34 Publications (Page 1 of 2)
2018
Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification
Donnelly, Christopher RShah, Amol AMistretta, Charlotte MBradley, Robert M and Pierchala, Brian A
Proceedings of the National Academy of Sciences of the United States of America, vol. 115, (no. 3), pp. E525, 2018-Jan-16. | Journal Article
 
Non-canonical Ret signaling augments p75-mediated cell death in developing sympathetic neurons.
Donnelly, Christopher RGabreski, Nicole ASuh, Esther BChowdhury, Monzurul and Pierchala, Brian A
The Journal of cell biology, July 17, 2018. | Journal Article
 
Semaphorin3A Signaling Is Dispensable for Motor Axon Reinnervation of the Adult Neuromuscular Junction
Shadrach, Jennifer L and Pierchala, Brian A
eNeuro, vol. 5, (no. 3), pp. ENEURO.0155-17.2018, 2018 May-Jun. | Journal Article
2017
p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling
Chen, ZhijiangDonnelly, Christopher RDominguez, BerthaHarada, YoshinobuLin, WeichunHalim, Alan SBengoechea, Tasha GPierchala, Brian A and Lee, Kuo-Fen
Cell Reports, vol. 21, (no. 3), pp. 720, 2017-10-17. | Journal Article
2016
Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction.
Gabreski, Nicole AVaghasia, Janki KNovakova, Silvia SMcDonald, Neil Q and Pierchala, Brian A
The Journal of biological chemistry, vol. 291, (no. 31), pp. 16249-16262, July 29, 2016. | Journal Article
 
Semaphorin 3A is a retrograde cell death signal in developing sympathetic neurons
Wehner, Amanda BAbdesselem, HouariDickendesher, Travis LImai, FumiyasuYoshida, YutakaGiger, Roman J and Pierchala, Brian A
Journal of Cell Science, vol. 129, (no. 10), pp. e1.2, 2016-05-15. | Journal Article
 
Semaphorin 3A is a retrograde cell death signal in developing sympathetic neurons.
Wehner, Amanda BAbdesselem, HouariDickendesher, Travis LImai, FumiyasuYoshida, YutakaGiger, Roman J and Pierchala, Brian A
Development (Cambridge, England), vol. 143, (no. 9), pp. 1560-1570, May 1, 2016. | Journal Article
 
The p75 neurotrophin receptor augments survival signaling in the striatum of pre-symptomatic Q175(WT/HD) mice.
Wehner, A BMilen, A MAlbin, R L and Pierchala, B A
Neuroscience, vol. 324, pp. 297-306, June 2, 2016. | Journal Article
2015
Lipid Rafts Are Physiologic Membrane Microdomains Necessary for the Morphogenic and Developmental Functions of Glial Cell Line-Derived Neurotrophic Factor In Vivo.
Tsui, Cynthia CGabreski, Nicole AHein, Sarah J and Pierchala, Brian A
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 35, (no. 38), pp. 13233-13243, September 23, 2015. | Journal Article
2014
CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains.
Calco, Gina NStephens, Olivia RDonahue, Laura MTsui, Cynthia C and Pierchala, Brian A
The Journal of biological chemistry, vol. 289, (no. 11), pp. 7307-19, 2014/Mar/14. | Journal Article
 
Polarized expression of p75(NTR) specifies axons during development and adult neurogenesis.
Zuccaro, EmanuelaBergami, MatteoVignoli, BeatriceBony, GuillaumePierchala, Brian ASanti, SpartacoCancedda, Laura and Canossa, Marco
Cell reports, vol. 7, (no. 1), pp. 138-152, April 10, 2014. | Journal Article
2012
Expression of axonal protein degradation machinery in sympathetic neurons is regulated by nerve growth factor.
Frampton, John PGuo, Chong and Pierchala, Brian A
Journal of neuroscience research, vol. 90, (no. 8), pp. 1533-46, 2012/Aug. | Journal Article
 
