198 Publications (Page 7 of 8)
2020
Nf1 mutant tumors undergo transcriptome and kinome re-modeling after inhibition of either mTOR or MEK
Pucciarelli, Daniela⋅Pucciarelli, Daniela⋅Angus, Steven P⋅Angus, Steven P.⋅Huang, Benjamin⋅Huang, Benjamin⋅Zhang, Chi⋅Zhang, Chi⋅Nakaoka, Hiroki J⋅Nakaoka, Hiroki J⋅Krishnamurthi, Ganesh⋅Krishnamurthi, Ganesh⋅Bandyopadhyay, Sourav⋅Bandyopadhyay, Sourav⋅Clapp, D Wade⋅Clapp, D. Wade⋅Shannon, Kevin⋅Shannon, Kevin⋅Johnson, Gary L.⋅Johnson, Gary L⋅Nakamura, Jean L and Nakamura, Jean L
Molecular Cancer Therapeutics, pp. molcanther.1017.2019. | Journal Article
 
Nf1-Mutant Tumors Undergo Transcriptome and Kinome Remodeling after Inhibition of either mTOR or MEK
Pucciarelli, Daniela⋅Pucciarelli, Daniela⋅Angus, Steven P⋅Angus, Steven P.⋅Huang, Benjamin⋅Huang, Benjamin⋅Zhang, Chi⋅Zhang, Chi⋅Nakaoka, Hiroki J.⋅Nakaoka, Hiroki J⋅Krishnamurthi, Ganesh⋅Krishnamurthi, Ganesh⋅Bandyopadhyay, Sourav⋅Bandyopadhyay, Sourav⋅Clapp, D Wade⋅Clapp, D. Wade⋅Shannon, Kevin⋅Shannon, Kevin⋅Johnson, Gary L.⋅Johnson, Gary L⋅Nakamura, Jean L and Nakamura, Jean L.
Molecular Cancer Therapeutics. | Journal Article
2019
A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas
Gehlhausen, Jeffrey R⋅Hawley, Eric⋅Wahle, Benjamin Mark⋅He, Yongzheng⋅Edwards, Donna⋅Rhodes, Steven D⋅Lajiness, Jacquelyn D⋅Staser, Karl⋅Chen, Shi⋅Yang, Xianlin⋅Yuan, Jin⋅Li, Xiaohong⋅Jiang, Li⋅Smith, Abbi⋅Bessler, Waylan⋅Sandusky, George⋅Stemmer-Rachamimov, Anat⋅Stuhlmiller, Timothy J⋅Angus, Steven P⋅Johnson, Gary L⋅Nalepa, Grzegorz⋅Yates, Charles W⋅Wade Clapp, D and Park, Su-Jung
Human Molecular Genetics, vol. 28, (no. 4), pp. 583, 20190215. | Journal Article
 
DRES-13. DUAL KINASE INHIBITION TO COMBAT EGFR-INHIBITOR RESISTANCE IN GLIOBLASTOMA
Smithberger, Erin⋅Shelton, Abigail⋅Butler, Madison⋅Flores, Alex⋅Bash, Ryan⋅Angus, Steven⋅East, Michael⋅Sciaky, Noah⋅Dhruv, Harshil⋅Johnson, Gary⋅Berens, Michael⋅Furnari, Frank and Ryan Miller, C
Neuro-Oncology, vol. 21, (no. Supplement_6), pp. vi74, 20191111. | Journal Article
 
GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple-Negative Breast Cancer
Bevill, Samantha M⋅Olivares-Quintero, Jose F⋅Sciaky, Noah⋅Golitz, Brian T⋅Singh, Darshan⋅Beltran, Adriana S⋅Rashid, Naim U⋅Stuhlmiller, Timothy J⋅Hale, Andrew⋅Moorman, Nathaniel J⋅Santos, Charlene M⋅Angus, Steven P⋅Zawistowski, Jon S and Johnson, Gary L
Molecular cancer research : MCR, vol. 17, (no. 7), pp. 1518, 2019-07-00. | Journal Article
 
