Expertise

Her laboratory focuses on the contributions that the vasculature brings to functional lung development such as alveolar formation. In addition, her studies explore the role of sphingolipids in regulating tissue regeneration in disease process such as lung disease of prematurity.

In other studies she also explores cancer progression in collaboration with Dr. Roderich Schwarz’s lab where they seek new conventions in pancreatic cancer tumor control.

Our main interests are the role that the anti-angiogenic mediator Endothelial Monocyte Activating Polypeptide II (EMAP II, also known as AIMP-1, Scye-1, and p43) has in lung and tumor development.

Research:

  • Vascular mediation of tissue development, repair, and tumor growth

Primary Research Areas:

  • Biochemistry

Research Specialties:

  • Life Processes
  • Medicine

Currently, our studies focus on the mechanisms that modulate pulmonary vascular growth and the subsequent impact that the vasculature has on alveolar growth by examining vessel mediation of interstitial lung disease, deposition of the extracellular matrix protein, and epithelial cell proliferation.

Affiliations

Professor, IUSM South Bend, Indiana University School of Medicine

Professor, Department of Pediatrics, Indiana University School of Medicine

Professor, Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine

Harper Cancer Research Institute, Notre Dame Research, University of Notre Dame

Adjunct Professor, Department of Chemistry and Biochemistry, College of Science, University of Notre Dame
2014

Past Affiliations

Associate Professor, Integrative Biology Graduate Program, Southwestern Graduate School of Biomedical Sciences, University of Texas Southwestern Medical Center at Dallas (past)

Associate Professor, Critical Care Division, Department of Pediatrics, Medical School, University of Texas Southwestern Medical Center at Dallas (past)

Associate Professor, Pediatric Pulmonary and Vascular Biology, Department of Pediatrics, Medical School, University of Texas Southwestern Medical Center at Dallas (past)

Communities
Pediatrics, Human Anatomy, Cell Biology
Degrees
MD, University of Missouri-Kansas City, Medicine, 1987
BA, University of Missouri-Kansas City, Biology, 1986