221 Publications (Page 2 of 9)
2019
SUN-LB064 A Phase 2, Dose-Escalation, Safety and Efficacy Study of Tildacerfont (SPR001) for the Treatment of Patients with Classic Congenital Adrenal Hyperplasia
Sarafoglou, KyriakieNewfield, RonVogiatzi, MariaImel, ErikOdugbesan, AMadu, Ivy-JoanNakhle, SamerHowerton, AlexisHuang, MichaelVandever, KellyLin, RongWu-Zhang, Alyssa and Auchus, Richard
Journal of the Endocrine Society, vol. 3, (no. Supplement_1), 2019-04-15. | Journal Article
 
Sustained efficacy and safety of burosumab, a fully human anti-FGF23 monoclonal antibody, in children and early adolescents with X-linked hypophosphatemia
Hogler, WolfgangCarpenter, ThomasImel, ErikPortale, AnthonyBoot, AnnemiekeLinglart, AgnesPadidela, RajaHoff, William van'tMao, MengSkrinar, AlisonMartin, Javier San and Whyte, Michael
Bone Abstracts, 2019-07-31. | Journal Article
 
The Lifelong Impact of X-Linked Hypophosphatemia: Results From a Burden of Disease Survey
Skrinar, AlisonDvorak-Ewell, MelitaEvins, AylaMacica, CarolynLinglart, AgnèsImel, Erik ATheodore-Oklota, Christina and San Martin, Javier
Journal of the Endocrine Society, vol. 3, (no. 7), pp. 1334, 2019-Jul-01. | Journal Article
2018
A PHASE 3 RANDOMIZED, PLACEBO-CONTROLLED STUDY INVESTIGATING BUROSUMAB FOR ADULT X-LINKED HYPOPHOSPHATEMIA (XLH)
Beur, SuzanneCarpenter, ThomasBriot, KarineImel, ErikKamenický, PeterRuppe, MaryPortale, AnthonyWeber, ThomasPitukcheewanont, PisitCheong, HaeImanishi, YasuoIto, NobuakiLachmann, RobinTanaka, HiroyukiZhang, LinTheodore-Oklota, ChristinaMealiffe, MattMartin, Javier and Insogna, Karl
Endocrine Practice, vol. 24, pp. 112, 20180401. | Journal Article
 
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial Evaluating the Efficacy of Burosumab, an Anti-FGF23 Antibody, in Adults With X-Linked Hypophosphatemia: Week 24 Primary Analysis.
Insogna, Karl LBriot, KarineImel, Erik AKamenický, PeterRuppe, Mary DPortale, Anthony AWeber, ThomasPitukcheewanont, PisitCheong, Hae IlJan de Beur, SuzanneImanishi, YasuoIto, NobuakiLachmann, Robin HTanaka, HiroyukiPerwad, FarzanaZhang, LinChen, Chao-YinTheodore-Oklota, ChristinaMealiffe, MattSan Martin, Javier and Carpenter, Thomas O
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, June 26, 2018. | Journal Article
 
BUROSUMAB FOR X-LINKED HYPOPHOSPHATEMIA (XLH): RESULTS FROM TWO PEDIATRIC PHASE 2 TRIALS
Portale, AnthonyImel, ErikWhyte, MichaelBoot, AnnemiekeHögler, WolfgangLinglart, AgnèsPadidela, RajaHoff, WilliamGottesman, GaryMao, MengSkrinar, AlisonMartin, Javier and Carpenter, Thomas
Endocrine Practice, vol. 24, pp. 120, 20180401. | Journal Article
 
Burosumab Improved Rickets, Phosphate Metabolism, and Clinical Outcomes Compared to Conventional Therapy in Children with X-Linked Hypophosphatemia (XLH) - A Randomized Controlled Phase 3 Study
Nilsson, OlaWhyte, Michael PImel, Erik AMunns, CraigPortale, Anthony AWard, LeanneSimmons, Jill HPadidela, RajaNamba, NoriyukiCheong, Hae IlMao, MengSkrinar, AlisonChen, Chao-YinMartin, Javier San and Glorieux, Francis
Hormone Research in Paediatrics, vol. 90, (no. Suppl.1), pp. 57, 2018. | Journal Article
 
