Dr. Pelus' laboratory is interested in the mechanisms that control blood cell proliferation, differentiation and migration, and how these pathways can be leveraged to define new therapies for leukemia and cancer. The primary focus of the laboratory is to understand the mechanisms that control hematopoiesis, the process by which blood cells are produced, and the disordered regulation of cell proliferation and survival characteristic of cancer cells. These studies are progressing at the molecular, cellular and animal level.
The recipient of multiple research grants, Dr. Pelus' areas of research focuses on understanding production and regulation of the stem cells that form the cellular elements of blood and how these regulatory pathways can be leveraged for therapeutic benefit.
