185 Publications (Page 6 of 8)
2007
Structure-activity relationships of beta-MSH derived melanocortin-4 receptor peptide agonists.
Yan, Liang Z⋅Hsiung, Hansen M⋅Heiman, Mark L⋅Gadski, Robert A⋅Emmerson, Paul J⋅Hertel, JeAnne⋅Flora, David⋅Edwards, Patrick⋅Smiley, Dave⋅Zhang, Lianshan⋅Husain, Saba⋅Kahl, Steven D⋅DiMarchi, Richard D and Mayer, John P
Current topics in medicinal chemistry, vol. 7, (no. 11), pp. 1052-67, 2007. | Journal Article
2006
Parathyroid hormone 1-34 enhances titanium implant anchorage in low-density trabecular bone: a correlative micro-computed tomographic and biomechanical analysis.Gabet, Yankel⋅Müller, Ralph⋅Levy, Jay A⋅DiMarchi, Richard D⋅Chorev, Michael⋅Bab, Itai Arye and Kohavi, DavidBone, vol. 39, (no. 2), pp. 276-82, 2006/Aug.
| Journal Article
2005
Discovery of a beta-MSH-derived MC-4R selective agonist.
Mayer, John P⋅Hsiung, Hansen M⋅Flora, David B⋅Edwards, Patrick⋅Smith, Dennis P⋅Zhang, Xing-Yue⋅Gadski, Robert A⋅Heiman, Mark L⋅Hertel, Jeanne L⋅Emmerson, Paul J⋅Husain, Saba⋅O'brien, Thomas P⋅Kahl, Steven D⋅Smiley, David L⋅Zhang, Lianshan⋅DiMarchi, Richard D and Yan, Liang Z
Journal of medicinal chemistry, vol. 48, (no. 9), pp. 3095-8, 2005/May/5. | Journal Article
Drugging the undruggable.
Mayer, John P and DiMarchi, Richard D
Chemistry & biology, vol. 12, (no. 8), pp. 860-1, 2005/Aug. | Journal Article
Drugging the Undruggable
Mayer, John P and DiMarchi, Richard D
Chemistry & Biology, vol. 12, (no. 8), pp. 861, August 2005. | Journal Article
Leptin: structure, function and biology.Zhang, Faming⋅Chen, Yanyun⋅Heiman, Mark and DiMarchi, Richard DVitamins and hormones, vol. 71, pp. 345-72, 2005.
| Journal Article
Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold
Yan, Liang Z⋅Flora, David⋅Edwards, Patrick⋅Smiley, David L⋅Emmerson, Paul J⋅Hsiung, Hansen M⋅Gadski, Robert⋅Hertel, JeAnne⋅Heiman, Mark L⋅Husain, Saba⋅O'Brien, Thomas P⋅Kahl, Steven D⋅Zhang, Lianshan⋅DiMarchi, Richard D and Mayer, John P
Bioorganic and Medicinal Chemistry Letters, vol. 15, (no. 20), pp. 4611-4614, 2005. | Journal Article
1999
Statistical and operational issues arising in an interim analysis when the study will continue
Huster, William⋅Shah, Aarti⋅Kaiser, Gary⋅Dere, Will and DiMarchi, Richard
Therapeutic Innovation & Regulatory Science, vol. 33, (no. 3), pp. 869, Jul-Sep 1999. | Journal Article
Statistical and operational issues arising in an interim analysis when the study will continue
Huster, William⋅Shah, Aarti⋅Kaiser, Gary⋅Dere, Will and DiMarchi, Richard D
Drug Information Journal, vol. 33, (no. 3), pp. 869, Jul-Sep 1999. | Journal Article
1998
Basal activity profiles of NPH and [Nepsilon-palmitoyl Lys (B29)] human insulins in subjects with IDDM.
Radziuk, J⋅Pye, S⋅Bradley, B⋅Braaten, J⋅Vignati, L⋅Roach, P⋅Bowsher, R⋅DiMarchi, Richard D and Chance, R
Diabetologia, vol. 41, (no. 1), pp. 116-20, 1998/Jan. | Journal Article
1997
Bioavailability and bioeffectiveness of subcutaneous human insulin and two of its analogs--LysB28ProB29-human insulin and AspB10LysB28ProB29-human insulin--assessed in a conscious pig model.
Radziuk, J M⋅Davies, J C⋅Pye, W S⋅Shields, J E⋅DiMarchi, Richard D and Chance, R E
Diabetes, vol. 46, (no. 4), pp. 548-56, 1997/Apr. | Journal Article
Bioavailability and bioeffectiveness of subcutaneous human insulin and two of its analogs--[Lys.sup.B28][Pro.sup.B29]-human insulin and [Asp.sup.B10][Lys.sup.B28][Pro.sup.B29]-human insulin--assessed in a conscious pig model
Davies, Jill⋅Chance, Ronald⋅Pye, W.⋅Radziuk, Jerry⋅Shields, James and DiMarchi, Richard
Diabetes, vol. 46, (no. 4), pp. 548, 19970401. | Journal Article
Crystal structure of the obese protein leptin-E100Zhang, Faming⋅Basinski, MB⋅Beals, JM⋅Briggs, SL⋅Churgay, LM⋅Clawson, DK⋅DiMarchi, Richard D⋅Furman, TC⋅Hale, JE⋅Hsiung, HM⋅Schoner, BE⋅Smith, DP⋅Zhang, Xing Y⋅Wery, J-P and Schevitz, RWNature, vol. 387, (no. 6629), pp. 206-209, 1997.
