30 Publications (Page 1 of 2)
2022
Hereditary spastic paraplegia SPG13 mutation increases structural stability and ATPase activity of human mitochondrial chaperoninChen, Lingling⋅Syed, Aiza and Balaji, AdhityaScientific Reports (Nature Publisher Group), vol. 12, (no. 1), 2022.
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2021
Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60Chen, LinglingScientific Reports (Nature Publisher Group), vol. 11, (no. 1), 2021.
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2020
The Immunosuppressive Niche of Soft Tissue Sarcomas is Sustained by Tumor Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid StructuresChen, Lingling⋅Oke, Teniola⋅Siegel, Nicholas⋅Cojocaru, Gady⋅Tam, Ada J⋅Blosser, Richard L⋅Swailes, Jessica⋅Ligon, John Allen⋅Lebid, Andriana⋅Morris, Carol⋅Levin, Adam⋅Rhee, Daniel S⋅Johnston, Fabian M⋅Greer, Jonathan B⋅Meyer, Christian F⋅Ladle, Brian H⋅Thompson, Elizabeth D⋅Montgomery, Elizabeth A⋅Choi, Woonyoung⋅McConkey, David J⋅Anders, Robert A⋅Pardoll, Drew M and Llosa, Nicolas JClinical cancer research : an official journal of the American Association for Cancer Research, pp. clincanres.3416.2019, 2020-Apr-24.
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2019
Cloning and functional analysis of squalene synthase gene from Dryopteris fragrans (L.) SchottGao, Rui⋅Yu, Dan⋅Chen, Lingling⋅Wang, Wenzong⋅Sun, Lili and Chang, YingProtein Expression and Purification, vol. 155, pp. 103, March 2019.
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2017
Biochemical and Genetic Analysis of the Chlamydia GroEL ChaperoninsIllingworth, Melissa⋅Hooppaw, Anna J⋅Ruan, Lu⋅Fisher, Derek J and Chen, LinglingJournal of bacteriology, vol. 199, (no. 12), pp. E00844, 2017-06-15.
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Creating the Functional Single-Ring GroEL-GroES Chaperonin Systems via Modulating GroEL-GroES InteractionIllingworth, Melissa⋅Ellis, Holly and Chen, LinglingScientific reports, vol. 7, (no. 1), pp. 11, 2017-08-29.
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2015
Effective ATPase activity and moderate chaperonin-cochaperonin interaction are important for the functional single-ring chaperonin system.Illingworth, Melissa⋅Salisbury, Jared⋅Li, Wenqian⋅Lin, Donghai and Chen, LinglingBiochemical and biophysical research communications, vol. 466, (no. 1), pp. 15-20, October 9, 2015.
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2013
In vivo analysis of DNA binding and ligand interaction of BlcR, an IclR-type repressor from Agrobacterium tumefaciens.Pan, Yi⋅Pan, Yi⋅Wang, Yi⋅Wang, Yi⋅Fuqua, Clay⋅Fuqua, Clay⋅Chen, Lingling and Chen, LinglingMicrobiology (Reading, England), vol. 159, pp. 814-822, April 2013.
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2012
The quorum sensing transcriptional regulator TraR has separate binding sites for DNA and the anti-activatorZheng, Zhida⋅Zheng, Zhida⋅Fuqua, Clay⋅Fuqua, Clay⋅Chen, Lingling and Chen, LinglingBiochemical and Biophysical Research Communications, vol. 418, (no. 2), pp. 401, 2012-02-10.
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The transiently ordered regions in intrinsically disordered ExsE are correlated with structural elements involved in chaperone binding.Zheng, Zhida⋅Ma, Dejian⋅Yahr, Timothy L and Chen, LinglingBiochemical and biophysical research communications, vol. 417, (no. 1), pp. 129-34, 2012/Jan/6.
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2011
Stimulating the substrate folding activity of a single ring GroEL variant by modulating the cochaperonin GroES.Illingworth, Melissa⋅Ramsey, Andrew⋅Zheng, Zhida and Chen, LinglingThe Journal of biological chemistry, vol. 286, (no. 35), pp. 30401-8, 2011/Sep/2.
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Structural basis of acyl-homoserine lactone-dependent signaling.Churchill, Mair E and Chen, LinglingChemical reviews, vol. 111, (no. 1), pp. 68-85, 2011/Jan/12.
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The Agrobacterium tumefaciens transcription factor BlcR is regulated via oligomerization.Pan, Yi⋅Fiscus, Valena⋅Meng, Wuyi⋅Zheng, Zhida⋅Zhang, Lian Hui⋅Fuqua, Clay and Chen, LinglingThe Journal of biological chemistry, vol. 286, (no. 23), pp. 20431-40, 2011/Jun/10.