Inhibition of Aurora A Kinase in Combination with Chemotherapy Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma
Park, Steven⋅Lin, Carolina⋅Ren, Natalie⋅Angus, Steven⋅Dittmer, Dirk⋅Foote, Michael⋅Parton, Trevor⋅Bhatt, Aadra⋅Fedoriw, Yuri⋅Roth, Daniel⋅Cann, Marissa⋅Johnson, Gary and Damania, Blossom
Targeted Oncology, vol. 14, (no. 5), pp. 575, 20191000. | Journal Article
2018
CSIG-42. HIGH THROUGHPUT KINOME AND TRANSCRIPTOME ANALYSES REVEAL NOVEL THERAPEUTIC TARGETS IN NF2-DEFICIENT MENINGIOMA
Beauchamp, Roberta⋅Erdin, Serkan⋅Angus, Steven⋅Stuhlmiller, Timothy⋅Oblinger, Janet⋅Jordan, Justin⋅Haggarty, Stephen J⋅R. Plotkin, Scott⋅Chang, Long-Sheng⋅L. Johnson, Gary⋅F. Gusella, James and Ramesh, Vijaya
Neuro-Oncology, vol. 20, (no. suppl_6), pp. vi52, 20181105. | Journal Article
 
DRES-07. DEFINING THE MECHANISMS OF ACQUIRED RESISTANCE TO TYROSINE KINASE INHIBITORS IN EGFR-DRIVEN GLIOBLASTOMAS USING INTEGRATED KINOME AND TRANSCRIPTOME PROFILING
Shelton, Abigail⋅Smithberger, Erin⋅Butler, Madison⋅Flores, Alex⋅Bash, Ryan⋅Angus, Steven⋅Sciaky, Noah⋅Dhruv, Harshil⋅Johnson, Gary⋅Berens, Michael⋅Furnari, Frank and Miller, Ryan
Neuro-Oncology, vol. 20, (no. suppl_6), pp. vi77, 20181105. | Journal Article
 
DRES-08. DYNAMIC KINOME PROFILING OF GENETICALLY-DEFINED, EGFRvIII-DRIVEN MURINE ASTROCYTE MODELS OF GLIOBLASTOMA REVEALS TARGETS FOR DUAL KINASE INHIBITOR THERAPY
Smithberger, Erin⋅Shelton, Abigail⋅Butler, Madison⋅Flores, Alex⋅Bash, Ryan⋅Angus, Steven⋅Sciaky, Noah⋅Dhruv, Harshil⋅Johnson, Gary⋅Berens, Michael⋅Furnari, Frank and Miller, Ryan
Neuro-Oncology, vol. 20, (no. suppl_6), pp. vi77, 20181105. | Journal Article
 
Engineering a Protein Binder Specific for p38? with Interface Expansion
Hussain, M.⋅Angus, S.P. and Kuhlman, B.
Biochemistry, vol. 57, pp. 4526-4535. | Journal Article
 
EPH receptor signaling as a novel therapeutic target in NF2-deficient meningioma
Angus, Steven P⋅Angus, Steven P⋅Oblinger, Janet L⋅Oblinger, Janet L⋅Stuhlmiller, Timothy J⋅Stuhlmiller, Timothy J⋅DeSouza, Patrick A⋅DeSouza, Patrick A⋅Beauchamp, Roberta L⋅Beauchamp, Roberta L⋅Witt, Luke⋅Witt, Luke⋅Chen, Xin⋅Chen, Xin⋅Jordan, Justin T⋅Jordan, Justin T⋅Gilbert, Thomas S K⋅Gilbert, Thomas S K⋅Stemmer-Rachamimov, Anat⋅Stemmer-Rachamimov, Anat⋅Gusella, James F⋅Gusella, James F⋅Plotkin, Scott R⋅Plotkin, Scott R⋅Haggarty, Stephen J⋅Haggarty, Stephen J⋅Chang, Long-Sheng⋅Chang, Long-Sheng⋅Johnson, Gary L⋅Johnson, Gary L⋅Ramesh, Vijaya and Ramesh, Vijaya
Neuro-oncology, vol. 20, (no. 9), pp. 1196, 2018-08-02. | Journal Article
 
Epigenetic Mechanisms Regulating Adaptive Responses to Targeted Kinase Inhibitors in Cancer
Angus, Steven P⋅Angus, Steven P⋅Zawistowski, Jon S⋅Zawistowski, Jon S⋅Johnson, Gary L and Johnson, Gary L
Annual Review of Pharmacology and Toxicology, vol. 58, (no. 1), pp. 229, 20180106. | Journal Article
 
