34 Publications (Page 1 of 2)
2018
Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversificationDonnelly, Christopher R⋅Shah, Amol A⋅Mistretta, Charlotte M⋅Bradley, Robert M and Pierchala, Brian AProceedings of the National Academy of Sciences of the United States of America, vol. 115, (no. 3), pp. E525, 2018-Jan-16.
| Journal Article
Non-canonical Ret signaling augments p75-mediated cell death in developing sympathetic neurons.Donnelly, Christopher R⋅Gabreski, Nicole A⋅Suh, Esther B⋅Chowdhury, Monzurul and Pierchala, Brian AThe Journal of cell biology, July 17, 2018.
| Journal Article
Semaphorin3A Signaling Is Dispensable for Motor Axon Reinnervation of the Adult Neuromuscular JunctionShadrach, Jennifer L and Pierchala, Brian AeNeuro, vol. 5, (no. 3), pp. ENEURO.0155-17.2018, 2018 May-Jun.
| Journal Article
2017
p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret SignalingChen, Zhijiang⋅Donnelly, Christopher R⋅Dominguez, Bertha⋅Harada, Yoshinobu⋅Lin, Weichun⋅Halim, Alan S⋅Bengoechea, Tasha G⋅Pierchala, Brian A and Lee, Kuo-FenCell Reports, vol. 21, (no. 3), pp. 720, 2017-10-17.
| Journal Article
2016
Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction.Gabreski, Nicole A⋅Vaghasia, Janki K⋅Novakova, Silvia S⋅McDonald, Neil Q and Pierchala, Brian AThe Journal of biological chemistry, vol. 291, (no. 31), pp. 16249-16262, July 29, 2016.
| Journal Article
Semaphorin 3A is a retrograde cell death signal in developing sympathetic neuronsWehner, Amanda B⋅Abdesselem, Houari⋅Dickendesher, Travis L⋅Imai, Fumiyasu⋅Yoshida, Yutaka⋅Giger, Roman J and Pierchala, Brian AJournal of Cell Science, vol. 129, (no. 10), pp. e1.2, 2016-05-15.
| Journal Article
Semaphorin 3A is a retrograde cell death signal in developing sympathetic neurons.Wehner, Amanda B⋅Abdesselem, Houari⋅Dickendesher, Travis L⋅Imai, Fumiyasu⋅Yoshida, Yutaka⋅Giger, Roman J and Pierchala, Brian ADevelopment (Cambridge, England), vol. 143, (no. 9), pp. 1560-1570, May 1, 2016.
| Journal Article
The p75 neurotrophin receptor augments survival signaling in the striatum of pre-symptomatic Q175(WT/HD) mice.Wehner, A B⋅Milen, A M⋅Albin, R L and Pierchala, B ANeuroscience, vol. 324, pp. 297-306, June 2, 2016.
| Journal Article
2015
Lipid Rafts Are Physiologic Membrane Microdomains Necessary for the Morphogenic and Developmental Functions of Glial Cell Line-Derived Neurotrophic Factor In Vivo.Tsui, Cynthia C⋅Gabreski, Nicole A⋅Hein, Sarah J and Pierchala, Brian AThe Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 35, (no. 38), pp. 13233-13243, September 23, 2015.
| Journal Article
2014
CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains.Calco, Gina N⋅Stephens, Olivia R⋅Donahue, Laura M⋅Tsui, Cynthia C and Pierchala, Brian AThe Journal of biological chemistry, vol. 289, (no. 11), pp. 7307-19, 2014/Mar/14.
| Journal Article
Polarized expression of p75(NTR) specifies axons during development and adult neurogenesis.Zuccaro, Emanuela⋅Bergami, Matteo⋅Vignoli, Beatrice⋅Bony, Guillaume⋅Pierchala, Brian A⋅Santi, Spartaco⋅Cancedda, Laura and Canossa, MarcoCell reports, vol. 7, (no. 1), pp. 138-152, April 10, 2014.
| Journal Article
2012
Expression of axonal protein degradation machinery in sympathetic neurons is regulated by nerve growth factor.Frampton, John P⋅Guo, Chong and Pierchala, Brian AJournal of neuroscience research, vol. 90, (no. 8), pp. 1533-46, 2012/Aug.
