157 Publications (Page 6 of 7)
2002
Regulation of Internal Ribosome Entry Site-mediated Translation by Eukaryotic Initiation Factor-2α Phosphorylation and Translation of a Small Upstream Open Reading Frame
Fernandez, James⋅Yaman, Ibrahim⋅Merrick, William C⋅Koromilas, Antonis⋅Wek, Ronald C⋅Sood, Rushira⋅Hensold, Jack and Hatzoglou, Maria
Journal of Biological Chemistry, vol. 277, (no. 3), pp. 2058, 2002-01-18. | Journal Article
 
The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.
Zhang, Peichuan⋅McGrath, Barbara C⋅Reinert, Jamie⋅Olsen, DeAnne S⋅Lei, Li⋅Gill, Sangeeta⋅Wek, Sheree A⋅Vattem, Krishna M⋅Wek, Ronald C⋅Kimball, Scot R⋅Jefferson, Leonard S and Cavener, Douglas R
Molecular and cellular biology, vol. 22, (no. 19), pp. 6681-8, 2002/Oct. | Journal Article
 
The GCN2 eIF2[alpha] Kinase Is Required for Adaptation to Amino Acid Deprivation in Mice
Zhang, P.⋅McGrath, BC⋅Reinert, J.⋅Olsen, DS⋅Lei, L.⋅Gill, S.⋅Wek, SA⋅Vattem, KM⋅Wek, Ronald⋅Kimball, Scot R⋅Jefferson, Leonard S and Cavener, Douglas R
Molecular and Cellular Biology, vol. 22, (no. 19), pp. 6681-6688, 2002. | Journal Article
2001
Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2α (eIF2α)
Vattem, Krishna M⋅Vattem, Krishna M⋅Staschke, Kirk A⋅Staschke, Kirk A⋅Zhu, Shuhao⋅Zhu, Shuhao⋅Wek, Ronald C and Wek, Ronald C
European Journal of Biochemistry, vol. 268, (no. 4), pp. 1153, 2001-02-00. | Journal Article
 
Mechanism of activation of the double‐stranded‐RNA‐dependent protein kinase, PKR
Vattem, Krishna M⋅Vattem, K.M.⋅Staschke, Kirk A⋅Staschke, K.A.⋅Wek, R.C. and Wek, Ronald C
European Journal of Biochemistry, vol. 268, (no. 13), pp. 3684, July 2001. | Journal Article
 
Mechanism of activation of the double-stranded-RNA-dependent protein kinase, PKR: role of dimerization and cellular localization in the stimulation of PKR phosphorylation of eukaryotic initiation factor-2 (eIF2).
Vattem, K M⋅Staschke, K A and Wek, Ronald C
European journal of biochemistry / FEBS, vol. 268, (no. 13), pp. 3674-84, 2001/Jul. | Journal Article
 
The Double-Stranded RNA-Activated Protein Kinase PKR Is Dispensable for Regulation of Translation Initiation in Response to either Calcium Mobilization from the Endoplasmic Reticulum or Essential Amino Acid Starvation
Kimball, Scot R⋅Clemens, MJ⋅Tilleray, VJ⋅Wek, Ronald⋅Horetsky, RL and Jefferson, Leonard S
Biochemical and Biophysical Research Communications, vol. 280, (no. 1), pp. 293-300, 2001. | Journal Article
2000
A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2 alpha
Sood, R.⋅Porter, AC⋅Olsen, D.⋅Cavener, Douglas R and Wek, Ronald
Genetics, vol. 154, (no. 2), pp. 787-801, 2000. | Journal Article
 
A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha.
Sood, R⋅Porter, A C⋅Olsen, D A⋅Cavener, Douglas R and Wek, Ronald C
Genetics, vol. 154, (no. 2), pp. 787-801, 2000/Feb. | Journal Article
 
Glucose Limitation Induces GCN4 Translation by Activation of Gcn2 Protein Kinase
Yang, R.⋅Wek, SA and Wek, Ronald
Molecular and Cellular Biology, vol. 20, (no. 8), pp. 2706-2717, 2000. | Journal Article
 
Pancreatic eukaryotic initiation factor-2 alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress
Sood, R.⋅SOOD, Ruchira⋅Porter, AC⋅PORTER, Amy C⋅MA, Kun⋅Ma, K.⋅Quilliam, Lawrence A⋅Quilliam, LA⋅WEK, Ronald C and Wek, Ronald
Biochemical Journal, vol. 346, (no. 2), pp. 281-293, 2000. | Journal Article
 
Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells
Harding, Heather P⋅Novoa, I.⋅Zhang, Yuhong⋅Zeng, Huiqing⋅Wek, Ronald⋅Schapira, M. and Ron, David
Molecular Cell, vol. 6, (no. 5), pp. 1099-1108, 2000. | Journal Article
1998
Identification and Characterization of Pancreatic Eukaryotic Initiation Factor 2 α-Subunit Kinase, PEK, Involved in Translational Control
Shi, Yuguang⋅Vattem, Krishna⋅Sood, Ruchira⋅An, Jie⋅Liang, Jingdong⋅Stramm, Lawrence and Wek, Ronald
Molecular and Cellular Biology, vol. 18, (no. 12), pp. 7509, 19981201. | Journal Article
 
Isolation of the gene encoding the Drosophila melanogaster homolog of the Saccharomyces cerevisiae GCN2 eIF-2alpha kinase.
Olsen, D S⋅Jordan, B⋅Chen, D⋅Wek, Ronald C and Cavener, Douglas R
Genetics, vol. 149, (no. 3), pp. 1495-509, 1998/Jul. | Journal Article
 
Isolation of the Gene Encoding the Drosophila melanogaster Homolog of the Saccharomyces cerevisiae GCN2 eIF-2{alpha} Kinase
Olsen, DeAnne⋅Jordan, Barbara⋅Chen, Dreeny⋅Wek, Ronald and Cavener, Douglas
Genetics, vol. 149, (no. 3), pp. 1495, 19980701. | Journal Article
 
Isolation of the gene encoding the Drosophila melanogaster homolog of th Saccharomyces cerevisiae GCN2 eIF-2alpha kinase
Olsen, DeAnne S⋅Jordan, Barbara⋅Chen, Dreeny⋅Wek, Ronald and Cavener, Douglas R
Genetics, vol. 149, (no. 3), pp. 1495-1509, Jul 1998. | Journal Article
 
Mitochondrial Respiratory Mutants in Yeast Inhibit Glycogen Accumulation by Blocking Activation of Glycogen Synthase
Yang, Ruojing⋅Chun, Kristin and Wek, Ronald
Journal of Biological Chemistry, vol. 273, (no. 47), pp. 31344, 19981120. | Journal Article
 
Ribosome-binding Domain of Eukaryotic Initiation Factor-2 Kinase GCN2 Facilitates Translation Control
Zhu, Shuhao and Wek, Ronald
Journal of Biological Chemistry, vol. 273, (no. 3), pp. 1814, 19980116. | Journal Article
1997
Ribosome Targeting of PKR Is Mediated by Two Double-stranded RNA-binding Domains and Facilitates in Vivo Phosphorylation of Eukaryotic Initiation Factor-2
Zhu, Shuhao⋅Romano, Patrick and Wek, Ronald
Journal of Biological Chemistry, vol. 272, (no. 22), pp. 14434, 19970530. | Journal Article
1996
Expression of Vaccinia Virus K3L Protein in Yeast Inhibits Eukaryotic Initiation Factor-2 Kinase GCN2 and the General Amino Acid Control Pathway
Qian, Weijun⋅Zhu, Shuhao⋅Sobolev, Alexander and Wek, Ronald
Journal of Biological Chemistry, vol. 271, (no. 22), pp. 13207, 19960531. | Journal Article
 
Histidyl-tRNA synthetase-related sequences in GCN2 protein kinase regulate in vitro phosphorylation of eIF-2
Zhu, Shuhao⋅Sobolev, AY and Wek, Ronald
Journal of Biological Chemistry, vol. 271, (no. 40), pp. 24989-24994, 1996. | Journal Article
1994
eIF-2 kinases: regulators of general and gene-specific translation initiation.
Wek, Ronald C
Trends in biochemical sciences, vol. 19, (no. 11), pp. 491-6, 1994/Nov. | Journal Article
 
elF-2 kinases: regulators of general and gene-specific translation initiation
Wek, Ronald C
Trends in Biochemical Sciences, vol. 19, (no. 11), pp. 496, 1994. | Journal Article
1992
Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast.
Dever, T E⋅Feng, L⋅Wek, Ronald C⋅Cigan, A M⋅Donahue, Thomas F and Hinnebusch, Alan G
Cell, vol. 68, (no. 3), pp. 585-96, 1992/Feb/7. | Journal Article
 
Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast
Dever, Thomas E⋅Feng, Lan⋅Wek, Ronald C⋅Cigan, A.Mark⋅Donahue, Thomas F and Hinnebusch, Alan G
Cell, vol. 68, (no. 3), pp. 596, 1992-02-07. | Journal Article