New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging
Brighton, Hailey E⋅Brighton, Hailey E⋅Angus, Steven P⋅Angus, Steven P⋅Bo, Tao⋅Bo, Tao⋅Roques, Jose⋅Roques, Jose⋅Tagliatela, Alicia C⋅Tagliatela, Alicia C⋅Darr, David B⋅Darr, David B⋅Karagoz, Kubra⋅Karagoz, Kubra⋅Sciaky, Noah⋅Sciaky, Noah⋅Gatza, Michael L⋅Gatza, Michael L⋅Sharpless, Norman E⋅Sharpless, Norman E⋅Johnson, Gary L⋅Johnson, Gary L⋅Bear, James E and Bear, James E
Cancer research, vol. 78, (no. 2), pp. 557, 2018-01-15. | Journal Article
 
Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer
Collins, Kyla A L⋅Collins, K.A.L.⋅Stuhlmiller, Timothy J⋅Stuhlmiller, T.J.⋅Zawistowski, Jon S⋅Zawistowski, J.S.⋅East, Michael P⋅East, M.P.⋅Pham, T.T.⋅Pham, Trang T⋅Hall, C.R.⋅Hall, Claire R⋅Goulet, Daniel R⋅Goulet, D.R.⋅Bevill, Samantha M⋅Bevill, S.M.⋅Angus, Steven P⋅Angus, S.P.⋅Velarde, S.H.⋅Velarde, Sara H⋅Sciaky, N.⋅Sciaky, Noah⋅Oprea, T.I.⋅Oprea, Tudor I⋅Graves, Lee M⋅Graves, L.M.⋅Johnson, Gary L⋅Johnson, G.L.⋅Gomez, S.M. and Gomez, Shawn M
Oncotarget, vol. 9, (no. 21), pp. 15497, 2018-Mar-20. | Journal Article
 
Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2
Allaway, Robert⋅Allaway, R.⋅Allaway, R.⋅Angus, Steve P⋅Allaway, Robert⋅Angus, S.P.⋅Angus, S.P.⋅Angus, Steve P⋅Beauchamp, Roberta L⋅Beauchamp, R.L.⋅Beauchamp, R.L.⋅Blakeley, J.O.⋅Blakeley, Jaishri O⋅Blakeley, J.O.⋅Beauchamp, Roberta L⋅Bott, M.⋅Blakeley, Jaishri O⋅Bott, Marga⋅Bott, M.⋅Bott, Marga⋅Burns, S.S.⋅Burns, S.S.⋅Burns, Sarah S⋅Carlstedt, Annemarie⋅Carlstedt, A.⋅Carlstedt, A.⋅Burns, Sarah S⋅Carlstedt, Annemarie⋅Chang, L.-S.⋅Chang, Long-Sheng⋅Chang, L.-S.⋅Chen, Xin⋅Chen, X.⋅Chen, X.⋅Chang, Long-Sheng⋅Clapp, D Wade⋅Clapp, D.W.⋅Chen, Xin⋅Clapp, D.W.⋅DeSouza, P.A.⋅Desouza, Patrick A⋅Clapp, D Wade⋅DeSouza, P.A.⋅Desouza, Patrick A⋅Erdin, Serkan⋅Erdin, S.⋅Erdin, S.⋅Fernandez-Valle, C.⋅Erdin, Serkan⋅Fernandez-Valle, Cristina⋅Fernandez-Valle, C.⋅Guinney, Justin⋅Fernandez-Valle, Cristina⋅Guinney, J.⋅Guinney, J.⋅Gusella, J.F.⋅Gusella, James F⋅Guinney, Justin⋅Gusella, J.F.⋅Haggarty, S.J.⋅Haggarty, Stephen J⋅Gusella, James F⋅Haggarty, S.J.⋅Johnson, G.L.⋅Johnson, Gary L⋅Haggarty, Stephen J⋅Johnson, G.L.⋅La Rosa, Salvatore⋅Johnson, Gary L⋅La Rosa, S.⋅La Rosa, S.⋅La Rosa, Salvatore⋅Morrison, Helen⋅Morrison, H.⋅Morrison, H.⋅Petrilli, A.M.⋅Petrilli, Alejandra M⋅Petrilli, A.M.⋅Morrison, Helen⋅Plotkin, S.R.⋅Petrilli, Alejandra M⋅Plotkin, S.R.⋅Plotkin, Scott R⋅Pratap, A.⋅Plotkin, Scott R⋅Pratap, Abhishek⋅Pratap, A.⋅Pratap, Abhishek⋅Ramesh, V.⋅Ramesh, V.⋅Ramesh, Vijaya⋅Sciaky, Noah⋅Sciaky, N.⋅Sciaky, N.⋅Ramesh, Vijaya⋅Sciaky, Noah⋅Stemmer-Rachamimov, Anat⋅Stemmer-Rachamimov, A.⋅Stemmer-Rachamimov, A.⋅Stemmer-Rachamimov, Anat⋅Stuhlmiller, Tim J⋅Stuhlmiller, T.J.⋅Stuhlmiller, T.J.⋅Stuhlmiller, Tim J⋅Talkowski, M.E.⋅Talkowski, M.E.⋅Talkowski, Michael E⋅Welling, D.B.⋅Welling, D.B.⋅Welling, D Bradley⋅Talkowski, Michael E⋅Yates, Charles W⋅Yates, C.W.⋅Welling, D Bradley⋅Yates, C.W.⋅Zawistowski, J.S.⋅Zawistowski, Jon S⋅Yates, Charles W⋅Zawistowski, J.S.⋅Zhao, Wen-Ning⋅Zhao, W.-N.⋅Zawistowski, Jon S⋅Zhao, W.-N. and Zhao, Wen-Ning
PLoS ONE, vol. 13. | Journal Article
2017
A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma
Krepler, Clemens⋅Krepler, C.⋅Krepler, Clemens⋅Krepler, Clemens⋅Sproesser, Katrin⋅Sproesser, K.⋅Sproesser, Katrin⋅Sproesser, Katrin⋅Brafford, P.⋅Brafford, Patricia⋅Brafford, Patricia⋅Brafford, Patricia⋅Beqiri, Marilda⋅Beqiri, Marilda⋅Beqiri, M.⋅Beqiri, Marilda⋅Garman, B.⋅Garman, Bradley⋅Garman, Bradley⋅Garman, Bradley⋅Xiao, Min⋅Xiao, M.⋅Xiao, Min⋅Xiao, Min⋅Shannan, Batool⋅Shannan, Batool⋅Shannan, B.⋅Shannan, Batool⋅Watters, Andrea⋅Watters, Andrea⋅Watters, A.⋅Watters, Andrea⋅Perego, Michela⋅Perego, Michela⋅Perego, Michela⋅Perego, M.⋅Zhang, G.⋅Zhang, Gao⋅Zhang, Gao⋅Zhang, Gao⋅Vultur, Adina⋅Vultur, A.⋅Vultur, Adina⋅Vultur, Adina⋅Yin, Xiangfan⋅Yin, X.⋅Yin, Xiangfan⋅Yin, Xiangfan⋅Liu, Qin⋅Liu, Qin⋅Liu, Qin⋅Liu, Q.⋅Anastopoulos, Ioannis N⋅Anastopoulos, I.N.⋅Anastopoulos, Ioannis N⋅Anastopoulos, Ioannis N⋅Wubbenhorst, Bradley⋅Wubbenhorst, Bradley⋅Wubbenhorst, B.⋅Wubbenhorst, Bradley⋅Wilson, Melissa A⋅Wilson, M.A.⋅Wilson, Melissa A⋅Wilson, Melissa A⋅Xu, Xiaowei⋅Xu, Wei⋅Xu, Wei⋅Xu, Xiaowei⋅Xu, W.⋅Xu, Wei⋅Xu, Xiaowei⋅Karakousis, Giorgos⋅Karakousis, Giorgos⋅Karakousis, G.⋅Karakousis, Giorgos⋅Feldman, Michael⋅Feldman, Michael⋅Feldman, Michael⋅Feldman, M.⋅Xu, X.⋅Amaravadi, R.⋅Amaravadi, Ravi⋅Amaravadi, Ravi⋅Amaravadi, Ravi⋅Gangadhar, T.C.⋅Gangadhar, Tara C⋅Gangadhar, Tara C⋅Gangadhar, Tara C⋅Elder, David E⋅Elder, David E⋅Elder, David E⋅Elder, D.E.⋅Haydu, Lauren E⋅Haydu, Lauren E⋅Haydu, Lauren E⋅Haydu, L.E.⋅Wargo, J.A.⋅Wargo, Jennifer A⋅Wargo, Jennifer A⋅Wargo, Jennifer A⋅Davies, M.A.⋅Davies, Michael A⋅Davies, Michael A⋅Davies, Michael A⋅Lu, Yiling⋅Lu, Yiling⋅Lu, Y.⋅Lu, Yiling⋅Mills, G.B.⋅Mills, Gordon B⋅Mills, Gordon B⋅Mills, Gordon B⋅Frederick, Dennie T⋅Frederick, Dennie T⋅Frederick, D.T.⋅Frederick, Dennie T⋅Barzily-Rokni, M.⋅Barzily-Rokni, Michal⋅Barzily-Rokni, Michal⋅Barzily-Rokni, Michal⋅Flaherty, Keith T⋅Flaherty, K.T.⋅Flaherty, Keith T⋅Flaherty, Keith T⋅Hoon, Dave S⋅Hoon, D.S.⋅Hoon, Dave S⋅Hoon, Dave S⋅Guarino, Michael⋅Guarino, M.⋅Guarino, Michael⋅Guarino, Michael⋅Bennett, J.J.⋅Bennett, Joseph J⋅Bennett, Joseph J⋅Bennett, Joseph J⋅Ryan, Randall W⋅Ryan, Randall W⋅Ryan, R.W.⋅Ryan, Randall W⋅Petrelli, Nicholas J⋅Petrelli, Nicholas J⋅Petrelli, Nicholas J⋅Petrelli, N.J.⋅Shields, Carol L⋅Shields, C.L.⋅Shields, Carol L⋅Shields, Carol L⋅Terai, Mizue⋅Terai, Mizue⋅Terai, Mizue⋅Terai, M.⋅Sato, T.⋅Sato, Takami⋅Sato, Takami⋅Sato, Takami⋅Aplin, Andrew E⋅Aplin, Andrew E⋅Aplin, Andrew E⋅Aplin, A.E.⋅Roesch, Alexander⋅Roesch, Alexander⋅Roesch, A.⋅Roesch, Alexander⋅Darr, David⋅Darr, David⋅Darr, David⋅Darr, D.⋅Angus, Steve⋅Angus, S.⋅Angus, Steve⋅Angus, Steve⋅Kumar, Rakesh⋅Kumar, R.⋅Kumar, Rakesh⋅Kumar, Rakesh⋅Halilovic, E.⋅Halilovic, Ensar⋅Halilovic, Ensar⋅Halilovic, Ensar⋅Caponigro, Giordano⋅Caponigro, Giordano⋅Caponigro, Giordano⋅Caponigro, G.⋅Jeay, Sebastien⋅Jeay, Sebastien⋅Jeay, S.⋅Jeay, Sebastien⋅Wuerthner, Jens⋅Wuerthner, Jens⋅Wuerthner, Jens⋅Wuerthner, J.⋅Walter, Annette⋅Walter, Annette⋅Walter, Annette⋅Walter, A.⋅Ocker, Matthias⋅Ocker, Matthias⋅Ocker, Matthias⋅Ocker, M.⋅Boxer, Matthew B⋅Boxer, Matthew B⋅Boxer, Matthew B⋅Boxer, M.B.⋅Schuchter, Lynn⋅Schuchter, L.⋅Schuchter, Lynn⋅Schuchter, Lynn⋅Nathanson, K.L.⋅Nathanson, Katherine L⋅Nathanson, Katherine L⋅Nathanson, Katherine L⋅Herlyn, Meenhard⋅Herlyn, Meenhard⋅Herlyn, Meenhard and Herlyn, M.
Cell Reports, vol. 21, pp. 1953-1967. | Journal Article
 
