138 Publications (Page 3 of 6)
2003
A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases.
Yin, Juan J⋅Mohammad, Khalid S⋅Käkönen, Sanna M⋅Harris, Stephen E⋅Wu-Wong, J R⋅Wessale, Jerry L⋅Padley, Robert J⋅Garrett, Ian R⋅Chirgwin, John C and Guise, Theresa A
Proceedings of the National Academy of Sciences of the United States of America, vol. 100, (no. 19), pp. 10954-9, 2003/Sep/16. | Journal Article
 
Interactions between tumor and bone alter the phenotypes of both.
Chirgwin, John C and Guise, T A
Journal of musculoskeletal & neuronal interactions. , vol. 3, (no. 4), pp. 278-81; discussion 292-4, 2003/Dec. | Journal Article
 
Molecular mechanisms of cancer metastases to bone
Chirgwin, John M⋅Chirgwin, John M⋅Guise, Theresa A and Guise, Theresa A
Current Opinion in Orthopaedics, vol. 14, (no. 5), pp. 321, 2003-10-00. | Journal Article
 
Role of bisphosphonates in prostate cancer bone metastases.
Guise, Theresa A and Chirgwin, John C
Seminars in oncology, vol. 30, (no. 5), pp. 717-23, 2003/Oct. | Journal Article
 
The structure of human phosphoglucose isomerase complexed with a transition‐state analogue
Davies, Christopher⋅Davies, Christopher⋅Muirhead, Hilary⋅Muirhead, Hilary⋅Chirgwin, John and Chirgwin, John
Acta Crystallographica Section D, vol. 59, (no. 6), pp. 1113, June 2003. | Journal Article
 
Transforming Growth Factor-Beta in Osteolytic Breast Cancer Bone Metastases
Guise, Theresa A⋅Guise, Theresa A⋅Chirgwin, John M and Chirgwin, John M
Clinical orthopaedics and related research, vol. 415, (no. 415 Suppl), pp. S38, 2003-Oct. | Journal Article
2002
Transforming Growth Factor- beta Stimulates Parathyroid Hormone-related Protein and Osteolytic Metastases via Smad and Mitogen-activated Protein Kinase Signaling Pathways
Kaekoenen, S.⋅Selander, KS⋅Chirgwin, John C⋅Yin, JJ⋅Burns, S.⋅Rankin, WA⋅Grubbs, BG⋅Dallas, M.⋅Cui, Yan and Guise, Theresa A
Journal of Biological Chemistry, vol. 277, (no. 27), pp. 24571-24578, 2002. | Journal Article
 
Transforming Growth Factor-beta (TGF-beta) mediates breast cancer osteolysis by stimulating tumor production of PTHrP via Smad and MAP kinase pathways
Käkönen, S-M, Chirgwin JM, Selander K, Grubbs BG, Yin JJ, Guise TA and Chirgwin, John C
2002
 
Transforming Growth Factor-β Stimulates Parathyroid Hormone-related Protein and Osteolytic Metastases via Smad and Mitogen-activated Protein Kinase Signaling Pathways
Kakonen, Sanna-Maria⋅Kakonen, Sanna-Maria⋅Selander, Katri S⋅Selander, Katri S⋅Chirgwin, John M⋅Chirgwin, John M⋅Yin, Juan Juan⋅Yin, Juan Juan⋅Burns, Suzanne⋅Burns, Suzanne⋅Rankin, Wayne A⋅Rankin, Wayne A⋅Grubbs, Barry G⋅Grubbs, Barry G⋅Dallas, Mark⋅Dallas, Mark⋅Cui, Yong⋅Cui, Yong⋅Guise, Theresa A and Guise, Theresa A
The Journal of biological chemistry, vol. 277, (no. 27), pp. 24578, 2002-Jul-05. | Journal Article
2001
Molecular mechanisms of tumor: bone interactions in osteolytic metastases
Chirgwin JM, Guise TA and Chirgwin, John C
(pp. 159-178). 2001
 
The crystal structure of human phosphoglucose isomerase at 1.6 Å resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia
Read, Jon⋅Pearce, Jake⋅Li, Xiaochun⋅Muirhead, Hilary⋅Chirgwin, John and Davies, Christopher
Journal of Molecular Biology, vol. 309, (no. 2), pp. 463, 2001-06-01. | Journal Article
 
The crystal structure of human phosphoglucose isomerase at 1.6Å resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia
Read J, Pearce J, Li X, Muirhead H, Chirgwin JM, Davies C and Chirgwin, John C
(pp. 447-463). 2001
2000
Fusions to maltose-binding protein: control of folding and solubility in protein purification.
Sachdev, D and Chirgwin, J M
Methods in enzymology, vol. 326, pp. 312-321, 2000. | Journal Article
 
Fusions to maltose-binding protein to control folding and solubility
Chirgwin, John C
(pp. 312-321). 2000
 
Molecular mechanisms of tumor-bone interactions in osteolytic metastases.
Chirgwin, John C⋅Chirgwin, John M⋅Guise, T A and Guise, Theresa A
Critical reviews in eukaryotic gene expression, vol. 10, (no. 2), pp. 159-78, 2000. | Journal Article
 
Rabbit phosphoglucose isomerase/autocrine motility factor: cloning via interspecies identity
Chirgwin, John C
(pp. 363-367). 2000
 
Rabbit phosphoglucose isomerase/neuroleukin/autocrine motility factor: cloning via interspecies identity.
Li, X and Chirgwin, J M
Biochimica et biophysica acta, vol. 1476, (no. 2), pp. 363-367, February 9, 2000. | Journal Article
 
Reproductive tissue renin gene expression in preeclampsia
Shah DM, Banu JM, Chirgwin JM, Tekmal RR and Chirgwin, John C
(pp. 341-351). 2000
 
Reproductive tissue renin gene expression in preeclampsia.
Shah, D M⋅Banu, J M⋅Chirgwin, John C and Tekmal, R R
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy, vol. 19, (no. 3), pp. 341-51, 2000. | Journal Article
 
Transcriptional activation of cathepsin D gene expression by growth factors
Wang F, Duan R, Chirgwin JM, Safe SH and Chirgwin, John C
(pp. 193-202). 2000
 
Transcriptional activation of cathepsin D gene expression by growth factors.
Wang, F⋅Duan, R⋅Chirgwin, John C and Safe, Stephen H
Journal of molecular endocrinology, vol. 24, (no. 2), pp. 193-202, 2000/Apr. | Journal Article
1999
Aspartic proteinases: retroviral and cellular enzymes
Chirgwin, John C
(pp. 1762). 1999
 
Aspartic Proteinases; Retroviral and Cellular Enzymes. Advances in Experimental Biology and Medicine 436 Edited by M. N. G. James (University of Alberta). Plenum Press:  New York. 1998. $139.50. xvii + 499 pp. ISBN 0-306-45809-8
Chirgwin, John M
Journal of the American Chemical Society, vol. 121, (no. 8), pp. 1762, 19990303. | Journal Article
 
NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure and enhances interaction with GroEL under native conditions
Trevino RJ, Gliubich F, Berni R, Cianci M, Chirgwin JM, Zanotti G, Horowitz PM and Chirgwin, John C
(pp. 13938-13947). 1999
 
NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure, and enhances interaction with GroEL under native conditions.
Trevino, R J⋅Gliubich, F⋅Berni, R⋅Cianci, M⋅Chirgwin, John C⋅Zanotti, Giuseppe and Horowitz, Paul M
The Journal of biological chemistry, vol. 274, (no. 20), pp. 13938-47, 1999/May/14. | Journal Article