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2010
Analysis of peptides and proteins in their binding to GroEL.Li, Yali⋅Zheng, Zhida⋅Ramsey, Andrew and Chen, LinglingJournal of peptide science : an official publication of the European Peptide Society, vol. 16, (no. 12), pp. 693-700, 2010/Dec.
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Signal Synthesis for a Rapid ResponseChen, LinglingStructure, vol. 18, (no. 9), pp. 1072-1073, 2010.
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2009
GroEL Recognizes an Amphipathic Helix and Binds to the Hydrophobic Side.Li, Yali⋅Li, Yali⋅Gao, Xinfeng⋅Gao, Xinfeng⋅Chen, Lingling and Chen, LinglingThe Journal of biological chemistry, vol. 284, (no. 7), pp. 4324-31, 2009/Feb/13.
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2007
Biochemical Characterization of a Regulatory Cascade Controlling Transcription of the Pseudomonas aeruginosa Type III Secretion SystemZheng, Zhida⋅Zheng, Zhida⋅Zheng, Zhida⋅Chen, Guozhou⋅Chen, Guozhou⋅Chen, Guozhou⋅Joshi, Shreyas⋅Joshi, Shreyas⋅Joshi, Shreyas⋅Brutinel, Evan D⋅Brutinel, Evan D⋅Brutinel, Evan⋅Yahr, Timothy L⋅Yahr, Timothy⋅Yahr, Timothy L⋅Chen, Lingling⋅Chen, Lingling and Chen, LinglingJournal of Biological Chemistry, vol. 282, (no. 9), pp. 6142, 20070302.
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Biochemical Characterization of a Regulatory Cascade Controlling Transcription of the Pseudomonas aeruginosa Type III Secretion SystemZheng, Zhida⋅Chen, Guozhou⋅Joshi, Shreyas⋅Brutinel, Evan D⋅Yahr, Timothy L and Chen, LinglingJournal of Biological Chemistry, vol. 282, (no. 9), pp. 6136-6142, 2007.
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Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein familyBanga, Simran⋅Gao, Ping⋅Shen, Xihui⋅Fiscus, Valena⋅Zong, Wei Xing⋅Chen, Lingling and Luo, Zhao QingProceedings of the National Academy of Sciences, USA, vol. 104, (no. 12), pp. 5121-5126, 2007.
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Structural basis for antiactivation in bacterial quorum sensingChen, Guozhou⋅Jeffrey, Philip D⋅Fuqua, Clay⋅Shi, Yigong and Chen, LinglingProceedings of the National Academy of Sciences of the United States of America, vol. 104, (no. 42), Oct 16, 2007.
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2006
Characterization of ExsC and ExsD Self-Association and Heterocomplex FormationLykken, Guinevere L⋅Chen, GuoZhou⋅Brutinel, Evan D⋅Chen, Lingling and Yahr, Timothy LJournal of Bacteriology, vol. 188, (no. 19), pp. 6832, Oct 2006.
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Crystal Structure and Mechanism of TraM2, a Second Quorum-Sensing Antiactivator of Agrobacterium tumefaciens Strain A6Chen, Guozhou⋅Wang, Chao⋅Fuqua, Clay⋅Zhang, Lian Hui and Chen, LinglingJournal of Bacteriology, vol. 188, (no. 23), pp. 8244-8251, 2006.
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Dual Control of Quorum Sensing by Two TraM-Type Antiactivators in Agrobacterium tumefaciens Octopine Strain A6Wang, Chao⋅Zhang, Hai-Bao⋅Chen, Guozhou⋅Chen, Lingling and Zhang, Lian HuiJournal of Bacteriology, vol. 188, (no. 7), pp. 2435-2445, Apr 2006.
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Dual control of quorum sensing by two TraM-type antiactivators in Agrobacterium turnefaciens octopine strain A6Wang, Chao⋅Zhang, Hai-Bao⋅Chen, Guozhou⋅Chen, Lingling and Zhang, Lian-HuiJournal of Bacteriology, vol. 188, (no. 7-8), pp. 2435, 20060401.
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2004
Quorum-sensing antiactivator TraM forms a dimer that dissociates to inhibit TraRChen, G.⋅Malenkos, JW⋅Cha, M.⋅Fuqua, Clay and Chen, LinglingMolecular Microbiology, vol. 52, (no. 6), pp. 1641-1651, 2004.
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