221 Publications (Page 2 of 9)
2019
SUN-LB064 A Phase 2, Dose-Escalation, Safety and Efficacy Study of Tildacerfont (SPR001) for the Treatment of Patients with Classic Congenital Adrenal HyperplasiaSarafoglou, Kyriakie⋅Newfield, Ron⋅Vogiatzi, Maria⋅Imel, Erik⋅Odugbesan, A⋅Madu, Ivy-Joan⋅Nakhle, Samer⋅Howerton, Alexis⋅Huang, Michael⋅Vandever, Kelly⋅Lin, Rong⋅Wu-Zhang, Alyssa and Auchus, RichardJournal of the Endocrine Society, vol. 3, (no. Supplement_1), 2019-04-15.
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Sustained efficacy and safety of burosumab, a fully human anti-FGF23 monoclonal antibody, in children and early adolescents with X-linked hypophosphatemiaHogler, Wolfgang⋅Carpenter, Thomas⋅Imel, Erik⋅Portale, Anthony⋅Boot, Annemieke⋅Linglart, Agnes⋅Padidela, Raja⋅Hoff, William van't⋅Mao, Meng⋅Skrinar, Alison⋅Martin, Javier San and Whyte, MichaelBone Abstracts, 2019-07-31.
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The Lifelong Impact of X-Linked Hypophosphatemia: Results From a Burden of Disease SurveySkrinar, Alison⋅Dvorak-Ewell, Melita⋅Evins, Ayla⋅Macica, Carolyn⋅Linglart, Agnès⋅Imel, Erik A⋅Theodore-Oklota, Christina and San Martin, JavierJournal of the Endocrine Society, vol. 3, (no. 7), pp. 1334, 2019-Jul-01.
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2018
A PHASE 3 RANDOMIZED, PLACEBO-CONTROLLED STUDY INVESTIGATING BUROSUMAB FOR ADULT X-LINKED HYPOPHOSPHATEMIA (XLH)Beur, Suzanne⋅Carpenter, Thomas⋅Briot, Karine⋅Imel, Erik⋅Kamenický, Peter⋅Ruppe, Mary⋅Portale, Anthony⋅Weber, Thomas⋅Pitukcheewanont, Pisit⋅Cheong, Hae⋅Imanishi, Yasuo⋅Ito, Nobuaki⋅Lachmann, Robin⋅Tanaka, Hiroyuki⋅Zhang, Lin⋅Theodore-Oklota, Christina⋅Mealiffe, Matt⋅Martin, Javier and Insogna, KarlEndocrine Practice, vol. 24, pp. 112, 20180401.
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A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial Evaluating the Efficacy of Burosumab, an Anti-FGF23 Antibody, in Adults With X-Linked Hypophosphatemia: Week 24 Primary Analysis.Insogna, Karl L⋅Briot, Karine⋅Imel, Erik A⋅Kamenický, Peter⋅Ruppe, Mary D⋅Portale, Anthony A⋅Weber, Thomas⋅Pitukcheewanont, Pisit⋅Cheong, Hae Il⋅Jan de Beur, Suzanne⋅Imanishi, Yasuo⋅Ito, Nobuaki⋅Lachmann, Robin H⋅Tanaka, Hiroyuki⋅Perwad, Farzana⋅Zhang, Lin⋅Chen, Chao-Yin⋅Theodore-Oklota, Christina⋅Mealiffe, Matt⋅San Martin, Javier and Carpenter, Thomas OJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, June 26, 2018.
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BUROSUMAB FOR X-LINKED HYPOPHOSPHATEMIA (XLH): RESULTS FROM TWO PEDIATRIC PHASE 2 TRIALSPortale, Anthony⋅Imel, Erik⋅Whyte, Michael⋅Boot, Annemieke⋅Högler, Wolfgang⋅Linglart, Agnès⋅Padidela, Raja⋅Hoff, William⋅Gottesman, Gary⋅Mao, Meng⋅Skrinar, Alison⋅Martin, Javier and Carpenter, ThomasEndocrine Practice, vol. 24, pp. 120, 20180401.