| Journal Article
Ret is a multifunctional coreceptor that integrates diffusible- and contact-axon guidance signals.Bonanomi, Dario⋅Chivatakarn, Onanong⋅Bai, Ge⋅Abdesselem, Houari⋅Lettieri, Karen⋅Marquardt, Till⋅Pierchala, Brian A and Pfaff, SamuelCell, vol. 148, (no. 3), pp. 568-82, 2012/Feb/3.
| Journal Article
2011
Generation of mice with a conditional allele for the p75 NTR neurotrophin receptor geneBogenmann, Emil⋅Thomas, Penny⋅Li, Qianfeng⋅Kim, Jieun⋅Yang, Liang‐tung⋅Pierchala, Brian and Kaartinen, Vesa2011-11.
| Journal Article
Generation of mice with a conditional allele for the p75(NTR) neurotrophin receptor gene.Bogenmann, Emil⋅Thomas, Penny S⋅Li, Qianfeng⋅Kim, Jieun⋅Yang, Liang-Tung⋅Pierchala, Brian A and Kaartinen, VesaGenesis (New York, N.Y. : 2000), vol. 49, (no. 11), pp. 862-9, 2011/Nov.
| Journal Article
2010
Proteomic analysis of the slit diaphragm complex: CLIC5 is a protein critical for podocyte morphology and function.Pierchala, Brian A⋅Muñoz, Maura R and Tsui, Cynthia CKidney international, vol. 78, (no. 9), pp. 868-82, 2010/Nov.
| Journal Article
The differential axonal degradation of Ret accounts for cell-type-specific function of glial cell line-derived neurotrophic factor as a retrograde survival factor.Tsui, Cynthia C and Pierchala, Brian AThe Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 30, (no. 15), pp. 5149-58, 2010/Apr/14.
| Journal Article
2008
CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.Tsui, Cynthia C and Pierchala, Brian AThe Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 28, (no. 35), pp. 8789-800, 2008/Aug/27.
| Journal Article
2006
Glial cell line-derived neurotrophic factor and its receptor ret is a novel ligand-receptor complex critical for survival response during podocyte injury.Tsui, Cynthia C⋅Shankland, Stuart J and Pierchala, Brian AJournal of the American Society of Nephrology : JASN, vol. 17, (no. 6), pp. 1543-52, 2006/Jun.
| Journal Article
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation.Pierchala, Brian A⋅Milbrandt, Jeffrey and Johnson, Eugene MThe Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 26, (no. 10), pp. 2777-2787, March 8, 2006.
| Journal Article
Glial Cell Line-Derived Neurotrophic Factor-Dependent Recruitment of Ret into Lipid Rafts Enhances Signaling by Partitioning Ret from Proteasome-Dependent DegradationPierchala, Brian A⋅Milbrandt, Jeffrey D and Johnson, Eugene MJournal of Neuroscience, vol. 26, (no. 10), pp. 2777-2787, 2006.
| Journal Article
2005
Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells.Lee, Chul-Sang⋅Lee, Chul-Sang⋅Tee, Lee Y⋅Tee, Lee Y.⋅Dusenbery, Susan⋅Dusenbery, Susan⋅Takata, Toshihiro⋅Takata, Toshihiro⋅Golden, Judy⋅Golden, Judith P.⋅Pierchala, Brian A.⋅Pierchala, Brian A⋅Gottlieb, David I.⋅Gottlieb, David I⋅Johnson, Eugene M.⋅Johnson, Eugene M⋅Choi, Dennis W.⋅Choi, Dennis W⋅Snider, B. J and Joy Snider, B.Experimental neurology, vol. 191, (no. 1), pp. 65-76, 2005/Jan.
| Journal Article
2004
Nerve Growth Factor Promotes the Survival of Sympathetic Neurons through the Cooperative Function of the Protein Kinase C and Phosphatidylinositol 3-Kinase PathwaysPierchala, Brian A⋅Ahrens, RC⋅Paden, AJ and Johnson, Eugene MJournal of Biological Chemistry, vol. 279, (no. 27), pp. 27986-27993, 2004.
| Journal Article
2002
Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.Harris, Charles A⋅Deshmukh, Mohanish P⋅Pierchala, Brian A⋅Maroney, Anna C and Johnson, Eugene MThe Journal of Neuroscience, vol. 22, (no. 1), pp. 103-13, 2002/Jan/1.
| Journal Article