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma
McNeill, Robert S⋅McNeill, Robert S⋅McNeill, R. S.⋅Canoutas, D. A.⋅Canoutas, Demitra A⋅Canoutas, Demitra A⋅Stuhlmiller, Timothy J⋅Stuhlmiller, T. J.⋅Stuhlmiller, Timothy J⋅Dhruv, Harshil D⋅Dhruv, Harshil D⋅Dhruv, H. D.⋅Irvin, D. M.⋅Irvin, David M⋅Irvin, David M⋅Bash, Ryan E⋅Bash, Ryan E⋅Bash, R. E.⋅Angus, Steven P⋅Angus, S. P.⋅Angus, Steven P⋅Herring, Laura E⋅Herring, L. E.⋅Herring, Laura E⋅Simon, J. M.⋅Simon, Jeremy M⋅Simon, Jeremy M⋅Skinner, Kasey R⋅Skinner, Kasey R⋅Skinner, K. R.⋅Limas, J. C.⋅Limas, Juanita C⋅Limas, Juanita C⋅Chen, Xin⋅Chen, Xin⋅Chen, X.⋅Schmid, Ralf S⋅Schmid, Ralf S⋅Schmid, R. S.⋅Siegel, Marni B⋅Siegel, Marni B⋅Siegel, M. B.⋅Van Swearingen, Amanda E D⋅Van Swearingen, Amanda E D⋅Van Swearingen, A. E. D.⋅Hadler, Michael J⋅Hadler, M. J.⋅Hadler, Michael J⋅Sulman, Erik P⋅Sulman, E. P.⋅Sulman, Erik P⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, J. N.⋅Anders, C. K.⋅Anders, Carey K⋅Anders, Carey K⋅Graves, Lee M⋅Graves, Lee M⋅Graves, L. M.⋅Berens, Michael E⋅Berens, Michael E⋅Berens, M. E.⋅Johnson, Gary L⋅Johnson, G. L.⋅Johnson, Gary L⋅Miller, C Ryan⋅Miller, C. R. and Miller, C Ryan
Neuro-oncology, vol. 19, (no. 11), pp. 1480, 2017-Oct-19. | Journal Article
 
Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex
Zawistowski, Jon S⋅Bevill, Samantha M⋅Goulet, Daniel R⋅Stuhlmiller, Timothy J⋅Beltran, Adriana S⋅Olivares-Quintero, Jose F⋅Singh, Darshan⋅Sciaky, Noah⋅Parker, Joel S⋅Rashid, Naim U⋅Chen, Xin⋅Duncan, James S⋅Whittle, Martin C⋅Angus, Steven P⋅Velarde, Sara Hanna⋅Golitz, Brian T⋅He, Xiaping⋅Santos, Charlene⋅Darr, David B⋅Gallagher, Kristalyn⋅Graves, Lee M⋅Perou, Charles M⋅Carey, Lisa A⋅Earp, H Shelton and Johnson, Gary L
Cancer discovery, vol. 7, (no. 3), pp. 321, 2017-03-00. | Journal Article
 
Kinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Transducer and Activator of Transcription and Epidermal Growth Factor Receptor Inhibition
Stuhlmiller, T.J.⋅Stuhlmiller, T.J.⋅Stuhlmiller, Timothy J⋅Zawistowski, J.S.⋅Zawistowski, Jon S⋅Zawistowski, J.S.⋅Chen, Xin⋅Chen, X.⋅Chen, X.⋅Sciaky, N.⋅Sciaky, Noah⋅Sciaky, N.⋅Angus, S.P.⋅Angus, S.P.⋅Angus, Steven P⋅Hicks, S.T.⋅Hicks, S.T.⋅Hicks, Sean T⋅Parry, T.L.⋅Parry, Traci L⋅Parry, T.L.⋅Huang, W.⋅Huang, Wei⋅Huang, W.⋅Beak, Ju Youn⋅Beak, J.Y.⋅Beak, J.Y.⋅Willis, M.S.⋅Willis, Monte S⋅Willis, M.S.⋅Johnson, G.L.⋅Johnson, G.L.⋅Johnson, Gary L⋅Jensen, Brian C⋅Jensen, B.C. and Jensen, B.C.
Journal of the American Heart Association, vol. 6, (no. 10), pp. n/a, October 2017. | Journal Article
 