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Burosumab Improved Rickets, Phosphate Metabolism, and Clinical Outcomes Compared to Conventional Therapy in Children with X-Linked Hypophosphatemia (XLH) - A Randomized Controlled Phase 3 StudyNilsson, Ola⋅Whyte, Michael P⋅Imel, Erik A⋅Munns, Craig⋅Portale, Anthony A⋅Ward, Leanne⋅Simmons, Jill H⋅Padidela, Raja⋅Namba, Noriyuki⋅Cheong, Hae Il⋅Mao, Meng⋅Skrinar, Alison⋅Chen, Chao-Yin⋅Martin, Javier San and Glorieux, FrancisHormone Research in Paediatrics, vol. 90, (no. Suppl.1), pp. 57, 2018.
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Burosumab Therapy in Children with X-Linked Hypophosphatemia.Carpenter, Thomas O⋅Whyte, Michael P⋅Imel, Erik A⋅Boot, Annemieke M⋅Högler, Wolfgang⋅Linglart, Agnès⋅Padidela, Raja⋅Van't Hoff, William⋅van't Hoff, William⋅Mao, Meng⋅Chen, Chao-Yin⋅Skrinar, Alison⋅Kakkis, Emil⋅San Martin, Javier and Portale, Anthony AThe New England journal of medicine, vol. 378, (no. 21), pp. 1987-1998, May 24, 2018.
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Genetic Variants Associated with Circulating Fibroblast Growth Factor 23C, Robinson-Cohen⋅Robinson-Cohen, Cassianne⋅Robinson-Cohen, Cassianne⋅Robinson-Cohen, Cassianne⋅Robinson-Cohen, Cassianne⋅Robinson Cohen, Cassianne⋅TM, Bartz⋅Bartz, Traci M⋅Bartz, Traci M⋅Bartz, Traci M⋅Bartz, Traci M.⋅Bartz, Traci M⋅Lai, Dongbing⋅D, Lai⋅Lai, Dongbing⋅Lai, Dongbing⋅Lai, Dongbing⋅Lai, Dongbing⋅Alp Ikizler, T.⋅Ikizler, T Alp⋅Ikizler, T Alp⋅Ikizler, T Alp⋅TA, Ikizler⋅Ikizler, T Alp⋅M, Peacock⋅Peacock, Munro⋅Peacock, Munro⋅Peacock, Munro⋅Peacock, Munro⋅Peacock, Munro⋅Imel, Erik A⋅EA, Imel⋅Imel, Erik A⋅Imel, Erik A⋅Imel, Erik A⋅Imel, Erik A.⋅Michos, Erin D⋅Michos, Erin D⋅Michos, Erin D.⋅Michos, Erin D⋅ED, Michos⋅Michos, Erin D⋅Foroud, Tatiana M⋅Foroud, Tatiana M⋅Foroud, Tatiana M⋅Foroud, Tatiana M.⋅Foroud, Tatiana M⋅TM, Foroud⋅Akesson, Kristina⋅K, Akesson⋅Akesson, Kristina⋅Akesson, Kristina⋅Akesson, Kristina⋅Akesson, Kristina⋅Taylor, Kent D⋅Taylor, Kent D⋅Taylor, Kent D⋅Taylor, Kent D⋅KD, Taylor⋅Taylor, Kent D.⋅Malmgren, Linnea⋅Malmgren, Linnea⋅L, Malmgren⋅Malmgren, Linnea⋅Malmgren, Linnea⋅Malmgren, Linnea⋅Matsushita, Kunihiro⋅K, Matsushita⋅Matsushita, Kunihiro⋅Matsushita, Kunihiro⋅Matsushita, Kunihiro⋅Matsushita, Kunihiro⋅Nethander, Maria⋅Nethander, Maria⋅Nethander, Maria⋅Nethander, Maria⋅Nethander, Maria⋅M, Nethander⋅Eriksson, Joel⋅Eriksson, Joel⋅Eriksson, Joel⋅Eriksson, Joel⋅Eriksson, Joel⋅BR, Kestenbaum⋅Ohlsson, Claes⋅Ohlsson, Claes⋅Ohlsson, Claes⋅Ohlsson, Claes⋅Ohlsson, Claes⋅Mellström, Daniel⋅Mellström, Daniel⋅Mellström, Daniel⋅Mellström, Daniel⋅Mellström, Daniel⋅Wolf, Myles⋅Wolf, Myles⋅Wolf, Myles⋅Wolf, Myles⋅Wolf, Myles⋅Ljunggren, Osten⋅Ljunggren, Osten⋅Ljunggren, Osten⋅Ljunggren, Osten⋅Ljunggren, Osten⋅McGuigan, Fiona⋅McGuigan, Fiona⋅McGuigan, Fiona⋅McGuigan, Fiona⋅McGuigan, Fiona⋅Rotter, Jerome I⋅Rotter, Jerome I.⋅Rotter, Jerome I⋅Rotter, Jerome I⋅Rotter, Jerome I⋅Karlsson, Magnus⋅Karlsson, Magnus⋅Karlsson, Magnus⋅Karlsson, Magnus⋅Karlsson, Magnus⋅Econs, Michael J⋅Econs, Michael J⋅Econs, Michael J⋅Econs, Michael J.⋅Econs, Michael J⋅Ix, Joachim H⋅Ix, Joachim H.⋅Ix, Joachim H⋅Ix, Joachim H⋅Ix, Joachim H⋅Lutsey, Pamela L⋅Lutsey, Pamela L⋅Lutsey, Pamela L.⋅Lutsey, Pamela L⋅Lutsey, Pamela L⋅Psaty, Bruce M⋅Psaty, Bruce M⋅Psaty, Bruce M⋅Psaty, Bruce M⋅Psaty, Bruce M.⋅De Boer, Ian H.⋅de Boer, Ian H⋅de Boer, Ian H⋅de Boer, Ian H⋅de Boer, Ian H⋅Kestenbaum, Bryan R⋅Kestenbaum, Bryan R.⋅Kestenbaum, Bryan R⋅Kestenbaum, Bryan R and Kestenbaum, Bryan RJournal of the American Society of Nephrology : JASN, vol. 29, (no. 10), pp. 2592, 2018-10-00.
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Osteogenesis Imperfecta Type I: Recognition in Primary CareTatlock, Rexanna L⋅Tatlock, Rexanna L.⋅Edwards, Nancy⋅Edwards, Nancy⋅Imel, Erik A.⋅Imel, Erik A⋅Foli, Karen J and Foli, Karen J.The Journal for Nurse Practitioners, vol. 14, (no. 6), pp. 476, June 2018.
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Prevalence of Nephrocalcinosis in Pseudohypoparathyroidism: Is Screening Necessary?Hansen, David W⋅Hansen, David W⋅Hansen, David W⋅Maahs, David M⋅Hansen, David W⋅Nebesio, Todd D⋅Nebesio, Todd D⋅Nebesio, Todd D⋅Nebesio, Todd D⋅Di Meglio, Linda A⋅DiMeglio, Linda A⋅DiMeglio, Linda A⋅DiMeglio, Linda A⋅Eugster, Erica A⋅Eugster, Erica A⋅Eugster, Erica A⋅Eugster, Erica A⋅Imel, Erik A⋅Imel, Erik A⋅Imel, Erik A and Imel, Erik AThe Journal of Pediatrics, vol. 199, pp. 266, August 2018.
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2017
A randomized, open-label Phase 2 study of KRN23, an investigational fully human Anti-FGF23 monoclonal antibody, in children with X-linked Hypophosphatemia (XLH)Hogler, Wolfgang⋅Portale, Anthony⋅Imel, Erik⋅Boot, Annemieke⋅Linglart, Agnes⋅Padidela, Raja⋅van't, Hoff William⋅Whyte, Michael⋅Mao, Meng⋅Skrinar, Alison⋅Martin, Javier San and Carpenter, ThomasBone Abstracts, 2017-07-11.
