138 Publications (Page 2 of 6)
2009
Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
Dunn, Lauren⋅Mohammad, Khalid⋅Fournier, Pierrick⋅Davis, Holly⋅Niewolna, Maria⋅Hong, Xiang⋅Chirgwin, John and Guise, Theresa
PLoS One, vol. 4, (no. 9), Sep 2009. | Journal Article
 
The critical role of the bone microenvironment in cancer metastases
Casimiro, Sandra⋅Casimiro, Sandra⋅Guise, Theresa A⋅Guise, Theresa A⋅Chirgwin, John and Chirgwin, John
Molecular and Cellular Endocrinology, vol. 310, (no. 1), pp. 81, 2009. | Journal Article
2008
Assessing new bone formation in neonatal calvarial organ cultures.
Mohammad, Khalid S⋅Chirgwin, John C and Guise, Theresa A
Methods in molecular biology (Clifton, N.J.), vol. 455, pp. 37-50, 2008. | Journal Article
 
Intracellular Proadrenomedullin-Derived Peptides Decorate the Microtubules and Contribute to Cytoskeleton Function
Sackett, Dan L⋅Sackett, Dan L⋅Ozbun, Laurent⋅Ozbun, Laurent⋅Zudaire, Enrique⋅Zudaire, Enrique⋅Wessner, Lisa⋅Wessner, Lisa⋅Chirgwin, John M⋅Chirgwin, John M⋅Cuttitta, Frank⋅Cuttitta, Frank⋅Martínez, Alfredo and Martínez, Alfredo
Endocrinology, vol. 149, (no. 6), pp. 2898, 2008-06. | Journal Article
 
P16. Hypoxia and breast cancer bone metastasis: HIF-1α enhances TGF-β signaling and expression of prometastatic factors CXCR4 and VEGF
Kingsley, Lauren⋅Kingsley, Lauren⋅Fournier, Pierrick⋅Fournier, Pierrick⋅Chirgwin, John⋅Chirgwin, John⋅Guise, Theresa and Guise, Theresa
Cancer Treatment Reviews, vol. 34, pp. 18, 2008. | Journal Article
 
P32. Transforming growth factor-β (TGF-β) promotes prostate cancer bone metastases: Increased expression of pro-osteolytic genes and of PMEPA1, a new TGF-β signalling regulator
Fournier, Pierrick⋅Fournier, Pierrick⋅Clines, Gregory⋅Clines, Gregory⋅Chirgwin, John⋅Chirgwin, John⋅Guise, Theresa and Guise, Theresa
Cancer Treatment Reviews, vol. 34, pp. 25, 2008. | Journal Article
2007
Breaking new ground to build bone.
Kingsley, Lauren A⋅Chirgwin, John C and Guise, Theresa A
Proceedings of the National Academy of Sciences of the United States of America., vol. 104, (no. 26), pp. 10753-10754, 2007. | Journal Article
 
Dickkopf Homolog 1 Mediates Endothelin-1-Stimulated New Bone Formation
Clines, G.A.⋅Clines, Gregory⋅Mohammad, Khalid S⋅Mohammad, K.S.⋅Bao, Yongde⋅Bao, Y.⋅Stephens, O.W.⋅Stephens, Owen W⋅Suva, Larry J⋅Suva, L.J.⋅Shaughnessy, John D⋅Shaughnessy Jr., J.D.⋅Fox, Jay W⋅Fox, J.W.⋅Chirgwin, J.M.⋅Chirgwin, John C⋅Guise, T.A. and Guise, Theresa A
Molecular Endocrinology, vol. 21, (no. 2), pp. 486-498, 2007. | Journal Article
 
Molecular Biology of Bone Metastasis
Kingsley, Lauren A⋅Fournier, Pierrick G⋅Chirgwin, John C and Guise, Theresa A
Molecular Cancer Therapeutics, vol. 6, (no. 10), pp. 2609-2617, 2007. | Journal Article
 
Skeletal metastases: decreasing tumor burden by targeting the bone microenvironment.
Chirgwin, John C⋅Chirgwin, John M⋅Guise, Theresa A and Guise, Theresa A
Journal of cellular biochemistry, vol. 102, (no. 6), pp. 1333-42, 2007/Dec/15. | Journal Article
 