Burosumab Therapy in Children with X-Linked Hypophosphatemia.
Carpenter, Thomas OWhyte, Michael PImel, Erik ABoot, Annemieke MHögler, WolfgangLinglart, AgnèsPadidela, RajaVan't Hoff, Williamvan't Hoff, WilliamMao, MengChen, Chao-YinSkrinar, AlisonKakkis, EmilSan Martin, Javier and Portale, Anthony A
The New England journal of medicine, vol. 378, (no. 21), pp. 1987-1998, May 24, 2018. | Journal Article
 
Genetic Variants Associated with Circulating Fibroblast Growth Factor 23
C, Robinson-CohenRobinson-Cohen, CassianneRobinson-Cohen, CassianneRobinson-Cohen, CassianneRobinson-Cohen, CassianneRobinson Cohen, CassianneTM, BartzBartz, Traci MBartz, Traci MBartz, Traci MBartz, Traci M.Bartz, Traci MLai, DongbingD, LaiLai, DongbingLai, DongbingLai, DongbingLai, DongbingAlp Ikizler, T.Ikizler, T AlpIkizler, T AlpIkizler, T AlpTA, IkizlerIkizler, T AlpM, PeacockPeacock, MunroPeacock, MunroPeacock, MunroPeacock, MunroPeacock, MunroImel, Erik AEA, ImelImel, Erik AImel, Erik AImel, Erik AImel, Erik A.Michos, Erin DMichos, Erin DMichos, Erin D.Michos, Erin DED, MichosMichos, Erin DForoud, Tatiana MForoud, Tatiana MForoud, Tatiana MForoud, Tatiana M.Foroud, Tatiana MTM, ForoudAkesson, KristinaK, AkessonAkesson, KristinaAkesson, KristinaAkesson, KristinaAkesson, KristinaTaylor, Kent DTaylor, Kent DTaylor, Kent DTaylor, Kent DKD, TaylorTaylor, Kent D.Malmgren, LinneaMalmgren, LinneaL, MalmgrenMalmgren, LinneaMalmgren, LinneaMalmgren, LinneaMatsushita, KunihiroK, MatsushitaMatsushita, KunihiroMatsushita, KunihiroMatsushita, KunihiroMatsushita, KunihiroNethander, MariaNethander, MariaNethander, MariaNethander, MariaNethander, MariaM, NethanderEriksson, JoelEriksson, JoelEriksson, JoelEriksson, JoelEriksson, JoelBR, KestenbaumOhlsson, ClaesOhlsson, ClaesOhlsson, ClaesOhlsson, ClaesOhlsson, ClaesMellström, DanielMellström, DanielMellström, DanielMellström, DanielMellström, DanielWolf, MylesWolf, MylesWolf, MylesWolf, MylesWolf, MylesLjunggren, OstenLjunggren, OstenLjunggren, OstenLjunggren, OstenLjunggren, OstenMcGuigan, FionaMcGuigan, FionaMcGuigan, FionaMcGuigan, FionaMcGuigan, FionaRotter, Jerome IRotter, Jerome I.Rotter, Jerome IRotter, Jerome IRotter, Jerome IKarlsson, MagnusKarlsson, MagnusKarlsson, MagnusKarlsson, MagnusKarlsson, MagnusEcons, Michael JEcons, Michael JEcons, Michael JEcons, Michael J.Econs, Michael JIx, Joachim HIx, Joachim H.Ix, Joachim HIx, Joachim HIx, Joachim HLutsey, Pamela LLutsey, Pamela LLutsey, Pamela L.Lutsey, Pamela LLutsey, Pamela LPsaty, Bruce MPsaty, Bruce MPsaty, Bruce MPsaty, Bruce MPsaty, Bruce M.De Boer, Ian H.de Boer, Ian Hde Boer, Ian Hde Boer, Ian Hde Boer, Ian HKestenbaum, Bryan RKestenbaum, Bryan R.Kestenbaum, Bryan RKestenbaum, Bryan R and Kestenbaum, Bryan R
Journal of the American Society of Nephrology : JASN, vol. 29, (no. 10), pp. 2592, 2018-10-00. | Journal Article
 