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Effects of KRN23, a fully human anti-FGF23 monoclonal antibody, on functional outcomes in children with X-linked hypophosphatemia (XLH): results from a randomized, open-label Phase 2 studyImel, Erik⋅Carpenter, Thomas⋅Linglart, Agnes⋅Boot, Annemieke⋅Hogler, Wolfgang⋅Padidela, Raja⋅van't, Hoff William⋅Portale, Anthony⋅Mao, Meng⋅Skrinar, Alison⋅San, Martin Javier and Whyte, Michael PBone Abstracts, 2017-07-11.
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Infants With Congenital Adrenal Hyperplasia Are at Risk for Hypercalcemia, Hypercalciuria, and NephrocalcinosisSchoelwer, Melissa J⋅Schoelwer, Melissa J⋅Schoelwer, Melissa J⋅Viswanathan, Vidhya⋅Viswanathan, Vidhya⋅Viswanathan, Vidhya⋅Wilson, Amy⋅Wilson, Amy⋅Wilson, Amy⋅Nailescu, Corina⋅Nailescu, Corina⋅Nailescu, Corina⋅Imel, Erik A⋅Imel, Erik A and Imel, Erik AJournal of the Endocrine Society, vol. 1, (no. 9), pp. 1167, 2017-Sep-01.
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KRN23 effects on phosphate and vitamin D dysregulation in children <5 years old with X-Linked Hypophosphatemia (XLH)Imel, Erik⋅Carpenter, Thomas⋅Gottesman, Gary S⋅Martin, Javier San⋅Mao, Meng⋅Skrinar, Alison and Whyte, Michael PBone Abstracts, 2017-07-11.
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Unexpected widespread hypophosphatemia and bone disease associated with elemental formula use in infants and childrenGonzalez Ballesteros, Luisa F⋅Gonzalez Ballesteros, Luisa F⋅Ma, Nina S⋅Ma, Nina S⋅Gordon, Rebecca J⋅Gordon, Rebecca J⋅Ward, Leanne⋅Ward, Leanne⋅Backeljauw, Philippe⋅Backeljauw, Philippe⋅Wasserman, Halley⋅Wasserman, Halley⋅Weber, David R⋅Weber, David R⋅Di Meglio, Linda A⋅DiMeglio, Linda A⋅Gagne, Julie⋅Gagne, Julie⋅Stein, Robert⋅Stein, Robert⋅Cody, Declan⋅Cody, Declan⋅Simmons, Kimber⋅Simmons, Kimber⋅Zimakas, Paul⋅Zimakas, Paul⋅Topor, Lisa Swartz⋅Topor, Lisa Swartz⋅Agrawal, Sungeeta⋅Agrawal, Sungeeta⋅Calabria, Andrew⋅Calabria, Andrew⋅Tebben, Peter⋅Tebben, Peter⋅Faircloth, Ruth⋅Faircloth, Ruth⋅Imel, Erik A⋅Imel, Erik A⋅Casey, Linda⋅Casey, Linda⋅Carpenter, Thomas O and Carpenter, Thomas OBone, vol. 97, pp. 292, April 2017.
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2016
Disparities in osteoporosis treatmentsLiu, Z⋅Weaver, J⋅de Papp, A⋅Li, Z⋅Martin, J⋅Allen, K⋅Hui, S and Imel, EOsteoporosis International, vol. 27, (no. 2), pp. 509-519, Feb 2016.
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Effect of four monthly doses of a human monoclonal anti-FGF23 antibody (KRN23) on quality of life in X-linked hypophosphatemia.Ruppe, Mary D⋅Zhang, Xiaoping⋅Imel, Erik A⋅Weber, Thomas J⋅Klausner, Mark A⋅Ito, Takahiro⋅Vergeire, Maria⋅Humphrey, Jeffrey S⋅Glorieux, Francis H⋅Portale, Anthony A⋅Insogna, Karl⋅Peacock, Munro and Carpenter, Thomas OBone reports, vol. 5, pp. 158-162, December 2016.
