jason F⋅Rinne, Mikael L⋅Kelley, Mark R⋅Druzhyna, Nadiya M⋅Wilson, Glenn L⋅Le Doux, Susan P and Ledoux, Susan P
Glia, vol. 55, (no. 14), pp. 1416-1425, 2007. | Journal Article
 
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain.
Zou, Gang-Ming⋅Luo, Mei-Hua⋅Reed, April⋅Kelley, Mark and Yoder, Mervin C
Blood, vol. 109, (no. 5), pp. 1917-22, 2007/Mar/1. | Journal Article
 
Constitutional polymorphisms of prostate cancer: prognostic and diagnostic implications
Hahn, Noah⋅Hahn, Noah M⋅Kelley, Mark R⋅Kelley, Mark R⋅Klaunig, James E⋅Klaunig, James E⋅Koch, Michael O⋅Koch, Michael O⋅Li, Lang⋅Li, Lang⋅Sweeney, Christopher J and Sweeney, Christopher J
Future Oncology, vol. 3, (no. 6), pp. 682, 2007-December-01. | Journal Article
 
DNA repair in neurons: so if they don't divide what's to repair?
Fishel, Melissa L⋅Fishel, Melissa L⋅Vasko, Michael R⋅Vasko, Michael R⋅Kelley, Mark and Kelley, Mark R
Mutation research, vol. 614, (no. 1-2), pp. 24-36, 2007/Jan/3. | Journal Article
 
Inhibition of the Redox Function of Ape-1/ref-1 in Myeloid Leukemia Cells Results in Enhanced Sensitivity to Retinoic Acid Induced Differentiation and Apoptosis
Robertson, Kent A⋅Robertson, Kent A⋅Colvin, Edwin S⋅Colvin, Edwin S⋅Kelley, Mark R and Kelley, Mark R
Blood, vol. 110, (no. 11), pp. 4217, 2007-11-16. | Journal Article
 
Manipulation of Base Excision Repair to Sensitize Ovarian Cancer Cells to Alkylating Agent Temozolomide
Fishel, Melissa L⋅Fishel, Melissa⋅He, Ying⋅He, Ying⋅Smith, Martin L⋅Smith, Martin⋅Kelley, Mark R and Kelley, Mark
Clinical Cancer Research, vol. 13, (no. 1), pp. 260-267, 2007. | Journal Article
 
Potentiation of Melphalan-Induced Cytotoxicity through Targeting of the Base Excision Repair Pathway in Multiple Myeloma
Reed, April M⋅Reed, April M⋅Reed, April M⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Kelley, Mark R⋅Kelley, Mark R⋅Kelley, Mark R⋅Abonour, Rafat⋅Abonour, Rafat and Abonour, Rafat
Blood, vol. 110, (no. 11), pp. 4799, 2007-11-16. | Journal Article
 
Repression of cyclin D1 as a target for germ cell tumors.
Freemantle, Sarah⋅Vaseva, Angelina V⋅Ewings, Katherine E⋅Bee, Thomas⋅Krizan, Katey A⋅Kelley, Mark R⋅Hattab, Eyas M⋅Memoli, Vincent A⋅Black, Candice C⋅Spinella, Michael J and Dmitrovsky, Ethan
International journal of oncology, vol. 30, (no. 2), pp. 333-40, 2007/Feb. | Journal Article
 
The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target
Fishel, Melissa L⋅Fishel, Melissa L⋅Kelley, Mark R and Kelley, Mark R
Molecular Aspects of Medicine, vol. 28, (no. 3), pp. 395, 2007. | Journal Article
 
Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
Ho, Renee⋅Rachek, Lyudmila I⋅Xu, Yi⋅Kelley, Mark R⋅Le Doux, Susan P and Wilson, Glenn L
Journal of Neurochemistry, vol. 102, (no. 1), pp. 13-24, Jul 2007. | Journal Article
2006
Accelerated repair and reduced mutagenicity of oxidative DNA damage in human bladder cells expressing the E. coli FPG protein
Ropolo, Monica⋅Geroldi, Alessandro⋅Degan, Paolo⋅Andreotti, Virginia⋅Zupo, Simona⋅Poggi, Alessandro⋅Reed, April⋅Kelley, Mark R and Frosina, Guido
International Journal of Cancer, vol. 118, (no. 7), pp. 1634, 1 April 2006. | Journal Article