Osteogenesis Imperfecta Type I: Recognition in Primary Care
Tatlock, Rexanna LTatlock, Rexanna L.Edwards, NancyEdwards, NancyImel, Erik A.Imel, Erik AFoli, Karen J and Foli, Karen J.
The Journal for Nurse Practitioners, vol. 14, (no. 6), pp. 476, June 2018. | Journal Article
 
Prevalence of Nephrocalcinosis in Pseudohypoparathyroidism: Is Screening Necessary?
Hansen, David WHansen, David WHansen, David WMaahs, David MHansen, David WNebesio, Todd DNebesio, Todd DNebesio, Todd DNebesio, Todd DDi Meglio, Linda ADiMeglio, Linda ADiMeglio, Linda ADiMeglio, Linda AEugster, Erica AEugster, Erica AEugster, Erica AEugster, Erica AImel, Erik AImel, Erik AImel, Erik A and Imel, Erik A
The Journal of Pediatrics, vol. 199, pp. 266, August 2018. | Journal Article
2017
A randomized, open-label Phase 2 study of KRN23, an investigational fully human Anti-FGF23 monoclonal antibody, in children with X-linked Hypophosphatemia (XLH)
Hogler, WolfgangPortale, AnthonyImel, ErikBoot, AnnemiekeLinglart, AgnesPadidela, Rajavan't, Hoff WilliamWhyte, MichaelMao, MengSkrinar, AlisonMartin, Javier San and Carpenter, Thomas
Bone Abstracts, 2017-07-11. | Journal Article
 
Effects of KRN23, a fully human anti-FGF23 monoclonal antibody, on functional outcomes in children with X-linked hypophosphatemia (XLH): results from a randomized, open-label Phase 2 study
Imel, ErikCarpenter, ThomasLinglart, AgnesBoot, AnnemiekeHogler, WolfgangPadidela, Rajavan't, Hoff WilliamPortale, AnthonyMao, MengSkrinar, AlisonSan, Martin Javier and Whyte, Michael P
Bone Abstracts, 2017-07-11. | Journal Article
 
Infants With Congenital Adrenal Hyperplasia Are at Risk for Hypercalcemia, Hypercalciuria, and Nephrocalcinosis
Schoelwer, Melissa JSchoelwer, Melissa JSchoelwer, Melissa JViswanathan, VidhyaViswanathan, VidhyaViswanathan, VidhyaWilson, AmyWilson, AmyWilson, AmyNailescu, CorinaNailescu, CorinaNailescu, CorinaImel, Erik AImel, Erik A and Imel, Erik A
Journal of the Endocrine Society, vol. 1, (no. 9), pp. 1167, 2017-Sep-01. | Journal Article
 
KRN23 effects on phosphate and vitamin D dysregulation in children <5 years old with X-Linked Hypophosphatemia (XLH)
Imel, ErikCarpenter, ThomasGottesman, Gary SMartin, Javier SanMao, MengSkrinar, Alison and Whyte, Michael P
Bone Abstracts, 2017-07-11. | Journal Article
 
Unexpected widespread hypophosphatemia and bone disease associated with elemental formula use in infants and children
Gonzalez Ballesteros, Luisa FGonzalez Ballesteros, Luisa FMa, Nina SMa, Nina SGordon, Rebecca JGordon, Rebecca JWard, LeanneWard, LeanneBackeljauw, PhilippeBackeljauw, PhilippeWasserman, HalleyWasserman, HalleyWeber, David RWeber, David RDi Meglio, Linda ADiMeglio, Linda AGagne, JulieGagne, JulieStein, RobertStein, RobertCody, DeclanCody, DeclanSimmons, KimberSimmons, KimberZimakas, PaulZimakas, PaulTopor, Lisa SwartzTopor, Lisa SwartzAgrawal, SungeetaAgrawal, SungeetaCalabria, AndrewCalabria, AndrewTebben, PeterTebben, PeterFaircloth, RuthFaircloth, RuthImel, Erik AImel, Erik ACasey, LindaCasey, LindaCarpenter, Thomas O and Carpenter, Thomas O
Bone, vol. 97, pp. 292, April 2017. | Journal Article
2016
Disparities in osteoporosis treatments
Liu, ZWeaver, Jde Papp, ALi, ZMartin, JAllen, KHui, S and Imel, E
Osteoporosis International, vol. 27, (no. 2), pp. 509-519, Feb 2016. | Journal Article
 