The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells
Bartholin, Laurent⋅Wessner, Lisa L⋅Chirgwin, John C and Guise, Theresa A
Cancer Letters, vol. 246, (no. 1-2), pp. 230-236, 2007. | Journal Article
2006
Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis.
Zudaire, Enrique⋅Zudaire, Enrique⋅Martínez, Alfredo⋅Martínez, Alfredo⋅Garayoa, Mercedes⋅Garayoa, Mercedes⋅Pío, Rubén⋅Pío, Rubén⋅Kaur, Gurmeet⋅Kaur, Gurmeet⋅Woolhiser, Michael R⋅Woolhiser, Michael R⋅Metcalfe, Dean D⋅Metcalfe, Dean D⋅Hook, William A⋅Hook, William A⋅Siraganian, Reuben P⋅Siraganian, Reuben P⋅Guise, Theresa A⋅Guise, Theresa A⋅Chirgwin, John M⋅Chirgwin, John M⋅Cuttitta, Frank and Cuttitta, Frank
The American journal of pathology, vol. 168, (no. 1), pp. 280-291, January 2006. | Journal Article
 
Basic Mechanisms Responsible for Osteolytic and Osteoblastic Bone Metastases
Guise, T.A.⋅Guise, Theresa A⋅Mohammad, Khalid S⋅Mohammad, K.S.⋅Clines, Gregory⋅Clines, G.⋅Stebbins, Elizabeth G⋅Stebbins, E.G.⋅Wong, D.H.⋅Wong, Darren H⋅Higgins, Linda S⋅Higgins, L.S.⋅Vessella, Robert⋅Vessella, R.⋅Corey, E.⋅Corey, Eva⋅Padalecki, Susan S⋅Padalecki, S.⋅Suva, Larry J⋅Suva, L.⋅Chirgwin, John C⋅Chirgwin, J.M.⋅Pearse⋅Roodman⋅Lipton⋅Clohisy⋅Weilbaecher and Smith
Clinical Cancer Research, vol. 12, (no. 20), pp. 6213s-6216s, 2006. | Journal Article
 
Does prostate-specific antigen contribute to bone metastases?
Chirgwin, John M⋅Chirgwin, John C⋅Guise, Theresa A and Guise, Theresa A
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 12, (no. 5), pp. 1395-7, 2006/Mar/1. | Journal Article
 
Meeting report from skeletal complications of malignancy IV
Vessella, Robert L⋅Vessella, Robert L⋅Guise, Theresa A⋅Guise, Theresa A⋅Susman, Edward S⋅Susman, Edward S⋅Suva, Larry J⋅Suva, Larry J⋅Clines, Gregory A⋅Clines, Gregory A⋅Kominsky, Scott L⋅Kominsky, Scott L⋅Weber, Kristy L⋅Weber, Kristy L⋅Chirgwin, John M⋅Chirgwin, John M⋅McCauley, Laurie K⋅McCauley, Laurie K⋅Kozlow, Wende and Kozlow, Wende
BoneKEy-Osteovision, vol. 3, (no. 3), pp. 42, 2006-03-00. | Journal Article
 
Molecular interactions between breast cancer cells and the bone microenvironment drive skeletal metastases
Siclari, V.A.⋅Guise, Theresa A and Chirgwin, John C
Cancer and Metastasis Reviews, vol. 25, (no. 4), pp. 621-33, Dec 2006. | Journal Article
 
New insights into the role of T cells in the vicious cycle of bone metastases
Fournier, PGJ⋅Chirgwin, John C and Guise, Theresa A
Current Opinion in Rheumatology, vol. 18, (no. 4), pp. 396-404, 2006. | Journal Article
2005
595: The Metastasis Suppressor Gene RhoGDI2 Reduceslung Metastasis in Human Bladder Cancer Via Downregulation of Endothelin 1
Titus, Brian⋅Titus, Brian⋅Chirgwin, John⋅Chirgwin, John⋅Guise, Theresa⋅Guise, Theresa⋅Hampton, Garret⋅Hampton, Garret⋅Theodorescu, Dan and Theodorescu, Dan
The Journal of Urology, vol. 173, (no. 4), pp. 163, April 2005. | Journal Article
 
Endothelin Axis Is a Target of the Lung Metastasis Suppressor Gene RhoGDI2
Titus, Brian⋅Titus, Brian⋅Titus, Brian⋅Frierson, Henry F⋅Frierson, Henry⋅Frierson, Henry⋅Conaway, Mark⋅Conaway, Mark R⋅Conaway, Mark⋅Ching, Keith⋅Ching, Keith⋅Ching, Keith⋅Guise, Theresa⋅Guise, Theresa⋅Guise, Theresa⋅Chirgwin, John⋅Chirgwin, John⋅Chirgwin, John⋅Hampton, Garret⋅Hampton, Garret⋅Hampton, Garret⋅Theodorescu, Dan⋅Theodorescu, Dan and Theodorescu, Dan
Cancer Research, vol. 65, (no. 16), pp. 7327, 20050815. | Journal Article
 
Molecular mechanisms of breast cancer metastases to bone.
Guise, Theresa A⋅Kozlow, Wende M⋅Heras-Herzig, Ailleen⋅Padalecki, Susan S⋅Yin, Juan J and Chirgwin, John M
Clinical breast cancer, vol. 5 Suppl, (no. 2), pp. S46-53, 2005/Feb. | Journal Article
 
Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway
Bendre, Manali S⋅Bendre, Manali S⋅Margulies, Aaron G⋅Margulies, Aaron G⋅Walser, Brandon⋅Walser, Brandon⋅Akel, Nisreen S⋅Akel, Nisreen S⋅Bhattacharrya, Sudeepa⋅Bhattacharrya, Sudeepa⋅Skinner, Robert A⋅Skinner, Robert A⋅Swain, Frances⋅Swain, Frances⋅Ramani, Vishnu⋅Ramani, Vishnu⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Wessner, Lisa L⋅Wessner, Lisa L⋅Martinez, Alfredo⋅Martinez, Alfredo⋅Guise, Theresa A⋅Guise, Theresa A⋅Chirgwin, John M⋅Chirgwin, John M⋅Gaddy, Dana⋅Gaddy, Dana⋅Suva, Larry J and Suva, Larry J
Cancer research, vol. 65, (no. 23), pp. 11001, 2005-Dec-01. | Journal Article
 
Tumor-Derived Interleukin-8 Stimulates Osteolysis Independent of the Receptor Activator of Nuclear Factor- Kappa B Ligand Pathway
Bendre, Manali S⋅Margulies, Aaron G⋅Walser, Brandon⋅Akel, Nisreen S⋅Bhattacharrya, Sudeepa⋅Skinner, Robert A⋅Swain, Frances⋅Ramani, Vishnu⋅Mohammad, Khalid S⋅Wessner, Lisa L⋅Martinez, Alfredo⋅Guise, Theresa A⋅Chirgwin, John C⋅Gaddy, Dana and Suva, Larry J
Cancer Research, vol. 65, (no. 23), pp. 11001-11009, 2005. | Journal Article
 
Tumor-Derived Interleukin-8 Stimulates Osteolysis Independent of the Receptor Activator of Nuclear Factor-κB Ligand Pathway
Bendre, Manali S⋅Bendre, M.S.⋅Bendre, Manali S⋅Bendre, Manali S⋅Margulies, Aaron G⋅Margulies, Aaron G⋅Margulies, A.G.⋅Margulies, Aaron G⋅Walser, Brandon⋅Walser, Brandon⋅Walser, Brandon⋅Walser, B.⋅Akel, Nisreen S⋅Akel, Nisreen S⋅Akel, Nisreen S⋅Akel, N.S.⋅Bhattacharrya, Sudeepa⋅Bhattacharrya, Sudeepa⋅Bhattacharrya, S.⋅Bhattacharrya, Sudeepa⋅Skinner, Robert A⋅Skinner, R.A.⋅Skinner, Robert A⋅Skinner, Robert A⋅Swain, F.⋅Swain, Frances⋅Swain, Frances⋅Swain, Frances⋅Ramani, Vishnu⋅Ramani, Vishnu⋅Ramani, V.⋅Ramani, Vishnu⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Mohammad, K.S.⋅Wessner, Lisa L⋅Wessner, Lisa L⋅Wessner, L.L.⋅Wessner, Lisa L⋅Martinez, Alfredo⋅Martinez, Alfredo⋅Martinez, Alfredo⋅Martinez, A.⋅Guise, Theresa A⋅Guise, Theresa A⋅Guise, T.A.⋅Guise, Theresa A⋅Chirgwin, John M⋅Chirgwin, John M⋅Chirgwin, J.M.⋅Chirgwin, John M⋅Gaddy, Dana⋅Gaddy, D.⋅Gaddy, Dana⋅Gaddy, Dana⋅Suva, L.J.⋅Suva, Larry J⋅Suva, Larry J and Suva, Larry J
Cancer Research, vol. 65, (no. 23), pp. 11009, 2005-12-01. | Journal Article
2004
The Crystal Structure of Mouse Phosphoglucose Isomerase at 1.6Å Resolution and its Complex with Glucose 6-Phosphate Reveals the Catalytic Mechanism of Sugar Ring Opening
Solomons, J T Graham⋅Zimmerly, Ella M⋅Burns, Suzanne⋅Krishnamurthy, N⋅Swan, Michael K⋅Krings, Sandra⋅Muirhead, Hilary⋅Chirgwin, John and Davies, Christopher
Journal of molecular biology, vol. 342, (no. 3), pp. 860, 2004-Sep-17. | Journal Article
 
Tumor-bone cellular interactions in skeletal metastases
Chirgwin, John C⋅Mohammad, Khalid S and Guise, Theresa A
Journal of Musculoskeletal & Neuronal Interactions, vol. 4, (no. 3), pp. 308-318, 2004. | Journal Article