| Journal Article
Improved mealtime treatment of diabetes mellitus using an insulin analogue
Anderson, James H⋅Brunelle, Rocco L⋅Koivisto, Veikko A⋅Trautmann, Michael E⋅Vignati, Louis and DiMarchi, Richard
Clinical Therapeutics, vol. 19, (no. 1), pp. 72, 1997. | Journal Article
Improved mealtime treatment of diabetes mellitus using an insulin analogue. Multicenter Insulin Lispro Study Group.
Anderson, J H⋅Brunelle, R L⋅Koivisto, V A⋅Trautmann, M E⋅Vignati, L and DiMarchi, Richard D
Clinical therapeutics, vol. 19, (no. 1), pp. 62-72, 1997 Jan-Feb. | Journal Article
Mealtime Treatment With Insulin Analog Improves Postprandial Hyperglycemia and Hypoglycemia in Patients With Non-Insulin-Dependent Diabetes Mellitus
Anderson, James H⋅Brunelle, Rocco L⋅Keohane, Patrick⋅Koivisto, Veikko A⋅Trautmann, Michael E⋅Vignati, Louis and DiMarchi, Richard
Archives of Internal Medicine, vol. 157, (no. 11), pp. 1255, 1997-06-09. | Journal Article
Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor.
Slieker, L J⋅Brooke, G S⋅DiMarchi, Richard D⋅Flora, D B⋅Green, L K⋅Hoffmann, J A⋅Long, H B⋅Fan, L⋅Shields, J E⋅Sundell, K L⋅Surface, P L and Chance, R E
Diabetologia, vol. 40 Suppl 2, pp. S54-61, 1997/Jul. | Journal Article
New advances in insulin treatment of diabetes: overcoming barriers.
Davidson, J A⋅Garber, A J⋅DiMarchi, Richard D and Santiago, J V
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, vol. 3, (no. 6), pp. 371-84, 1997 Nov-Dec. | Journal Article
Prevention of vascular and neural dysfunction in diabetic rats by C-peptideIdo, Y.⋅Vindigni, A.⋅Chang, K.⋅Stramm, L.⋅Chance, R.⋅Heath, WF⋅DiMarchi, Richard D⋅Di Cera, Enrico and Williamson, J. RScience (Washington), vol. 277, (no. 5325), pp. 563-566, 1997.
| Journal Article
Reduction of Postprandial Hyperglycemia and Frequency of Hypoglycemia in IDDM Patients on Insulin-Analog Treatment
Anderson, James⋅Brunelle, Rocco⋅Koivisto, Veikko⋅Pfutzner, Andreas⋅Trautmann, Michael⋅Vignati, Louis and DiMarchi, Richard
Diabetes, vol. 46, (no. 2), pp. 270, 1997-02-01. | Journal Article
1994
Preparation of an insulin with improved pharmacokinetics relative to human insulin through consideration of structural homology with insulin-like growth factor I.
DiMarchi, Richard D⋅Chance, R E⋅Long, H B⋅Shields, J E and Slieker, L J
Hormone research, vol. 41 Suppl 2, pp. 93-6, 1994. | Journal Article
Stimulation of glucose uptake by insulin-like growth factor II in human muscle is not mediated by the insulin-like growth factor II/mannose 6-phosphate receptor.Burguera, B⋅Elton, C W⋅Caro, J F⋅Tapscott, E B⋅Pories, Walter J⋅DiMarchi, Richard D⋅Sakano, K and Dohm, G. LThe Biochemical journal, vol. 300 ( Pt 3), pp. 781-5, 1994/Jun/15.
| Journal Article
1992
Altering the association properties of insulin by amino acid replacement.
Brems, D N⋅Alter, L A⋅Beckage, M J⋅Chance, R E⋅DiMarchi, Richard D⋅Green, L K⋅Long, H B⋅Pekar, A H⋅Shields, J E and Frank, B H
Protein engineering, vol. 5, (no. 6), pp. 527-33, 1992/Sep. | Journal Article
Cross-reactive and serotype-specific antibodies against foot-and-mouth disease virus generated by different regions of the same synthetic peptide.
Doel, T R⋅Doel, C M⋅Staple, R F and DiMarchi, Richard D
Journal of virology, vol. 66, (no. 4), pp. 2187-94, 1992/Apr. | Journal Article
Maturation of functional antibody affinity in animals immunised with synthetic foot-and-mouth disease virus.
Mulcahy, G⋅Reid, E⋅DiMarchi, Richard D⋅Gale, C and Doel, T R
Research in veterinary science, vol. 52, (no. 2), pp. 133-40, 1992/Mar. | Journal Article