Effect of four monthly doses of a human monoclonal anti-FGF23 antibody (KRN23) on quality of life in X-linked hypophosphatemia.
Ruppe, Mary DZhang, XiaopingImel, Erik AWeber, Thomas JKlausner, Mark AIto, TakahiroVergeire, MariaHumphrey, Jeffrey SGlorieux, Francis HPortale, Anthony AInsogna, KarlPeacock, Munro and Carpenter, Thomas O
Bone reports, vol. 5, pp. 158-162, December 2016. | Journal Article
 
Effect of KRN23, a fully human anti-FGF23 monoclonal antibody, on rickets in children with X-linked hypophosphatemia (XLH): 40-week interim results from a randomized, open-label phase 2 study
Padidela, Rajavan't, Hoff WilliamHogler, WolfgangPortale, AnthonyImel, ErikBoot, AnnemiekeLinglart, AgnesWhyte, MichaelSkrinar, AlisonSan, Martin Javier and Carpenter, Thomas
Endocrine Abstracts, 2016-11-14. | Journal Article
 
Genome-wide association study of serum iron phenotypes in premenopausal women of European descent.
Koller, Daniel LKoller, Daniel LImel, Erik AImel, Erik ALai, DongbingLai, DongbingPadgett, Leah RPadgett, Leah RActon, DenaActon, DenaGray, AmieGray, AmiePeacock, MunroPeacock, MunroEcons, Michael JEcons, Michael JForoud, Tatiana and Foroud, Tatiana
Blood cells, molecules & diseases, vol. 57, pp. 50-53, March 2016. | Journal Article
 
Pharmacokinetics and pharmacodynamics of a human monoclonal anti-FGF23 antibody (KRN23) in the first multiple ascending-dose trial treating adults with X-linked hypophosphatemia.
Zhang, XiaopingImel, Erik ARuppe, Mary DWeber, Thomas JKlausner, Mark AIto, TakahiroVergeire, MariaHumphrey, JeffreyGlorieux, Francis HPortale, Anthony AInsogna, KarlCarpenter, Thomas O and Peacock, Munro
Journal of clinical pharmacology, vol. 56, (no. 2), pp. 176-185, February 2016. | Journal Article
 
Population pharmacokinetic and pharmacodynamic analyses from a 4-month intradose escalation and its subsequent 12-month dose titration studies for a human monoclonal anti-FGF23 antibody (KRN23) in adults with X-linked hypophosphatemia.
Zhang, XiaopingPeyret, ThomasGosselin, Nathalie HMarier, J FImel, Erik A and Carpenter, Thomas O
Journal of clinical pharmacology, vol. 56, (no. 4), pp. 429-438, April 2016. | Journal Article
 
Proportion of osteoporotic women remaining at risk for fracture despite adherence to oral bisphosphonates.
Imel, ErikImel, Erik AImel, ErikEckert, GeorgeEckert, GeorgeEckert, GeorgeModi, AnkitaModi, AnkitaModi, AnkitaLi, ZhuokaiLi, ZhuokaiLi, ZhuokaiMartin, JoelMartin, JoelMartin, Joelde Papp, AnnePapp, AnnePapp, AnneAllen, KatieAllen, KatieAllen, KatieJohnston, C.Johnston, C ConradJohnston, C.Hui, Siu LHui, SiuHui, SiuLiu, ZiyueLiu, Ziyue and Liu, Ziyue
Bone, vol. 83, pp. 267-275, February 2016. | Journal Article
 
Serum fibroblast growth factor 23, serum iron and bone mineral density in premenopausal women.
Imel, Erik ALiu, ZiyueMcQueen, Amie KActon, DenaActon, AnthonyPadgett, Leah RPeacock, Munro and Econs, Michael J
Bone, vol. 86, pp. 98-105, May 2016. | Journal Article
2015
A Clinician's Guide to X‐Linked Hypophosphatemia
Carpenter, Thomas OImel, Erik AHolm, Ingrid AJan de Beur, Suzanne M and Insogna, Karl L
Journal of Bone and Mineral Research, vol. 30, (no. 2), pp. 394, February 2015. | Journal Article