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Effect of KRN23, a fully human anti-FGF23 monoclonal antibody, on rickets in children with X-linked hypophosphatemia (XLH): 40-week interim results from a randomized, open-label phase 2 studyPadidela, Raja⋅van't, Hoff William⋅Hogler, Wolfgang⋅Portale, Anthony⋅Imel, Erik⋅Boot, Annemieke⋅Linglart, Agnes⋅Whyte, Michael⋅Skrinar, Alison⋅San, Martin Javier and Carpenter, ThomasEndocrine Abstracts, 2016-11-14.
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Genome-wide association study of serum iron phenotypes in premenopausal women of European descent.Koller, Daniel L⋅Koller, Daniel L⋅Imel, Erik A⋅Imel, Erik A⋅Lai, Dongbing⋅Lai, Dongbing⋅Padgett, Leah R⋅Padgett, Leah R⋅Acton, Dena⋅Acton, Dena⋅Gray, Amie⋅Gray, Amie⋅Peacock, Munro⋅Peacock, Munro⋅Econs, Michael J⋅Econs, Michael J⋅Foroud, Tatiana and Foroud, TatianaBlood cells, molecules & diseases, vol. 57, pp. 50-53, March 2016.
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Pharmacokinetics and pharmacodynamics of a human monoclonal anti-FGF23 antibody (KRN23) in the first multiple ascending-dose trial treating adults with X-linked hypophosphatemia.Zhang, Xiaoping⋅Imel, Erik A⋅Ruppe, Mary D⋅Weber, Thomas J⋅Klausner, Mark A⋅Ito, Takahiro⋅Vergeire, Maria⋅Humphrey, Jeffrey⋅Glorieux, Francis H⋅Portale, Anthony A⋅Insogna, Karl⋅Carpenter, Thomas O and Peacock, MunroJournal of clinical pharmacology, vol. 56, (no. 2), pp. 176-185, February 2016.
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Population pharmacokinetic and pharmacodynamic analyses from a 4-month intradose escalation and its subsequent 12-month dose titration studies for a human monoclonal anti-FGF23 antibody (KRN23) in adults with X-linked hypophosphatemia.Zhang, Xiaoping⋅Peyret, Thomas⋅Gosselin, Nathalie H⋅Marier, J F⋅Imel, Erik A and Carpenter, Thomas OJournal of clinical pharmacology, vol. 56, (no. 4), pp. 429-438, April 2016.
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Proportion of osteoporotic women remaining at risk for fracture despite adherence to oral bisphosphonates.Imel, Erik⋅Imel, Erik A⋅Imel, Erik⋅Eckert, George⋅Eckert, George⋅Eckert, George⋅Modi, Ankita⋅Modi, Ankita⋅Modi, Ankita⋅Li, Zhuokai⋅Li, Zhuokai⋅Li, Zhuokai⋅Martin, Joel⋅Martin, Joel⋅Martin, Joel⋅de Papp, Anne⋅Papp, Anne⋅Papp, Anne⋅Allen, Katie⋅Allen, Katie⋅Allen, Katie⋅Johnston, C.⋅Johnston, C Conrad⋅Johnston, C.⋅Hui, Siu L⋅Hui, Siu⋅Hui, Siu⋅Liu, Ziyue⋅Liu, Ziyue and Liu, ZiyueBone, vol. 83, pp. 267-275, February 2016.
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Serum fibroblast growth factor 23, serum iron and bone mineral density in premenopausal women.Imel, Erik A⋅Liu, Ziyue⋅McQueen, Amie K⋅Acton, Dena⋅Acton, Anthony⋅Padgett, Leah R⋅Peacock, Munro and Econs, Michael JBone, vol. 86, pp. 98-105, May 2016.
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2015
A Clinician's Guide to X‐Linked HypophosphatemiaCarpenter, Thomas O⋅Imel, Erik A⋅Holm, Ingrid A⋅Jan de Beur, Suzanne M and Insogna, Karl LJournal of Bone and Mineral Research, vol. 30, (no. 2), pp. 394, February 2015.
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