TBCRC 036: Window of opportunity clinical trial reveals adaptive kinome reprogramming in single and combination HER2-targeting in breast cancer (BrCa)
Angus, Steven P⋅Angus, Steven P⋅Stuhlmiller, Timothy⋅Stuhlmiller, Timothy⋅Sciaky, Noah⋅Sciaky, Noah⋅Chen, Xin⋅Chen, Xin⋅Naim, Rashid⋅Naim, Rashid⋅Tanioka, Maki⋅Tanioka, Maki⋅Gallagher, Kristalyn K⋅Gallagher, Kristalyn K⋅Forero, Andres⋅Forero, Andres⋅Krop, Ian E⋅Krop, Ian E⋅Thompson, Alastair Mark⋅Thompson, Alastair Mark⋅Murthy, Rashmi Krishna⋅Murthy, Rashmi Krishna⋅He, Xiaping⋅He, Xiaping⋅Perou, Charles M⋅Perou, Charles M⋅Earp, Shelton⋅Earp, Shelton⋅Carey, Lisa A⋅Carey, Lisa A⋅Johnson, Gary L and Johnson, Gary L
Journal of Clinical Oncology, vol. 35, (no. 15_suppl), pp. 1027, 2017-05-20. | Journal Article
2016
Abstract 4382: Intravital imaging of endogenous BRAFV600E melanoma reveals plasticity of tumor response and resistance to trametinib over time
Brighton, Hailey E⋅Angus, Steven⋅Bo, Tao⋅Darr, David⋅Sharpless, Norman E⋅Johnson, Gary L and Bear, James E
Cancer Research, vol. 76, (no. 14 Supplement), pp. 4382, 2016-07-15. | Journal Article
 
Abstract B24: Triple-negative breast cancer adaptive response to MEK inhibition is regulated by the induction of super-enhancers
Zawistowski, Jon S⋅Miller, Samantha M⋅Goulet, Daniel R⋅Stuhlmiller, Timothy J⋅Singh, Darshan⋅Sciaky, Noah⋅Velarde, Sara H⋅Angus, Steven P and Johnson, Gary L
Molecular Cancer Research, vol. 14, (no. 2 Supplement), pp. B24, 2016-02-00. | Journal Article
 
Abstract B25: BET bromodomain inhibition targets adaptive responses to lapatinib in HER2-positive breast cancer
Stuhlmiller, Timothy J⋅Miller, Samantha M⋅Zawistowski, Jon S⋅Duncan, James S⋅Angus, Steven P⋅Granger, Deborah A⋅Reuther, Rachel A⋅Collins, Kyla A.L⋅Shawn, Gomez M⋅Kuan, Pei-Fen⋅Chen, Xin⋅Sciaky, Noah and Johnson, Gary L
Molecular Cancer Research, vol. 14, (no. 2 Supplement), pp. B25, 2016-02-00. | Journal Article
2015
Alisertib, an Aurora a Kinase Inhibitor, Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma Cells
Park, Steven I⋅Lin, Carolina P⋅Dittmer, Dirk P⋅Angus, Steven P⋅Wang, Greg G⋅Fedoriw, Yuri D⋅Darr, David B⋅Roth, Daniel P⋅Sharpless, Norman E and Damania, Blossom
Blood, vol. 126, (no. 23), pp. 1551, 2015-12-03. | Journal Article
 
Inhibition of Lapatinib-induced Kinome Reprogramming in ERBB2-positive Breast Cancer by Targeting BET Family Bromodomains
Stuhlmiller, Timothy J⋅Stuhlmiller, Timothy J⋅Miller, Samantha M⋅Miller, Samantha M⋅Zawistowski, Jon S⋅Zawistowski, Jon S⋅Nakamura, Kazuhiro⋅Nakamura, Kazuhiro⋅Beltran, Adriana S⋅Beltran, Adriana S⋅Duncan, James S⋅Duncan, James S⋅Angus, Steven P⋅Angus, Steven P⋅Collins, Kyla A.L⋅Collins, Kyla A L⋅Granger, Deborah A⋅Granger, Deborah A⋅Reuther, Rachel A⋅Reuther, Rachel A⋅Graves, Lee M⋅Graves, Lee M⋅Gomez, Shawn M⋅Gomez, Shawn M⋅Kuan, Pei-Fen⋅Kuan, Pei-Fen⋅Parker, Joel S⋅Parker, Joel S⋅Chen, Xin⋅Chen, Xin⋅Sciaky, Noah⋅Sciaky, Noah⋅Carey, Lisa A⋅Carey, Lisa A⋅Earp, H Shelton⋅Earp, H. Shelton⋅Jin, Jian⋅Jin, Jian⋅Johnson, Gary L and Johnson, Gary L
Cell Reports, vol. 11, (no. 3), pp. 404, 2015-Apr-21. | Journal Article