Ret is a multifunctional coreceptor that integrates diffusible- and contact-axon guidance signals.
Bonanomi, DarioChivatakarn, OnanongBai, GeAbdesselem, HouariLettieri, KarenMarquardt, TillPierchala, Brian A and Pfaff, Samuel
Cell, vol. 148, (no. 3), pp. 568-82, 2012/Feb/3. | Journal Article
2011
Generation of mice with a conditional allele for the p75 NTR neurotrophin receptor gene
Bogenmann, EmilThomas, PennyLi, QianfengKim, JieunYang, Liang‐tungPierchala, Brian and Kaartinen, Vesa
2011-11. | Journal Article
 
Generation of mice with a conditional allele for the p75(NTR) neurotrophin receptor gene.
Bogenmann, EmilThomas, Penny SLi, QianfengKim, JieunYang, Liang-TungPierchala, Brian A and Kaartinen, Vesa
Genesis (New York, N.Y. : 2000), vol. 49, (no. 11), pp. 862-9, 2011/Nov. | Journal Article
2010
Proteomic analysis of the slit diaphragm complex: CLIC5 is a protein critical for podocyte morphology and function.
Pierchala, Brian AMuñoz, Maura R and Tsui, Cynthia C
Kidney international, vol. 78, (no. 9), pp. 868-82, 2010/Nov. | Journal Article
 
The differential axonal degradation of Ret accounts for cell-type-specific function of glial cell line-derived neurotrophic factor as a retrograde survival factor.
Tsui, Cynthia C and Pierchala, Brian A
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 30, (no. 15), pp. 5149-58, 2010/Apr/14. | Journal Article
2008
CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.
Tsui, Cynthia C and Pierchala, Brian A
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 28, (no. 35), pp. 8789-800, 2008/Aug/27. | Journal Article
2007
NGF augments the autophosphorylation of Ret via inhibition of ubiquitin-dependent degradation
Pierchala, Brian ATsui, Cynthia CMilbrandt, Jeffrey D and Johnson, Eugene M
Journal of Neurochemistry, vol. 100, (no. 5), pp. 1169-1176, Mar 2007. | Journal Article
2006
Glial cell line-derived neurotrophic factor and its receptor ret is a novel ligand-receptor complex critical for survival response during podocyte injury.
Tsui, Cynthia CShankland, Stuart J and Pierchala, Brian A
Journal of the American Society of Nephrology : JASN, vol. 17, (no. 6), pp. 1543-52, 2006/Jun. | Journal Article
 
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation.
Pierchala, Brian AMilbrandt, Jeffrey and Johnson, Eugene M
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 26, (no. 10), pp. 2777-2787, March 8, 2006. | Journal Article
 
Glial Cell Line-Derived Neurotrophic Factor-Dependent Recruitment of Ret into Lipid Rafts Enhances Signaling by Partitioning Ret from Proteasome-Dependent Degradation
Pierchala, Brian AMilbrandt, Jeffrey D and Johnson, Eugene M
Journal of Neuroscience, vol. 26, (no. 10), pp. 2777-2787, 2006. | Journal Article
2005
Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells.
Lee, Chul-SangLee, Chul-SangTee, Lee YTee, Lee Y.Dusenbery, SusanDusenbery, SusanTakata, ToshihiroTakata, ToshihiroGolden, JudyGolden, Judith P.Pierchala, Brian A.Pierchala, Brian AGottlieb, David I.Gottlieb, David IJohnson, Eugene M.Johnson, Eugene MChoi, Dennis W.Choi, Dennis WSnider, B. J and Joy Snider, B.
Experimental neurology, vol. 191, (no. 1), pp. 65-76, 2005/Jan. | Journal Article
2004
Nerve Growth Factor Promotes the Survival of Sympathetic Neurons through the Cooperative Function of the Protein Kinase C and Phosphatidylinositol 3-Kinase Pathways
Pierchala, Brian AAhrens, RCPaden, AJ and Johnson, Eugene M
Journal of Biological Chemistry, vol. 279, (no. 27), pp. 27986-27993, 2004. | Journal Article
2002
Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.
Harris, Charles ADeshmukh, Mohanish PPierchala, Brian AMaroney, Anna C and Johnson, Eugene M
The Journal of Neuroscience, vol. 22, (no. 1), pp. 103-13, 2002/Jan/1. | Journal Article