21 Publications
2022
Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake
McMillin, Shawna L⋅Evans, Parker L⋅Taylor, William M⋅Weyrauch, Luke A⋅Sermersheim, Tyler J⋅Welc, Steven S⋅Heitmeier, Monique R⋅Hresko, Richard C⋅Hruz, Paul W⋅Koumanov, Francoise⋅Holman, Geoffrey D⋅Abel, E D⋅Abel, E D⋅Witczak, Carol A and Witczak, Carol A
Biomolecules, vol. 12, (no. 12), 2022. | Journal Article
 
Myeloid cell‐specific mutation of Spi1 selectively reduces M2 ‐biased macrophage numbers in skeletal muscle, reduces age‐related muscle fibrosis and prevents sarcopenia. Aging Cell
2021
Myeloid cell-mediated targeting of LIF to dystrophic muscle causes transient increases in muscle fiber lesions by disrupting the recruitment and dispersion of macrophages in muscle. Human molecular genetics
2020
Differential Effects of Myeloid Cell PPAR\updelta and IL-10 in Regulating Macrophage Recruitment, Phenotype, and Regeneration following Acute Muscle Injury
Welc, Steven S.⋅Wehling-Henricks, Michelle⋅Antoun, Jacqueline⋅Ha, Tracey T.⋅Tous, Isabella and Tidball, James G.
The Journal of Immunology, pp. ji2000247. | Journal Article
 
Modulation of Klotho expression in injured muscle perturbs Wnt signalling and influences the rate of muscle growth
Welc, Steven S⋅Wehling‐Henricks, Michelle⋅Kuro‐o, Makoto⋅Thomas, Kyle A and Tidball, James G
Experimental Physiology, vol. 105, (no. 1), pp. 147, 1 January 2020. | Journal Article
2019
Aging of the immune system causes reductions in muscle stem cell populations, promotes their shift to a fibrogenic phenotype, and modulates sarcopenia
Wang, Ying⋅Wang, Ying⋅Wehling-Henricks, Michelle⋅Wehling-Henricks, Michelle⋅Welc, Steven S⋅Welc, Steven S⋅Fisher, Allison L⋅Fisher, Allison L⋅Zuo, Qun⋅Zuo, Qun⋅Tidball, James G and Tidball, James G
The FASEB Journal, vol. 33, (no. 1), pp. 1427, January 2019. | Journal Article
 
Modulation of Klotho expression in injured muscle perturbs Wnt signalling and influences the rate of muscle growth.
Experimental physiology. | Journal Article
 
Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
Welc, Steven S⋅Flores, Ivan⋅Wehling-Henricks, Michelle⋅Ramos, Julian⋅Wang, Ying⋅Bertoni, Carmen and Tidball, James G
Nature communications, vol. 10, (no. 1), pp. 17, 2019-06-26. | Journal Article
2018
Immunobiology of Inherited Muscular Dystrophies
Tidball, James G⋅Tidball, James G⋅Welc, Steven S⋅Welc, Steven S⋅Wehling-Henricks, Michelle and Wehling-Henricks, Michelle
Comprehensive Physiology, vol. 8, (no. 4), pp. 1356, 2018-09-14. | Journal Article
 
Macrophages escape Klotho gene silencing in the mdx mouse model of Duchenne muscular dystrophy and promote muscle growth and increase satellite cell numbers through a Klotho-mediated pathway
Wehling-Henricks, Michelle⋅Welc, Steven S⋅Samengo, Guiseppina⋅Rinaldi, Chiara⋅Lindsey, Catherine⋅Wang, Ying⋅Lee, Jeongyoon⋅Kuro-O, Makoto and Tidball, James G
Human Molecular Genetics, vol. 27, (no. 1), pp. 29, 20180101. | Journal Article
 
Myeloid cell‐derived tumor necrosis factor‐alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers
Wang, Ying⋅Wang, Ying⋅Welc, Steven S⋅Welc, Steven S⋅Wehling‐Henricks, Michelle⋅Wehling-Henricks, Michelle⋅Tidball, James G and Tidball, James G
Aging Cell, vol. 17, (no. 6), pp. n/a, December 2018. | Journal Article
2016
Klotho gene silencing promotes pathology in the mdx mouse model of Duchenne muscular dystrophy
Wehling-Henricks, Michelle⋅Wehling-Henricks, Michelle⋅Li, Zhenzhi⋅Li, Zhenzhi⋅Lindsey, Catherine⋅Lindsey, Catherine⋅Wang, Ying⋅Wang, Ying⋅Welc, Steven S⋅Welc, Steven S⋅Ramos, Julian N⋅Ramos, Julian N⋅Khanlou, Négar⋅Khanlou, Négar⋅Kuro-O, Makoto⋅Kuro-O, Makoto⋅Tidball, James G and Tidball, James G
Human molecular genetics, vol. 25, (no. 12), pp. 2482, 2016-06-15. | Journal Article
 
Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy
Chadwick, Jessica A⋅Chadwick, Jessica A⋅Swager, Sarah A⋅Swager, Sarah A⋅Lowe, Jeovanna⋅Lowe, Jeovanna⋅Welc, Steven S⋅Welc, Steven S⋅Tidball, James G⋅Tidball, James G⋅Gomez-Sanchez, Celso E⋅Gomez-Sanchez, Celso E⋅Gomez-Sanchez, Elise P⋅Gomez-Sanchez, Elise P⋅Rafael-Fortney, Jill A and Rafael-Fortney, Jill A
Human molecular genetics, vol. 25, (no. 23), pp. 5177, 2016-12-01. | Journal Article
 
The Impact of Hyperthermia on Receptor-Mediated Interleukin-6 Regulation in Mouse Skeletal Muscle
Welc, Steven S⋅Welc, Steven S⋅Morse, Deborah A⋅Morse, Deborah A⋅Mattingly, Alex J⋅Mattingly, Alex J⋅Laitano, Orlando⋅Laitano, Orlando⋅King, Michelle A⋅King, Michelle A⋅Clanton, Thomas L and Clanton, Thomas L
PloS one, vol. 11, (no. 2), pp. e0148927, 2016-00-00. | Journal Article
2015
Macrophage-Derived IGF-1 Is a Potent Coordinator of Myogenesis and Inflammation in Regenerating Muscle
Tidball, James G⋅Tidball, James G⋅Welc, Steven S and Welc, Steven S
Molecular Therapy, vol. 23, (no. 7), pp. 1135, July 2015. | Journal Article
 
Protection of intestinal injury during heat stroke in mice by interleukin‐6 pretreatment
Phillips, Neil A⋅Phillips, Neil A⋅Welc, Steven S⋅Welc, Steven S⋅Wallet, Shannon M⋅Wallet, Shannon M⋅King, Michelle A⋅King, Michelle A⋅Clanton, Thomas L and Clanton, Thomas L
The Journal of Physiology, vol. 593, (no. 3), pp. 753, 1 February 2015. | Journal Article
2013
Heat stroke activates a stress-induced cytokine response in skeletal muscle
Welc, Steven⋅Welc, Steven S⋅Clanton, Thomas L⋅Clanton, Thomas⋅Dineen, Shauna M⋅Dineen, Shauna⋅Leon, Lisa and Leon, Lisa R
Journal of Applied Physiology, vol. 115, (no. 8), pp. 1137, 2013-10-15. | Journal Article
 
Skeletal muscle interleukin-6 regulation in hyperthermia
Welc, Steven S⋅Welc, Steven⋅Judge, Andy⋅Judge, Andrew⋅Clanton, Thomas and Clanton, Thomas
American Journal of Physiology - Cell Physiology, vol. 305, (no. 4), pp. 413, 2013-08-15. | Journal Article
 
The regulation of interleukin‐6 implicates skeletal muscle as an integrative stress sensor and endocrine organ
Welc, Steven S⋅Welc, Steven S⋅Clanton, Thomas L and Clanton, Thomas L
Experimental Physiology, vol. 98, (no. 2), pp. 371, February 2013. | Journal Article
2012
Hyperthermia increases interleukin-6 in mouse skeletal muscle
Welc, Steven⋅Welc, Steven S⋅Phillips, Neil⋅Phillips, Neil A⋅Oca-Cossio, Jose⋅Oca-Cossio, Jose⋅Wallet, Shannon⋅Wallet, Shannon M⋅Chen, Daniel L⋅Chen, Daniel⋅Clanton, Thomas and Clanton, Thomas L
American Journal of Physiology - Cell Physiology, vol. 303, (no. 4), pp. 466, 2012-08-15. | Journal Article
2010
Heat Stroke Up Regulates Interleukin-6 In Skeletal Muscle
Welc, Steven S⋅Oca-Cossio, Jose⋅Novosad, Veronica L⋅Phillips, Neil A and Clanton, Thomas L
Medicine & Science in Sports & Exercise, vol. 42, pp. 31, 2010-10-00. | Journal Article