The basic question my research addresses is how supra-molecular structures are constructed: How does programmed expression of information encoded in linear form in the genome result in achievement of functional three dimensional cellular morphology? We study this question at two very different levels: in cells, and in evolution.
The basic question my research addresses is how supra-molecular structures are constructed: How does programmed expression of information encoded in linear form in the genome result in achievement of functional three dimensional cellular morphology? We study this question at two very different levels: in cells, and in evolution.
The broad aim of our research is to determine how these various factors combine to control microtubule assembly and function in vivo.
Current research combines proteomic and genetic analysis to identify and characterize proteins that interact with the axoneme tubulins to generate the complex axonemal architecture.
Research Interests:
- developmental mechanisms and regulation in eukaryotic systems; eukaryotic cell biology, cytoskeleton and signaling; evolution
